कवर छवि

A Novel Multi-Dimensional Clinical Response Index Dedicated to Improving Global Assessment of Pain in Patients with Persistent Spinal Pain Syndrome after Spinal Surgery, Based on a Real-Life Prospective Multicentric Study (PREDIBACK) and Machine Learning Techniques

में बचाया:
में प्रकाशित:Journal of Clinical Medicine vol. 10, no. 21 (2021), p. 4910
मुख्य लेखक: Rigoard, Philippe
अन्य लेखक: Ounajim, Amine, Goudman, Lisa, Pierre-Yves, Louis, Slaoui, Yousri, Roulaud, Manuel, Naiditch, Nicolas, Bouche, Bénédicte, Page, Philippe, Lorgeoux, Bertille, Baron, Sandrine, Charrier, Elodie, Poupin, Laure, Rannou, Delphine, Géraldine Brumauld de Montgazon, Roy-Moreau, Brigitte, Grimaud, Nelly, Adjali, Nihel, Nivole, Kevin, Many, Mathilde, Romain, David, Wood, Chantal, Rigoard, Raphael, Moens, Maarten, Billot, Maxime
प्रकाशित:
MDPI AG
विषय:
Patients
Machine learning
Quality of life
Pain
Spinal cord
Back surgery
Questionnaires
Anxiety
Artificial intelligence
ऑनलाइन पहुंच:Citation/Abstract
Full Text + Graphics
Full Text - PDF
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024 7 |a 10.3390/jcm10214910  |2 doi 
035 |a 2596035514 
045 2 |b d20210101  |b d20211231 
100 1 |a Rigoard, Philippe  |u PRISMATICS Lab (Predictive Research in Spine/Neuromodulation Management and Thoracic Innovation/Cardiac Surgery), Poitiers University Hospital, 86021 Poitiers, France; <email>Amine.OUNAJIM@chu-poitiers.fr</email> (A.O.); <email>Manuel.ROULAUD@chu-poitiers.fr</email> (M.R.); <email>nicolas.naiditch@gmail.com</email> (N.N.); <email>dr.bouche@gmail.com</email> (B.B.); <email>Bertille.LORGEOUX@chu-poitiers.fr</email> (B.L.); <email>sandrine.baron@chu-poitiers.fr</email> (S.B.); <email>Nihel.adjali@chu-poitiers.fr</email> (N.A.); <email>Kevin.NIVOLE@chu-poitiers.fr</email> (K.N.); <email>mathilde.many@chu-poitiers.fr</email> (M.M.); <email>romain-david@hotmail.fr</email> (R.D.); <email>chantalwood@orange.fr</email> (C.W.); <email>Maxime.BILLOT@chu-poitiers.fr</email> (M.B.); Department of Spine Surgery & Neuromodulation, Poitiers University Hospital, 86021 Poitiers, France; <email>Philippe.PAGE@chu-poitiers.fr</email>; Pprime Institute UPR 3346, CNRS, ISAE-ENSMA, University of Poitiers, 86360 Chasseneuil-du-Poitou, France 
245 1 |a A Novel Multi-Dimensional Clinical Response Index Dedicated to Improving Global Assessment of Pain in Patients with Persistent Spinal Pain Syndrome after Spinal Surgery, Based on a Real-Life Prospective Multicentric Study (PREDIBACK) and Machine Learning Techniques 
260 |b MDPI AG  |c 2021 
513 |a Journal Article 
520 3 |a The multidimensionality of chronic pain forces us to look beyond isolated assessment such as pain intensity, which does not consider multiple key parameters, particularly in post-operative Persistent Spinal Pain Syndrome (PSPS-T2) patients. Our ambition was to produce a novel Multi-dimensional Clinical Response Index (MCRI), including not only pain intensity but also functional capacity, anxiety-depression, quality of life and quantitative pain mapping, the objective being to achieve instantaneous assessment using machine learning techniques. Two hundred PSPS-T2 patients were enrolled in the real-life observational prospective PREDIBACK study with 12-month follow-up and received various treatments. From a multitude of questionnaires/scores, specific items were combined, as exploratory factor analyses helped to create a single composite MCRI; using pairwise correlations between measurements, it appeared to more accurately represent all pain dimensions than any previous classical score. It represented the best compromise among all existing indexes, showing the highest sensitivity/specificity related to Patient Global Impression of Change (PGIC). Novel composite indexes could help to refine pain assessment by informing the physician’s perception of patient condition on the basis of objective and holistic metrics, and also by providing new insights regarding therapy efficacy/patient outcome assessments, before ultimately being adapted to other pathologies. 
