Maternal influenza immunization in Malawi: Piloting a maternal influenza immunization program costing tool by examining a prospective program

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Publicado en:PLoS One vol. 12, no. 12 (Dec 2017), p. e0190006
Autor principal: Pecenka, Clint
Otros Autores: Munthali, Spy, Chunga, Paul, Levin, Ann, Morgan, Win, Lambach, Philipp, Bhat, Niranjan, Neuzil, Kathleen M, Ortiz, Justin R, Hutubessy, Raymond
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024 7 |a 10.1371/journal.pone.0190006  |2 doi 
035 |a 1981045741 
045 2 |b d20171201  |b d20171231 
084 |a 174835  |2 nlm 
100 1 |a Pecenka, Clint 
245 1 |a Maternal influenza immunization in Malawi: Piloting a maternal influenza immunization program costing tool by examining a prospective program 
260 |b Public Library of Science  |c Dec 2017 
513 |a Journal Article 
520 3 |a Background This costing study in Malawi is a first evaluation of a Maternal Influenza Immunization Program Costing Tool (Costing Tool) for maternal immunization. The tool was designed to help low- and middle-income countries plan for maternal influenza immunization programs that differ from infant vaccination programs because of differences in the target population and potential differences in delivery strategy or venue. Methods This analysis examines the incremental costs of a prospective seasonal maternal influenza immunization program that is added to a successful routine childhood immunization and antenatal care program. The Costing Tool estimates financial and economic costs for different vaccine delivery scenarios for each of the major components of the expanded immunization program. Results In our base scenario, which specifies a donated single dose pre-filled vaccine formulation, the total financial cost of a program that would reach 2.3 million women is approximately $1.2 million over five years. The economic cost of the program, including the donated vaccine, is $10.4 million over the same period. The financial and economic costs per immunized pregnancy are $0.52 and $4.58, respectively. Other scenarios examine lower vaccine uptake, reaching 1.2 million women, and a vaccine purchased at $2.80 per dose with an alternative presentation. Conclusion This study estimates the financial and economic costs associated with a prospective maternal influenza immunization program in a low-income country. In some scenarios, the incremental delivery cost of a maternal influenza immunization program may be as low as some estimates of childhood vaccination programs, assuming the routine childhood immunization and antenatal care systems are capable of serving as the platform for an additional vaccination program. However, purchasing influenza vaccines at the prices assumed in this analysis, instead of having them donated, is likely to be challenging for lower-income countries. This result should be considered as a starting point to understanding the costs of maternal immunization programs in low- and middle-income countries. 
653 |a Social 
653 |a Vaccines 
653 |a Womens health 
653 |a Pregnancy 
653 |a Influenza 
653 |a Dosage 
653 |a Immunization 
653 |a Economic impact 
653 |a Economics 
653 |a Cost analysis 
653 |a Children 
653 |a Income 
653 |a Decision making 
653 |a Tools 
653 |a Estimates 
653 |a Drug delivery systems 
653 |a Cervical cancer 
653 |a Refrigerators 
653 |a Useful life 
653 |a Capital costs 
653 |a Feasibility studies 
653 |a Software 
653 |a Low income areas 
700 1 |a Munthali, Spy 
700 1 |a Chunga, Paul 
700 1 |a Levin, Ann 
700 1 |a Morgan, Win 
700 1 |a Lambach, Philipp 
700 1 |a Bhat, Niranjan 
700 1 |a Neuzil, Kathleen M 
700 1 |a Ortiz, Justin R 
700 1 |a Hutubessy, Raymond 
773 0 |t PLoS One  |g vol. 12, no. 12 (Dec 2017), p. e0190006 
786 0 |d ProQuest  |t Health & Medical Collection 
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856 4 0 |3 Full Text  |u https://www.proquest.com/docview/1981045741/fulltext/embedded/7BTGNMKEMPT1V9Z2?source=fedsrch 
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