Effect of wavelength and beam width on penetration in light-tissue interaction using computational methods
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| Publicado en: | Lasers in Medical Science vol. 32, no. 8 (Nov 2017), p. 1909 |
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| Autor principal: | |
| Otros Autores: | , , |
| Publicado: |
Springer Nature B.V.
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| Acceso en línea: | Citation/Abstract Full Text - PDF |
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| 022 | |a 0268-8921 | ||
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| 024 | 7 | |a 10.1007/s10103-017-2317-4 |2 doi | |
| 035 | |a 1953877257 | ||
| 045 | 2 | |b d20171101 |b d20171130 | |
| 084 | |a 65762 |2 nlm | ||
| 100 | 1 | |a Ash, Caerwyn |u School of Applied Computing, University of Wales Trinity Saint David, Swansea, UK | |
| 245 | 1 | |a Effect of wavelength and beam width on penetration in light-tissue interaction using computational methods | |
| 260 | |b Springer Nature B.V. |c Nov 2017 | ||
| 513 | |a Journal Article | ||
| 520 | 3 | |a Penetration depth of ultraviolet, visible light and infrared radiation in biological tissue has not previously been adequately measured. Risk assessment of typical intense pulsed light and laser intensities, spectral characteristics and the subsequent chemical, physiological and psychological effects of such outputs on vital organs as consequence of inappropriate output use are examined. This technical note focuses on wavelength, illumination geometry and skin tone and their effect on the energy density (fluence) distribution within tissue. Monte Carlo modelling is one of the most widely used stochastic methods for the modelling of light transport in turbid biological media such as human skin. Using custom Monte Carlo simulation software of a multi-layered skin model, fluence distributions are produced for various non-ionising radiation combinations. Fluence distributions were analysed using Matlab mathematical software. Penetration depth increases with increasing wavelength with a maximum penetration depth of 5378 μm calculated. The calculations show that a 10-mm beam width produces a fluence level at target depths of 1–3 mm equal to 73–88% (depending on depth) of the fluence level at the same depths produced by an infinitely wide beam of equal incident fluence. Meaning little additional penetration is achieved with larger spot sizes. Fluence distribution within tissue and thus the treatment efficacy depends upon the illumination geometry and wavelength. To optimise therapeutic techniques, light-tissue interactions must be thoroughly understood and can be greatly supported by the use of mathematical modelling techniques. | |
| 653 | |a Skin | ||
| 653 | |a Infrared radiation | ||
| 653 | |a Flux density | ||
| 653 | |a Mathematical analysis | ||
| 653 | |a Multilayers | ||
| 653 | |a Luminous intensity | ||
| 653 | |a Illumination | ||
| 653 | |a Computer applications | ||
| 653 | |a Physiological effects | ||
| 653 | |a Risk assessment | ||
| 653 | |a Organs | ||
| 653 | |a Computer simulation | ||
| 653 | |a Fluence | ||
| 653 | |a Monte Carlo simulation | ||
| 653 | |a Computer programs | ||
| 653 | |a Wavelength | ||
| 653 | |a Penetration depth | ||
| 653 | |a Ionizing radiation | ||
| 653 | |a Mathematical models | ||
| 653 | |a Psychological effects | ||
| 653 | |a Light | ||
| 653 | |a I.R. radiation | ||
| 653 | |a Combinations (mathematics) | ||
| 653 | |a Simulation | ||
| 653 | |a Luminance distribution | ||
| 653 | |a Energy distribution | ||
| 653 | |a Ultraviolet radiation | ||
| 700 | 1 | |a Dubec, Michael |u The Christie NHS Foundation Trust, Manchester, UK | |
| 700 | 1 | |a Donne, Kelvin |u School of Applied Computing, University of Wales Trinity Saint David, Swansea, UK | |
| 700 | 1 | |a Bashford, Tim |u School of Applied Computing, University of Wales Trinity Saint David, Swansea, UK | |
| 773 | 0 | |t Lasers in Medical Science |g vol. 32, no. 8 (Nov 2017), p. 1909 | |
| 786 | 0 | |d ProQuest |t Health & Medical Collection | |
| 856 | 4 | 1 | |3 Citation/Abstract |u https://www.proquest.com/docview/1953877257/abstract/embedded/6A8EOT78XXH2IG52?source=fedsrch |
| 856 | 4 | 0 | |3 Full Text - PDF |u https://www.proquest.com/docview/1953877257/fulltextPDF/embedded/6A8EOT78XXH2IG52?source=fedsrch |