653 |a Patients 
653 |a Machine learning 
653 |a Quality of life 
653 |a Pain 
653 |a Spinal cord 
653 |a Back surgery 
653 |a Questionnaires 
653 |a Anxiety 
653 |a Artificial intelligence 
700 1 |a Ounajim, Amine  |u PRISMATICS Lab (Predictive Research in Spine/Neuromodulation Management and Thoracic Innovation/Cardiac Surgery), Poitiers University Hospital, 86021 Poitiers, France; <email>Amine.OUNAJIM@chu-poitiers.fr</email> (A.O.); <email>Manuel.ROULAUD@chu-poitiers.fr</email> (M.R.); <email>nicolas.naiditch@gmail.com</email> (N.N.); <email>dr.bouche@gmail.com</email> (B.B.); <email>Bertille.LORGEOUX@chu-poitiers.fr</email> (B.L.); <email>sandrine.baron@chu-poitiers.fr</email> (S.B.); <email>Nihel.adjali@chu-poitiers.fr</email> (N.A.); <email>Kevin.NIVOLE@chu-poitiers.fr</email> (K.N.); <email>mathilde.many@chu-poitiers.fr</email> (M.M.); <email>romain-david@hotmail.fr</email> (R.D.); <email>chantalwood@orange.fr</email> (C.W.); <email>Maxime.BILLOT@chu-poitiers.fr</email> (M.B.); Laboratoire de Mathématiques et Applications UMR 7348, CNRS, University of Poitiers, 86073 Poitiers, France; <email>yousri.slaoui@math.univ-poitiers.fr</email> 
700 1 |a Goudman, Lisa  |u Department of Neurosurgery, Universitair Ziekenhuis Brussel, 1090 Brussels, Belgium; <email>lisa.goudman@gmail.com</email> (L.G.); <email>mtmoens@gmail.com</email> (M.M.); STIMULUS Research Group, Vrije Universiteit Brussel, 1090 Brussels, Belgium 
700 1 |a Pierre-Yves, Louis  |u AgroSup Dijon, PAM UMR 02.102, Université Bourgogne Franche-Comté, 21000 Dijon, France; <email>pierre-yves.louis@agrosupdijon.fr</email>; Institut de Mathématiques de Bourgogne, UMR 5584 CNRS, Université Bourgogne Franche-Comté, 21000 Dijon, France 
700 1 |a Slaoui, Yousri  |u Laboratoire de Mathématiques et Applications UMR 7348, CNRS, University of Poitiers, 86073 Poitiers, France; <email>yousri.slaoui@math.univ-poitiers.fr</email> 
700 1 |a Roulaud, Manuel  |u PRISMATICS Lab (Predictive Research in Spine/Neuromodulation Management and Thoracic Innovation/Cardiac Surgery), Poitiers University Hospital, 86021 Poitiers, France; <email>Amine.OUNAJIM@chu-poitiers.fr</email> (A.O.); <email>Manuel.ROULAUD@chu-poitiers.fr</email> (M.R.); <email>nicolas.naiditch@gmail.com</email> (N.N.); <email>dr.bouche@gmail.com</email> (B.B.); <email>Bertille.LORGEOUX@chu-poitiers.fr</email> (B.L.); <email>sandrine.baron@chu-poitiers.fr</email> (S.B.); <email>Nihel.adjali@chu-poitiers.fr</email> (N.A.); <email>Kevin.NIVOLE@chu-poitiers.fr</email> (K.N.); <email>mathilde.many@chu-poitiers.fr</email> (M.M.); <email>romain-david@hotmail.fr</email> (R.D.); <email>chantalwood@orange.fr</email> (C.W.); <email>Maxime.BILLOT@chu-poitiers.fr</email> (M.B.) 
700 1 |a Naiditch, Nicolas  |u PRISMATICS Lab (Predictive Research in Spine/Neuromodulation Management and Thoracic Innovation/Cardiac Surgery), Poitiers University Hospital, 86021 Poitiers, France; <email>Amine.OUNAJIM@chu-poitiers.fr</email> (A.O.); <email>Manuel.ROULAUD@chu-poitiers.fr</email> (M.R.); <email>nicolas.naiditch@gmail.com</email> (N.N.); <email>dr.bouche@gmail.com</email> (B.B.); <email>Bertille.LORGEOUX@chu-poitiers.fr</email> (B.L.); <email>sandrine.baron@chu-poitiers.fr</email> (S.B.); <email>Nihel.adjali@chu-poitiers.fr</email> (N.A.); <email>Kevin.NIVOLE@chu-poitiers.fr</email> (K.N.); <email>mathilde.many@chu-poitiers.fr</email> (M.M.); <email>romain-david@hotmail.fr</email> (R.D.); <email>chantalwood@orange.fr</email> (C.W.); <email>Maxime.BILLOT@chu-poitiers.fr</email> (M.B.) 
