IDDF2022-ABS-0238 Colorectal adenomas in the young: retrospective data from a tertiary hospital in manila, Philippines

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Izdano u:Gut vol. 71, no. Suppl 2 (Sep 2022), p. A169
Glavni autor: Joseph Erwin Dumagpi
Daljnji autori: Gopez-Cervantes, Juliet, Nikko Theodore Raymundo, Lin, Tim Lawrence
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BMJ Publishing Group LTD
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LEADER 00000nab a2200000uu 4500
001 2711022908
003 UK-CbPIL
022 |a 0017-5749 
022 |a 1468-3288 
024 7 |a 10.1136/gutjnl-2022-IDDF.236  |2 doi 
035 |a 2711022908 
045 2 |b d20220901  |b d20220930 
084 |a 270534  |2 nlm 
100 1 |a Joseph Erwin Dumagpi 
245 1 |a IDDF2022-ABS-0238 Colorectal adenomas in the young: retrospective data from a tertiary hospital in manila, Philippines 
260 |b BMJ Publishing Group LTD  |c Sep 2022 
513 |a Journal Article 
520 3 |a BackgroundThe incidence and mortality of colorectal cancer (CRC) are increasing among the young. Adenoma detection, removal and subsequent endoscopic surveillance may modify the risk of CRC before 50 years of age. This study aims to evaluate the situation of colorectal adenoma detection in Filipino patients less than 50 years of age.MethodsThis is a retrospective, descriptive study with 6211 patients less than 50 years of age who underwent colonoscopy. The endoscopy databank from January 1, 2010 until December 31, 2020 of the Institute of Digestive and Liver Diseases of St. Luke’s Medical Center Global City was used to identify cases and obtain data for this study.ResultsOverall, 6211 less than 50 years of age were included in this study. The mean age of the cohort was 43 years old; 58% were males. Family history of colorectal cancer was present in 34.8%. Asymptomatic screening was the main indication for colonoscopy.Overall, 2103 patients (33.9%) were found to have polyps. Hyperplastic polyps were the most common (25.1%), followed by adenomas (9%). Fourteen patients who were found to have hyperplastic polyp were also found to have concomitant adenomas. Advanced neoplasm was seen in 252 patients (4.1%), with 23 of these patients having concomitant adenomas.Polyps and advanced neoplasm were more likely seen among those aged 40–49 (60.1%). Among those with polyps in the 40–49 age group, hyperplastic polyps and adenomas were most common (42% and 14.1%, respectively). Advanced neoplasms were also most common in the 40–49 age group (14.1%).Polyps are more frequent in males (39.3%) compared to females. Hyperplastic polyps and advanced neoplasms were likewise common in males (26.4% and 4.4%, respectively). Adenomas were more common in females (9.3%).ConclusionsWith the limitations of this study, we found that the overall prevalence of adenomas and advanced neoplasm among those aged less than 50 years to be 9% and 4.1% respectively. Increasing age and sex were associated with the development of adenomas. More research on risk factors, including whether detection, removal, and surveillance of adenomas in the young have the potential to impact early-onset colorectal cancer incidence and mortality. 
651 4 |a Philippines 
651 4 |a Manila Philippines 
653 |a Males 
653 |a Adenoma 
653 |a Polyps 
653 |a Colonoscopy 
653 |a Endoscopy 
653 |a Mortality 
653 |a Risk factors 
653 |a Age 
653 |a Colorectal carcinoma 
653 |a Age groups 
653 |a Liver diseases 
653 |a Colorectal cancer 
653 |a Surveillance 
653 |a Tumors 
653 |a Patients 
700 1 |a Gopez-Cervantes, Juliet 
700 1 |a Nikko Theodore Raymundo 
700 1 |a Lin, Tim Lawrence 
773 0 |t Gut  |g vol. 71, no. Suppl 2 (Sep 2022), p. A169 
786 0 |d ProQuest  |t Science Database 
856 4 1 |3 Citation/Abstract  |u https://www.proquest.com/docview/2711022908/abstract/embedded/H09TXR3UUZB2ISDL?source=fedsrch 
856 4 0 |3 Full Text - PDF  |u https://www.proquest.com/docview/2711022908/fulltextPDF/embedded/H09TXR3UUZB2ISDL?source=fedsrch