Comparison between Three Techniques for Determining Glomerular Filtration Rates: 99mTc-Diethylene Triamine Penta-Acetic Acid Renography, Double Plasma Sampling Method, and Single Plasma Sampling Method in Vietnamese Patients
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| Yayımlandı: | Indian Journal of Nuclear Medicine : IJNM vol. 36, no. 3 (Jul 2021), p. 300 |
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| Yazar: | |
| Diğer Yazarlar: | , , , |
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Medknow Publications & Media Pvt. Ltd.
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| Online Erişim: | Citation/Abstract Full text outside of ProQuest |
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| 001 | 2576808210 | ||
| 003 | UK-CbPIL | ||
| 022 | |a 0972-3919 | ||
| 022 | |a 0974-0244 | ||
| 024 | 7 | |a 10.4103/ijnm.ijnm_240_20 |2 doi | |
| 035 | |a 2576808210 | ||
| 045 | 2 | |b d20210701 |b d20210731 | |
| 084 | |a 129519 |2 nlm | ||
| 100 | 1 | |a Thang Quoc |u Department of Radiology, Nuclear Medicine Unit, Vinmec International Hospital, Hanoi | |
| 245 | 1 | |a Comparison between Three Techniques for Determining Glomerular Filtration Rates: <sup>99m</sup>Tc-Diethylene Triamine Penta-Acetic Acid Renography, Double Plasma Sampling Method, and Single Plasma Sampling Method in Vietnamese Patients | |
| 260 | |b Medknow Publications & Media Pvt. Ltd. |c Jul 2021 | ||
| 513 | |a Journal Article | ||
| 520 | 3 | |a Glomerular filtration rate (GFR) is an important indicator of renal function. Many methods have been developed to determine GFR in clinical examinations. This study aims to correlate between radionuclide plasma sampling methods (single and double blood samples, in vitro methods) and in vivo Gate's method using 99mTc-diethylene triamine penta-acetic acid (99mTc-DTPA) renography. Materials and Methods: 43 patients underwent this study, including 31 renal donors (Group 1) and 12 patients with obstructive uropathy (Group 2). All patients were administered with a range of 5–7 mCi of 99mTc-DTPA. Then, renography performed simultaneously after injection and GFR calculation followed by Gate's method. Blood samples were collected at 60- and 120-min postinjection, samples were counted by a thyroid uptake system, and GFR was calculated using a single plasma sample method (SPSM) and a double plasma sample method (DPSM). Results: The mean GFRs calculated by Gate's method in Groups 1 and 2 were 85.8 ± 18.2 ml/min and 118.4 ± 13.9 ml/min, respectively. Meanwhile, using the in vitro blood sampling methods (DPSM and SPSM), the mean GFRs in Group 1 were 73.8 ± 15.4 ml/min and 56.4 ± 20.9 ml/min, respectively, and in Group 2 were 116.8 ± 12.9 ml/min and 106.3 ± 18.5 ml/min, respectively. There is a high correlation between Gate's method and DPSM in two groups (r = 0.86 and 0.72, respectively), and a moderate correlation was found between Gate's method and SPSM in both groups (r = 0.49 and r = 0.37, respectively). The two in vitro methods (DPSM and SPSM) revealed that moderate correlation in both groups (r = 0.74 and r = 0.67, respectively) was observed. Conclusion: Renography is a simple method but considered inaccurate for GFR determination. However, in vitro plasma sampling is rarely used in Vietnam. In this study, Gate's method correlated well with DPSM and tended to overestimate GFR. Further, the in vitro methods can be applied to correct the in vivo method as a confirmatory test in some cases. | |
| 653 | |a Renal function | ||
| 653 | |a In vitro methods and tests | ||
| 653 | |a Plasma | ||
| 653 | |a Methods | ||
| 653 | |a Mathematical analysis | ||
| 653 | |a Diethylene triamine | ||
| 653 | |a In vivo methods and tests | ||
| 653 | |a Blood | ||
| 653 | |a Sampling methods | ||
| 653 | |a Acetic acid | ||
| 653 | |a Radioisotopes | ||
| 700 | 1 | |a Kim, Nguyen Thi |u Department of Nuclear Medicine, 108 Military Central Hospital, Hanoi | |
| 700 | 1 | |a Dang, Tung |u Department of Radiology, Nuclear Medicine Unit, Vinmec International Hospital, Hanoi | |
| 700 | 1 | |a Xuan, Huy |u Drug Design and Pharmacology, Faculty of Pharmacy, PHENIKAA University; Drug Design and Pharmacology, PHENIKAA Institute for Advanced Study, PHENIKAA University, Hanoi | |
| 700 | 1 | |a Truong Tung |u Drug Design and Pharmacology, Faculty of Pharmacy, PHENIKAA University; Drug Design and Pharmacology, PHENIKAA Institute for Advanced Study, PHENIKAA University, Hanoi | |
| 773 | 0 | |t Indian Journal of Nuclear Medicine : IJNM |g vol. 36, no. 3 (Jul 2021), p. 300 | |
| 786 | 0 | |d ProQuest |t Health & Medical Collection | |
| 856 | 4 | 1 | |3 Citation/Abstract |u https://www.proquest.com/docview/2576808210/abstract/embedded/H09TXR3UUZB2ISDL?source=fedsrch |
| 856 | 4 | 0 | |3 Full text outside of ProQuest |u http://www.ijnm.in/article.asp?issn=0972-3919;year=2021;volume=36;issue=3;spage=300;epage=303;aulast=Quoc |