Defining the epidemiology of bloodstream infections: the 'gold standard' of population-based assessment

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Publicat a:Epidemiology and Infection vol. 141, no. 10 (Oct 2013), p. 2149-2157
Autor principal: LAUPLAND, K B
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Cambridge University Press
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Accés en línia:Citation/Abstract
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100 1 |a LAUPLAND, K B 
245 1 |a Defining the epidemiology of bloodstream infections: the 'gold standard' of population-based assessment 
260 |b Cambridge University Press  |c Oct 2013 
513 |a Feature Journal Article 
520 3 |a SUMMARY Bloodstream infections (BSIs) are a major cause of morbidity and mortality. Although population-based studies have been proposed as an optimal means to define their epidemiology, the merit of these designs has not been well documented. This report investigated the potential value of using population-based designs in defining the epidemiology of BSIs. Population-based BSI surveillance was conducted in Calgary, Canada (population 1·24 million) and illustrative comparisons were made between the overall and selected subgroup cohorts within five main themes. The value of population denominator data, and age and gender standardization for calculation and comparison of incidence rates were demonstrated. In addition, a number of biases including those related to differential admission rates, selected hospital admission, and referral bias were highlighted in non-population-based cohorts. Due to their comprehensive nature and intrinsic minimization of bias, population-based designs should be considered the gold standard means of defining the epidemiology of an infectious disease. [PUBLICATION ABSTRACT]   Bloodstream infections (BSIs) are a major cause of morbidity and mortality. Although population-based studies have been proposed as an optimal means to define their epidemiology, the merit of these designs has not been well documented. This report investigated the potential value of using population-based designs in defining the epidemiology of BSIs. Population-based BSI surveillance was conducted in Calgary, Canada (population 1.24 million) and illustrative comparisons were made between the overall and selected subgroup cohorts within five main themes. The value of population denominator data, and age and gender standardization for calculation and comparison of incidence rates were demonstrated. In addition, a number of biases including those related to differential admission rates, selected hospital admission, and referral bias were highlighted in non-population-based cohorts. Due to their comprehensive nature and intrinsic minimization of bias, population-based designs should be considered the gold standard means of defining the epidemiology of an infectious disease. 
610 4 |a Alberta Health Services 
650 2 2 |a Adolescent 
650 2 2 |a Adult 
650 2 2 |a Aged 
650 2 2 |a Aged, 80 & over 
650 1 2 |a Bacteremia  |x epidemiology 
650 2 2 |a Canada  |x epidemiology 
650 2 2 |a Child 
650 2 2 |a Child, Preschool 
650 2 2 |a Cohort Studies 
650 2 2 |a Epidemiologic Methods 
650 1 2 |a Epidemiologic Research Design 
650 2 2 |a Female 
650 2 2 |a Humans 
650 2 2 |a Male 
650 2 2 |a Middle Aged 
650 2 2 |a Population Surveillance 
651 4 |a South Africa 
651 4 |a Canada 
651 4 |a Calgary Alberta Canada 
653 |a Infections 
653 |a Young adults 
653 |a Population-based studies 
653 |a Age 
653 |a Epidemiology 
653 |a Disease 
653 |a Gender 
653 |a Bacterial infections 
653 |a Regions 
653 |a Hospitals 
653 |a Standardization 
653 |a Personal health 
653 |a Males 
653 |a Health services 
653 |a Infectious diseases 
653 |a Population studies 
653 |a Social 
773 0 |t Epidemiology and Infection  |g vol. 141, no. 10 (Oct 2013), p. 2149-2157 
786 0 |d ProQuest  |t Health & Medical Collection 
856 4 1 |3 Citation/Abstract  |u https://www.proquest.com/docview/1428503915/abstract/embedded/6A8EOT78XXH2IG52?source=fedsrch 
856 4 0 |3 Full Text  |u https://www.proquest.com/docview/1428503915/fulltext/embedded/6A8EOT78XXH2IG52?source=fedsrch 
856 4 0 |3 Full Text - PDF  |u https://www.proquest.com/docview/1428503915/fulltextPDF/embedded/6A8EOT78XXH2IG52?source=fedsrch