Residential exposure to electromagnetic fields and childhood leukaemia: A meta-analysis

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Εκδόθηκε σε:World Health Organization. Bulletin of the World Health Organization vol. 77, no. 11 (1999), p. 906-915
Κύριος συγγραφέας: Angelillo, I F
Άλλοι συγγραφείς: Villari, P
Έκδοση:
World Health Organization
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100 1 |a Angelillo, I F 
245 1 |a Residential exposure to electromagnetic fields and childhood leukaemia: A meta-analysis 
260 |b World Health Organization  |c 1999 
513 |a Journal Article 
520 3 |a Although individual epidemiological investigations have suggested associations between residential exposure to electromagnetic fields (EMFs) and childhood leukaemia, overall the findings have been inconclusive. Several of these studies do, however, lend themselves to application of the meta-analysis technique. For this purpose we carried out searches using MEDLINE and other sources, and 14 case-control studies and one cohort study were identified and evaluated for epidemiological quality and included in the meta-analysis. Relative risk estimates were extracted from each of the studies and pooled. Separate meta-analyses were performed on the basis of the assessed EMF exposure (wiring configuration codes, distance to power distribution equipment, spot and 24-h measures of magnetic field strength (magnetic flux density) and calculated magnetic field). The meta-analysis based on wiring configuration codes yielded a pooled relative risk estimate of 1.46 (95% confidence interval (CI) = 1.05-2.04, P = 0.024) and for that for exposure to 24-h measurements of magnetic fields, 1.59 (95% CI = 1.14-2.22, P = 0.006), indicating a potential effect of residential EMF exposure on childhood leukaemia. In most cases, lower risk estimates were obtained by pooling high-quality studies than pooling low-quality studies. There appears to be a clear trend for more recent studies to be of higher quality. Enough evidence exists to conclude that dismissing concerns about residential EMFs and childhood leukaemia is unwarranted. Additional high-quality epidemiological studies incorporating comparable measures for both exposure and outcomes are, however, needed to confirm these findings and, should they prove to be true, the case options for minimizing exposure should be thoroughly investigated to provide definitive answers for policy-makers. 
650 2 2 |a Child 
650 1 2 |a Electromagnetic Fields  |x adverse effects 
650 1 2 |a Environmental Exposure  |x adverse effects 
650 2 2 |a Environmental Exposure  |x analysis 
650 2 2 |a Epidemiologic Research Design 
650 2 2 |a Epidemiologic Studies 
650 2 2 |a Humans 
650 1 2 |a Leukemia, Radiation-Induced  |x epidemiology 
650 1 2 |a Leukemia, Radiation-Induced  |x etiology 
650 2 2 |a Radiation Monitoring 
650 1 2 |a Residence Characteristics  |x statistics & numerical data 
650 2 2 |a Risk 
650 2 2 |a Risk Factors 
650 2 2 |a Sensitivity & Specificity 
653 |a Methods 
653 |a Codes 
653 |a Investigations 
653 |a Leukemia 
653 |a Electromagnetism 
653 |a Quality 
653 |a Magnetic fields 
653 |a Meta-analysis 
653 |a Cohort analysis 
653 |a Exposure 
653 |a Analysis 
653 |a Electromagnetic waves 
653 |a Childhood 
653 |a Equipment 
653 |a Policy making 
653 |a Measures 
653 |a Epidemiology 
653 |a Social 
700 1 |a Villari, P 
773 0 |t World Health Organization. Bulletin of the World Health Organization  |g vol. 77, no. 11 (1999), p. 906-915 
786 0 |d ProQuest  |t ABI/INFORM Global 
856 4 1 |3 Citation/Abstract  |u https://www.proquest.com/docview/229686585/abstract/embedded/L8HZQI7Z43R0LA5T?source=fedsrch 
856 4 0 |3 Full Text + Graphics  |u https://www.proquest.com/docview/229686585/fulltextwithgraphics/embedded/L8HZQI7Z43R0LA5T?source=fedsrch 
856 4 0 |3 Full Text - PDF  |u https://www.proquest.com/docview/229686585/fulltextPDF/embedded/L8HZQI7Z43R0LA5T?source=fedsrch