The time-locked neurodynamics of semantic processing in autism spectrum disorder: an EEG study

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Pubblicato in:Cognitive Neurodynamics vol. 16, no. 1 (Feb 2022), p. 43
Autore principale: Curl, Azilee
Altri autori: Coderre, Emily L.
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Springer Nature B.V.
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024 7 |a 10.1007/s11571-021-09697-8  |2 doi 
035 |a 2918680035 
045 2 |b d20220201  |b d20220228 
100 1 |a Curl, Azilee  |u University of Vermont, Department of Communication Sciences and Disorders, Burlington, USA (GRID:grid.59062.38) (ISNI:0000 0004 1936 7689) 
245 1 |a The time-locked neurodynamics of semantic processing in autism spectrum disorder: an EEG study 
260 |b Springer Nature B.V.  |c Feb 2022 
513 |a Journal Article 
520 3 |a Language processing is often an area of difficulty in Autism Spectrum Disorder (ASD). Semantic processing—the ability to add meaning to a stimulus—is thought to be especially affected in ASD. However, the neurological origin of these deficits, both structurally and temporally, have yet to be discovered. To further previous behavioral findings on language differences in ASD, the present study used an implicit semantic priming paradigm and electroencephalography (EEG) to compare the level of theta coherence throughout semantic processing, between typically developing (TD) and ASD participants. Theta coherence is an indication of synchronous EEG oscillations and was of particular interest due to its previous links with semantic processing. Theta coherence was analyzed in response to semantically related or unrelated pairs of words and pictures across bilateral short, medium, and long electrode connections. We found significant results across a variety of conditions, but most notably, we observed reduced coherence for language stimuli in the ASD group at a left fronto-parietal connection from 100 to 300 ms. This replicates previous findings of underconnectivity in left fronto-parietal language networks in ASD. Critically, the early time window of this underconnectivity, from 100 to 300 ms, suggests that impaired semantic processing of language in ASD may arise during pre-semantic processing, during the initial communication between lower-level linguistic processing and higher-level semantic processing. Our results suggest that language processing functions are unique in ASD compared to TD, and that subjects with ASD might rely on a temporally different language processing loop altogether. 
653 |a Language 
653 |a Oscillations 
653 |a Semantics 
653 |a EEG 
653 |a Autism 
653 |a Neurological diseases 
653 |a Reading comprehension 
653 |a Brain 
653 |a Electroencephalography 
653 |a Linguistics 
653 |a Information processing 
653 |a Windows (intervals) 
653 |a Natural language processing 
653 |a Coherence 
700 1 |a Coderre, Emily L.  |u University of Vermont, Department of Communication Sciences and Disorders, Burlington, USA (GRID:grid.59062.38) (ISNI:0000 0004 1936 7689) 
773 0 |t Cognitive Neurodynamics  |g vol. 16, no. 1 (Feb 2022), p. 43 
786 0 |d ProQuest  |t Health & Medical Collection 
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