700 1 |a Bouche, Bénédicte  |u PRISMATICS Lab (Predictive Research in Spine/Neuromodulation Management and Thoracic Innovation/Cardiac Surgery), Poitiers University Hospital, 86021 Poitiers, France; <email>Amine.OUNAJIM@chu-poitiers.fr</email> (A.O.); <email>Manuel.ROULAUD@chu-poitiers.fr</email> (M.R.); <email>nicolas.naiditch@gmail.com</email> (N.N.); <email>dr.bouche@gmail.com</email> (B.B.); <email>Bertille.LORGEOUX@chu-poitiers.fr</email> (B.L.); <email>sandrine.baron@chu-poitiers.fr</email> (S.B.); <email>Nihel.adjali@chu-poitiers.fr</email> (N.A.); <email>Kevin.NIVOLE@chu-poitiers.fr</email> (K.N.); <email>mathilde.many@chu-poitiers.fr</email> (M.M.); <email>romain-david@hotmail.fr</email> (R.D.); <email>chantalwood@orange.fr</email> (C.W.); <email>Maxime.BILLOT@chu-poitiers.fr</email> (M.B.); Department of Spine Surgery & Neuromodulation, Poitiers University Hospital, 86021 Poitiers, France; <email>Philippe.PAGE@chu-poitiers.fr</email> 
700 1 |a Page, Philippe  |u Department of Spine Surgery & Neuromodulation, Poitiers University Hospital, 86021 Poitiers, France; <email>Philippe.PAGE@chu-poitiers.fr</email> 
700 1 |a Lorgeoux, Bertille  |u PRISMATICS Lab (Predictive Research in Spine/Neuromodulation Management and Thoracic Innovation/Cardiac Surgery), Poitiers University Hospital, 86021 Poitiers, France; <email>Amine.OUNAJIM@chu-poitiers.fr</email> (A.O.); <email>Manuel.ROULAUD@chu-poitiers.fr</email> (M.R.); <email>nicolas.naiditch@gmail.com</email> (N.N.); <email>dr.bouche@gmail.com</email> (B.B.); <email>Bertille.LORGEOUX@chu-poitiers.fr</email> (B.L.); <email>sandrine.baron@chu-poitiers.fr</email> (S.B.); <email>Nihel.adjali@chu-poitiers.fr</email> (N.A.); <email>Kevin.NIVOLE@chu-poitiers.fr</email> (K.N.); <email>mathilde.many@chu-poitiers.fr</email> (M.M.); <email>romain-david@hotmail.fr</email> (R.D.); <email>chantalwood@orange.fr</email> (C.W.); <email>Maxime.BILLOT@chu-poitiers.fr</email> (M.B.) 
700 1 |a Baron, Sandrine  |u PRISMATICS Lab (Predictive Research in Spine/Neuromodulation Management and Thoracic Innovation/Cardiac Surgery), Poitiers University Hospital, 86021 Poitiers, France; <email>Amine.OUNAJIM@chu-poitiers.fr</email> (A.O.); <email>Manuel.ROULAUD@chu-poitiers.fr</email> (M.R.); <email>nicolas.naiditch@gmail.com</email> (N.N.); <email>dr.bouche@gmail.com</email> (B.B.); <email>Bertille.LORGEOUX@chu-poitiers.fr</email> (B.L.); <email>sandrine.baron@chu-poitiers.fr</email> (S.B.); <email>Nihel.adjali@chu-poitiers.fr</email> (N.A.); <email>Kevin.NIVOLE@chu-poitiers.fr</email> (K.N.); <email>mathilde.many@chu-poitiers.fr</email> (M.M.); <email>romain-david@hotmail.fr</email> (R.D.); <email>chantalwood@orange.fr</email> (C.W.); <email>Maxime.BILLOT@chu-poitiers.fr</email> (M.B.) 
700 1 |a Charrier, Elodie  |u Pain Evaluation and Treatment Centre, Poitiers University Hospital, 86021 Poitiers, France; <email>Elodie.CHARRIER@chu-poitiers.fr</email> (E.C.); <email>laure.poupin@chu-poitiers.fr</email> (L.P.); <email>delphine.rannou@chu-poitiers.fr</email> (D.R.) 
