Mediation and mechanism

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Publicado en:European Journal of Epidemiology vol. 24, no. 5 (May 2009), p. 217-224
Autor principal: Vanderweele, Tyler J
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Springer Nature B.V.
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Acceso en línea:Citation/Abstract
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100 1 |a Vanderweele, Tyler J 
245 1 |a Mediation and mechanism 
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513 |a Journal Article 
520 3 |a The concepts of mediation and mechanism are contrasted and logical implications holding between theses two concepts are described. The concept of mediation can be formalized using counterfactual definitions of indirect effects; the concept of mechanism can be formalized within the sufficient cause framework. It is shown that both concepts can be illustrated using a single causal diagram. It is also shown that mediation implies mechanism but mechanism need not imply mediation. Discussion is given regarding how the distinction between "statistical causality" and "mechanistic causality" is blurred by recent work in causal inference concerning methods for testing for mediation and mechanism. [PUBLICATION ABSTRACT]   The concepts of mediation and mechanism are contrasted and logical implications holding between theses two concepts are described. The concept of mediation can be formalized using counterfactual definitions of indirect effects; the concept of mechanism can be formalized within the sufficient cause framework. It is shown that both concepts can be illustrated using a single causal diagram. It is also shown that mediation implies mechanism but mechanism need not imply mediation. Discussion is given regarding how the distinction between "statistical causality" and "mechanistic causality" is blurred by recent work in causal inference concerning methods for testing for mediation and mechanism. 
650 1 2 |a Causality 
650 1 2 |a Effect Modifier, Epidemiologic 
650 2 2 |a Environmental Exposure 
650 1 2 |a Epidemiologic Methods 
650 2 2 |a Humans 
650 2 2 |a Models, Statistical 
650 1 2 |a Risk Assessment  |x methods 
653 |a Research methodology 
653 |a Epidemiology 
653 |a Social 
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