A comparative study of short-term phonatory outcomes in primary cases of early glottic cancer treated with radiotherapy versus laser surgery

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Foilsithe in:The Egyptian Journal of Otolaryngology vol. 40, no. 1 (Dec 2024), p. 6
Príomhchruthaitheoir: Gupta, Devender Kumar
Rannpháirtithe: Ravunnikutty, Mahesh, Singh, Sanajeet Kumar, Chugh, Rajeev, Roy, Ravi, Goyal, Sunil, Swami, Himanshu, Patel, Bhaumik, Yadav, Sneha, Banger, Sween
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Springer Nature B.V.
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Rochtain ar líne:Citation/Abstract
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022 |a 1012-5574 
022 |a 2090-8539 
024 7 |a 10.1186/s43163-024-00565-w  |2 doi 
035 |a 2916273518 
045 2 |b d20241201  |b d20241231 
100 1 |a Gupta, Devender Kumar  |u Army Hospital Research and Referral, Department of ENT HNS, New Delhi, India (GRID:grid.428097.0) 
245 1 |a A comparative study of short-term phonatory outcomes in primary cases of early glottic cancer treated with radiotherapy versus laser surgery 
260 |b Springer Nature B.V.  |c Dec 2024 
513 |a Journal Article 
520 3 |a BackgroundEarly-stage glottic carcinomas can be treated with either laser surgery or radiotherapy. Both approaches have demonstrated similar cure rates. However, the question of which modality is superior in terms of voice outcomes remains a topic of debate.MethodsIn our study, we conducted a comparison of short-term phonatory outcomes in patients with primary early glottic cancer who underwent treatment using both modalities. We assessed these outcomes using videostroboscopy and voice analysis software at three time points: immediately following treatment, at 1 month, and at 3 months post-treatment.ResultsVoice analysis revealed that laser surgery had a more favorable immediate effect compared to radiotherapy in parameters such as jitter, shimmer, harmonics-to-noise ratio, and fundamental frequency. However, at the 3-month post-treatment mark, both treatment modalities demonstrated similar effects. Additionally, both modalities had comparable effects on maximum phonation time. Videostroboscopy observations showed that mucosal wave forms were more prominent immediately after laser surgery and gradually improved following radiotherapy. Furthermore, patients with incomplete glottic closure experienced recovery after both treatment modalities.ConclusionBased on the results, there are better outcomes immediately following LS compared to RT. However, after a 3-month period, the outcomes of both treatment modalities become comparable. The treating physicians must consider various factors such as complications, patient-specific considerations, treatment costs, and duration to make informed decisions. A personalized approach considering the individual patient’s circumstances is crucial in achieving optimal results in the management of T1 laryngeal cancer. 
653 |a Ostomy 
653 |a Histopathology 
653 |a Laser surgery 
653 |a Larynx 
653 |a Surgery 
653 |a Cancer therapies 
653 |a Radiation therapy 
653 |a Biopsy 
653 |a Laryngeal cancer 
700 1 |a Ravunnikutty, Mahesh  |u Army Hospital Research and Referral, Department of ENT HNS, New Delhi, India (GRID:grid.428097.0) 
700 1 |a Singh, Sanajeet Kumar  |u Army Hospital Research and Referral, Department of ENT HNS, New Delhi, India (GRID:grid.428097.0) 
700 1 |a Chugh, Rajeev  |u Army Hospital Research and Referral, Department of ENT HNS, New Delhi, India (GRID:grid.428097.0) 
700 1 |a Roy, Ravi  |u Army Hospital Research and Referral, Department of ENT HNS, New Delhi, India (GRID:grid.428097.0) 
700 1 |a Goyal, Sunil  |u Army Hospital Research and Referral, Department of ENT HNS, New Delhi, India (GRID:grid.428097.0) 
700 1 |a Swami, Himanshu  |u Army Hospital Research and Referral, Department of ENT HNS, New Delhi, India (GRID:grid.428097.0) 
700 1 |a Patel, Bhaumik  |u Army Hospital Research and Referral, Department of ENT HNS, New Delhi, India (GRID:grid.428097.0) 
700 1 |a Yadav, Sneha  |u Army Hospital Research and Referral, Department of ENT HNS, New Delhi, India (GRID:grid.428097.0) 
700 1 |a Banger, Sween  |u Army Hospital Research and Referral, Department of ENT HNS, New Delhi, India (GRID:grid.428097.0) 
773 0 |t The Egyptian Journal of Otolaryngology  |g vol. 40, no. 1 (Dec 2024), p. 6 
786 0 |d ProQuest  |t Health & Medical Collection 
856 4 1 |3 Citation/Abstract  |u https://www.proquest.com/docview/2916273518/abstract/embedded/7BTGNMKEMPT1V9Z2?source=fedsrch 
856 4 0 |3 Full Text  |u https://www.proquest.com/docview/2916273518/fulltext/embedded/7BTGNMKEMPT1V9Z2?source=fedsrch 
856 4 0 |3 Full Text - PDF  |u https://www.proquest.com/docview/2916273518/fulltextPDF/embedded/7BTGNMKEMPT1V9Z2?source=fedsrch