Evaluation of Antimicrobial Properties, Cell Viability, and Metalloproteinase Activity of Bioceramic Endodontic Materials Used in Vital Pulp Therapy
Shranjeno v:
| izdano v: | Journal of Functional Biomaterials vol. 15, no. 3 (2024), p. 70 |
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| Glavni avtor: | |
| Drugi avtorji: | , , , , , , , , , |
| Izdano: |
MDPI AG
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| Teme: | |
| Online dostop: | Citation/Abstract Full Text + Graphics Full Text - PDF |
| Oznake: |
Brez oznak, prvi označite!
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MARC
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| 001 | 3003032013 | ||
| 003 | UK-CbPIL | ||
| 022 | |a 2079-4983 | ||
| 024 | 7 | |a 10.3390/jfb15030070 |2 doi | |
| 035 | |a 3003032013 | ||
| 045 | 2 | |b d20240101 |b d20241231 | |
| 084 | |a 231477 |2 nlm | ||
| 100 | 1 | |a Immich, Felipe |u Graduate Program in Dentistry, School of Dentistry, Federal University of Pelotas (UFPEL), Pelotas 96015-560, Brazil; <email>felipe.immich@ufpel.edu.br</email> (F.I.); <email>juliana.r.andrade@ufsc.br</email> (J.S.R.d.A.); <email>andressa.barboza@posgrad.ufsc.br</email> (A.d.S.B.); <email>adriana@ufpel.edu.br</email> (A.F.d.S.); <email>wellingtonl.fo@ufpel.edu.br</email> (W.L.d.O.d.R.); <email>piva@ufpel.edu.br</email> (E.P.) | |
| 245 | 1 | |a Evaluation of Antimicrobial Properties, Cell Viability, and Metalloproteinase Activity of Bioceramic Endodontic Materials Used in Vital Pulp Therapy | |
| 260 | |b MDPI AG |c 2024 | ||
| 513 | |a Journal Article | ||
| 520 | 3 | |a This study aimed to evaluate the antimicrobial properties, cell viability, and matrix metalloproteinase (MMP) inhibition capacity of several endodontic materials aimed at vital pulp therapy: Pro Root MTA®, EndoSequence®, Biodentine®, MTA Angelus®, TheraCal LC®, and BioC Repair®. The materials were prepared according to the manufacturer’s instructions. Antimicrobial tests were conducted using a microcosm biofilm model, cell viability was assessed using murine fibroblasts (L929), and MMP activity was analyzed through electrophoresis. The results showed that BioC Repair®, Biodentine®, and EndoSequence® exhibited similar antimicrobial properties, while MTA Angelus® and ProRoot MTA® had inferior results but were comparable to each other. In terms of cell viability, no significant differences were observed among the materials. EndoSequence® demonstrated the highest MMP inhibition capacity. In conclusion, BioC Repair®, Biodentine®, EndoSequence®, and TheraCal® showed better antimicrobial properties among the tested materials. The materials did not exhibit significant differences in terms of cytotoxicity. However, EndoSequence® displayed superior MMP inhibition capacity. | |
| 610 | 4 | |a Brasseler USA | |
| 651 | 4 | |a Brazil | |
| 651 | 4 | |a Basel Switzerland | |
| 651 | 4 | |a Switzerland | |
| 651 | 4 | |a United States--US | |
| 653 | |a Cytotoxicity | ||
| 653 | |a Endodontics | ||
| 653 | |a Silicones | ||
| 653 | |a Biofilms | ||
| 653 | |a Extracellular matrix | ||
| 653 | |a Matrix metalloproteinases | ||
| 653 | |a Radiation | ||
| 653 | |a Cell culture | ||
| 653 | |a Fibroblasts | ||
| 653 | |a Metalloproteinase | ||
| 653 | |a Bioceramics | ||
| 653 | |a Antimicrobial agents | ||
| 653 | |a Electrophoresis | ||
| 653 | |a Dental pulp | ||
| 653 | |a Matrix metalloproteinase | ||
| 653 | |a Dentistry | ||
| 653 | |a Cement | ||
| 653 | |a Cell viability | ||
| 653 | |a Enzymes | ||
| 653 | |a Variance analysis | ||
| 653 | |a Environmental | ||
| 700 | 1 | |a Durvalino de Oliveira |u Graduate Program in Dentistry, School of Dentistry, University of Cuiabá (UNIC), Cuiabá 78000-000, Brazil; <email>durvalinooliveira@gmail.com</email> (D.d.O.); <email>alvarohborges@gmail.com</email> (Á.H.B.) | |