700 1 |a Poupin, Laure  |u Pain Evaluation and Treatment Centre, Poitiers University Hospital, 86021 Poitiers, France; <email>Elodie.CHARRIER@chu-poitiers.fr</email> (E.C.); <email>laure.poupin@chu-poitiers.fr</email> (L.P.); <email>delphine.rannou@chu-poitiers.fr</email> (D.R.) 
700 1 |a Rannou, Delphine  |u Pain Evaluation and Treatment Centre, Poitiers University Hospital, 86021 Poitiers, France; <email>Elodie.CHARRIER@chu-poitiers.fr</email> (E.C.); <email>laure.poupin@chu-poitiers.fr</email> (L.P.); <email>delphine.rannou@chu-poitiers.fr</email> (D.R.) 
700 1 |a Géraldine Brumauld de Montgazon  |u Pain Evaluation and Treatment Centre, La Rochelle Hospital, 17000 La Rochelle, France; <email>Geraldine.DEMONTGAZON@ght-atlantique17.fr</email> 
700 1 |a Roy-Moreau, Brigitte  |u Pain Evaluation and Treatment Centre, Nord Deux-Sèvres Hospital, 79000 Niort, France; <email>Roy-Moreau.Brigitte@chnds.fr</email> 
700 1 |a Grimaud, Nelly  |u Pain Evaluation and Treatment Centre, Centre Clinical Elsan, 16800 Soyaux, France; <email>ngrimaud@centre-clinical.fr</email> 
700 1 |a Adjali, Nihel  |u PRISMATICS Lab (Predictive Research in Spine/Neuromodulation Management and Thoracic Innovation/Cardiac Surgery), Poitiers University Hospital, 86021 Poitiers, France; <email>Amine.OUNAJIM@chu-poitiers.fr</email> (A.O.); <email>Manuel.ROULAUD@chu-poitiers.fr</email> (M.R.); <email>nicolas.naiditch@gmail.com</email> (N.N.); <email>dr.bouche@gmail.com</email> (B.B.); <email>Bertille.LORGEOUX@chu-poitiers.fr</email> (B.L.); <email>sandrine.baron@chu-poitiers.fr</email> (S.B.); <email>Nihel.adjali@chu-poitiers.fr</email> (N.A.); <email>Kevin.NIVOLE@chu-poitiers.fr</email> (K.N.); <email>mathilde.many@chu-poitiers.fr</email> (M.M.); <email>romain-david@hotmail.fr</email> (R.D.); <email>chantalwood@orange.fr</email> (C.W.); <email>Maxime.BILLOT@chu-poitiers.fr</email> (M.B.) 
700 1 |a Nivole, Kevin  |u PRISMATICS Lab (Predictive Research in Spine/Neuromodulation Management and Thoracic Innovation/Cardiac Surgery), Poitiers University Hospital, 86021 Poitiers, France; <email>Amine.OUNAJIM@chu-poitiers.fr</email> (A.O.); <email>Manuel.ROULAUD@chu-poitiers.fr</email> (M.R.); <email>nicolas.naiditch@gmail.com</email> (N.N.); <email>dr.bouche@gmail.com</email> (B.B.); <email>Bertille.LORGEOUX@chu-poitiers.fr</email> (B.L.); <email>sandrine.baron@chu-poitiers.fr</email> (S.B.); <email>Nihel.adjali@chu-poitiers.fr</email> (N.A.); <email>Kevin.NIVOLE@chu-poitiers.fr</email> (K.N.); <email>mathilde.many@chu-poitiers.fr</email> (M.M.); <email>romain-david@hotmail.fr</email> (R.D.); <email>chantalwood@orange.fr</email> (C.W.); <email>Maxime.BILLOT@chu-poitiers.fr</email> (M.B.) 
700 1 |a Many, Mathilde  |u PRISMATICS Lab (Predictive Research in Spine/Neuromodulation Management and Thoracic Innovation/Cardiac Surgery), Poitiers University Hospital, 86021 Poitiers, France; <email>Amine.OUNAJIM@chu-poitiers.fr</email> (A.O.); <email>Manuel.ROULAUD@chu-poitiers.fr</email> (M.R.); <email>nicolas.naiditch@gmail.com</email> (N.N.); <email>dr.bouche@gmail.com</email> (B.B.); <email>Bertille.LORGEOUX@chu-poitiers.fr</email> (B.L.); <email>sandrine.baron@chu-poitiers.fr</email> (S.B.); <email>Nihel.adjali@chu-poitiers.fr</email> (N.A.); <email>Kevin.NIVOLE@chu-poitiers.fr</email> (K.N.); <email>mathilde.many@chu-poitiers.fr</email> (M.M.); <email>romain-david@hotmail.fr</email> (R.D.); <email>chantalwood@orange.fr</email> (C.W.); <email>Maxime.BILLOT@chu-poitiers.fr</email> (M.B.) 
700 1 |a Romain, David  |u PRISMATICS Lab (Predictive Research in Spine/Neuromodulation Management and Thoracic Innovation/Cardiac Surgery), Poitiers University Hospital, 86021 Poitiers, France; <email>Amine.OUNAJIM@chu-poitiers.fr</email> (A.O.); <email>Manuel.ROULAUD@chu-poitiers.fr</email> (M.R.); <email>nicolas.naiditch@gmail.com</email> (N.N.); <email>dr.bouche@gmail.com</email> (B.B.); <email>Bertille.LORGEOUX@chu-poitiers.fr</email> (B.L.); <email>sandrine.baron@chu-poitiers.fr</email> (S.B.); <email>Nihel.adjali@chu-poitiers.fr</email> (N.A.); <email>Kevin.NIVOLE@chu-poitiers.fr</email> (K.N.); <email>mathilde.many@chu-poitiers.fr</email> (M.M.); <email>romain-david@hotmail.fr</email> (R.D.); <email>chantalwood@orange.fr</email> (C.W.); <email>Maxime.BILLOT@chu-poitiers.fr</email> (M.B.); Physical and Rehabilitation Medicine Unit, Poitiers University Hospital, University of Poitiers, 86021 Poitiers, France 
700 1 |a Wood, Chantal  |u PRISMATICS Lab (Predictive Research in Spine/Neuromodulation Management and Thoracic Innovation/Cardiac Surgery), Poitiers University Hospital, 86021 Poitiers, France; <email>Amine.OUNAJIM@chu-poitiers.fr</email> (A.O.); <email>Manuel.ROULAUD@chu-poitiers.fr</email> (M.R.); <email>nicolas.naiditch@gmail.com</email> (N.N.); <email>dr.bouche@gmail.com</email> (B.B.); <email>Bertille.LORGEOUX@chu-poitiers.fr</email> (B.L.); <email>sandrine.baron@chu-poitiers.fr</email> (S.B.); <email>Nihel.adjali@chu-poitiers.fr</email> (N.A.); <email>Kevin.NIVOLE@chu-poitiers.fr</email> (K.N.); <email>mathilde.many@chu-poitiers.fr</email> (M.M.); <email>romain-david@hotmail.fr</email> (R.D.); <email>chantalwood@orange.fr</email> (C.W.); <email>Maxime.BILLOT@chu-poitiers.fr</email> (M.B.) 
700 1 |a Rigoard, Raphael  |u CEA Cadarache, Département de Support Technique et Gestion, Service des Technologies de l’Information et de la Communication, 13108 Saint-Paul-Lez-Durance, France; <email>cydran@gmail.com</email> 
700 1 |a Moens, Maarten  |u Department of Neurosurgery, Universitair Ziekenhuis Brussel, 1090 Brussels, Belgium; <email>lisa.goudman@gmail.com</email> (L.G.); <email>mtmoens@gmail.com</email> (M.M.); STIMULUS Research Group, Vrije Universiteit Brussel, 1090 Brussels, Belgium 
700 1 |a Billot, Maxime  |u PRISMATICS Lab (Predictive Research in Spine/Neuromodulation Management and Thoracic Innovation/Cardiac Surgery), Poitiers University Hospital, 86021 Poitiers, France; <email>Amine.OUNAJIM@chu-poitiers.fr</email> (A.O.); <email>Manuel.ROULAUD@chu-poitiers.fr</email> (M.R.); <email>nicolas.naiditch@gmail.com</email> (N.N.); <email>dr.bouche@gmail.com</email> (B.B.); <email>Bertille.LORGEOUX@chu-poitiers.fr</email> (B.L.); <email>sandrine.baron@chu-poitiers.fr</email> (S.B.); <email>Nihel.adjali@chu-poitiers.fr</email> (N.A.); <email>Kevin.NIVOLE@chu-poitiers.fr</email> (K.N.); <email>mathilde.many@chu-poitiers.fr</email> (M.M.); <email>romain-david@hotmail.fr</email> (R.D.); <email>chantalwood@orange.fr</email> (C.W.); <email>Maxime.BILLOT@chu-poitiers.fr</email> (M.B.) 
773 0 |t Journal of Clinical Medicine  |g vol. 10, no. 21 (2021), p. 4910 
786 0 |d ProQuest  |t Health & Medical Collection 
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