| 700 | 1 | |a Juliana Silva Ribeiro de Andrade |u Graduate Program in Dentistry, School of Dentistry, Federal University of Pelotas (UFPEL), Pelotas 96015-560, Brazil; <email>felipe.immich@ufpel.edu.br</email> (F.I.); <email>juliana.r.andrade@ufsc.br</email> (J.S.R.d.A.); <email>andressa.barboza@posgrad.ufsc.br</email> (A.d.S.B.); <email>adriana@ufpel.edu.br</email> (A.F.d.S.); <email>wellingtonl.fo@ufpel.edu.br</email> (W.L.d.O.d.R.); <email>piva@ufpel.edu.br</email> (E.P.) | |
| 700 | 1 | |a Andressa da Silva Barboza |u Graduate Program in Dentistry, School of Dentistry, Federal University of Pelotas (UFPEL), Pelotas 96015-560, Brazil; <email>felipe.immich@ufpel.edu.br</email> (F.I.); <email>juliana.r.andrade@ufsc.br</email> (J.S.R.d.A.); <email>andressa.barboza@posgrad.ufsc.br</email> (A.d.S.B.); <email>adriana@ufpel.edu.br</email> (A.F.d.S.); <email>wellingtonl.fo@ufpel.edu.br</email> (W.L.d.O.d.R.); <email>piva@ufpel.edu.br</email> (E.P.) | |
| 700 | 1 | |a Cuevas-Suárez, Carlos Enrique |u Graduate Program in Dentistry, School on Dentistry, Autonomous University of State of Hidalgo, San Agustín Tlaxiaca, Pachuca de Soto 42080, Mexico; <email>cecuevas@uaeh.edu.mx</email> | |
| 700 | 1 | |a Adriana Fernandes da Silva |u Graduate Program in Dentistry, School of Dentistry, Federal University of Pelotas (UFPEL), Pelotas 96015-560, Brazil; <email>felipe.immich@ufpel.edu.br</email> (F.I.); <email>juliana.r.andrade@ufsc.br</email> (J.S.R.d.A.); <email>andressa.barboza@posgrad.ufsc.br</email> (A.d.S.B.); <email>adriana@ufpel.edu.br</email> (A.F.d.S.); <email>wellingtonl.fo@ufpel.edu.br</email> (W.L.d.O.d.R.); <email>piva@ufpel.edu.br</email> (E.P.) | |
| 700 | 1 | |a Wellington Luiz de Oliveira da Rosa |u Graduate Program in Dentistry, School of Dentistry, Federal University of Pelotas (UFPEL), Pelotas 96015-560, Brazil; <email>felipe.immich@ufpel.edu.br</email> (F.I.); <email>juliana.r.andrade@ufsc.br</email> (J.S.R.d.A.); <email>andressa.barboza@posgrad.ufsc.br</email> (A.d.S.B.); <email>adriana@ufpel.edu.br</email> (A.F.d.S.); <email>wellingtonl.fo@ufpel.edu.br</email> (W.L.d.O.d.R.); <email>piva@ufpel.edu.br</email> (E.P.) | |
| 700 | 1 | |a Borges, Álvaro Henrique |u Graduate Program in Dentistry, School of Dentistry, University of Cuiabá (UNIC), Cuiabá 78000-000, Brazil; <email>durvalinooliveira@gmail.com</email> (D.d.O.); <email>alvarohborges@gmail.com</email> (Á.H.B.) | |
| 700 | 1 | |a Neftali Lenin Villarreal Carreno |u Graduate Program in Materials Science and Engineering, Technological Development Center, Federal University of Pelotas (UFPEL), Pelotas 96010-610, Brazil; <email>neftali@ufpel.edu.br</email> | |
| 700 | 1 | |a Piva, Evandro |u Graduate Program in Dentistry, School of Dentistry, Federal University of Pelotas (UFPEL), Pelotas 96015-560, Brazil; <email>felipe.immich@ufpel.edu.br</email> (F.I.); <email>juliana.r.andrade@ufsc.br</email> (J.S.R.d.A.); <email>andressa.barboza@posgrad.ufsc.br</email> (A.d.S.B.); <email>adriana@ufpel.edu.br</email> (A.F.d.S.); <email>wellingtonl.fo@ufpel.edu.br</email> (W.L.d.O.d.R.); <email>piva@ufpel.edu.br</email> (E.P.); Graduate Program in Materials Science and Engineering, Technological Development Center, Federal University of Pelotas (UFPEL), Pelotas 96010-610, Brazil; <email>neftali@ufpel.edu.br</email> | |
| 700 | 1 | |a Rafael Guerra Lund |u Graduate Program in Dentistry, School of Dentistry, Federal University of Pelotas (UFPEL), Pelotas 96015-560, Brazil; <email>felipe.immich@ufpel.edu.br</email> (F.I.); <email>juliana.r.andrade@ufsc.br</email> (J.S.R.d.A.); <email>andressa.barboza@posgrad.ufsc.br</email> (A.d.S.B.); <email>adriana@ufpel.edu.br</email> (A.F.d.S.); <email>wellingtonl.fo@ufpel.edu.br</email> (W.L.d.O.d.R.); <email>piva@ufpel.edu.br</email> (E.P.); Graduate Program in Materials Science and Engineering, Technological Development Center, Federal University of Pelotas (UFPEL), Pelotas 96010-610, Brazil; <email>neftali@ufpel.edu.br</email> | |
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