How the intrinsic functional connectivity patterns of the semantic network support semantic processing

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I publikationen:Brain Imaging and Behavior vol. 18, no. 3 (Jun 2024), p. 539
Huvudupphov: Huang, Chengmei
Övriga upphov: Li, Aqian, Pang, Yingdan, Yang, Jiayi, Zhang, Jingxian, Wu, Xiaoyan, Mei, Leilei
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Springer Nature B.V.
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024 7 |a 10.1007/s11682-024-00849-y  |2 doi 
035 |a 3075469421 
045 2 |b d20240601  |b d20240630 
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100 1 |a Huang, Chengmei  |u Ministry of Education, Philosophy and Social Science Laboratory of Reading and Development in Children and Adolescents (South China Normal University), Guangzhou, China (GRID:grid.454828.7) (ISNI:0000 0004 0638 8050); South China Normal University, School of Psychology, Guangzhou, China (GRID:grid.263785.d) (ISNI:0000 0004 0368 7397); South China Normal University, Center for Studies of Psychological Application, Guangzhou, China (GRID:grid.263785.d) (ISNI:0000 0004 0368 7397) 
245 1 |a How the intrinsic functional connectivity patterns of the semantic network support semantic processing 
260 |b Springer Nature B.V.  |c Jun 2024 
513 |a Journal Article 
520 3 |a Semantic processing, a core of language comprehension, involves the activation of brain regions dispersed extensively across the frontal, temporal, and parietal cortices that compose the semantic network. To comprehend the functional structure of this semantic network and how it prepares for semantic processing, we investigated its intrinsic functional connectivity (FC) and the relation between this pattern and semantic processing ability in a large sample from the Human Connectome Project (HCP) dataset. We first defined a well-studied brain network for semantic processing, and then we characterized the within-network connectivity (WNC) and the between-network connectivity (BNC) within this network using a voxel-based global brain connectivity (GBC) method based on resting-state functional magnetic resonance imaging (fMRI). The results showed that 97.73% of the voxels in the semantic network displayed considerably greater WNC than BNC, demonstrating that the semantic network is a fairly encapsulated network. Moreover, multiple connector hubs in the semantic network were identified after applying the criterion of WNC > 1 SD above the mean WNC of the semantic network. More importantly, three of these connector hubs (i.e., the left anterior temporal lobe, angular gyrus, and orbital part of the inferior frontal gyrus) were reliably associated with semantic processing ability. Our findings suggest that the three identified regions use WNC as the central mechanism for supporting semantic processing and that task-independent spontaneous connectivity in the semantic network is essential for semantic processing. 
653 |a Hubs 
653 |a Semantics 
653 |a Magnetic resonance imaging 
653 |a Functional magnetic resonance imaging 
653 |a Temporal lobe 
653 |a Brain mapping 
653 |a Brain 
653 |a Frontal gyrus 
653 |a Cortex (frontal) 
653 |a Information processing 
653 |a Neuroimaging 
653 |a Neural networks 
700 1 |a Li, Aqian  |u Ministry of Education, Philosophy and Social Science Laboratory of Reading and Development in Children and Adolescents (South China Normal University), Guangzhou, China (GRID:grid.454828.7) (ISNI:0000 0004 0638 8050); South China Normal University, School of Psychology, Guangzhou, China (GRID:grid.263785.d) (ISNI:0000 0004 0368 7397); South China Normal University, Center for Studies of Psychological Application, Guangzhou, China (GRID:grid.263785.d) (ISNI:0000 0004 0368 7397) 
700 1 |a Pang, Yingdan  |u Ministry of Education, Philosophy and Social Science Laboratory of Reading and Development in Children and Adolescents (South China Normal University), Guangzhou, China (GRID:grid.454828.7) (ISNI:0000 0004 0638 8050); South China Normal University, School of Psychology, Guangzhou, China (GRID:grid.263785.d) (ISNI:0000 0004 0368 7397); South China Normal University, Center for Studies of Psychological Application, Guangzhou, China (GRID:grid.263785.d) (ISNI:0000 0004 0368 7397) 
700 1 |a Yang, Jiayi  |u Ministry of Education, Philosophy and Social Science Laboratory of Reading and Development in Children and Adolescents (South China Normal University), Guangzhou, China (GRID:grid.454828.7) (ISNI:0000 0004 0638 8050); South China Normal University, School of Psychology, Guangzhou, China (GRID:grid.263785.d) (ISNI:0000 0004 0368 7397); South China Normal University, Center for Studies of Psychological Application, Guangzhou, China (GRID:grid.263785.d) (ISNI:0000 0004 0368 7397) 
700 1 |a Zhang, Jingxian  |u Ministry of Education, Philosophy and Social Science Laboratory of Reading and Development in Children and Adolescents (South China Normal University), Guangzhou, China (GRID:grid.454828.7) (ISNI:0000 0004 0638 8050); South China Normal University, School of Psychology, Guangzhou, China (GRID:grid.263785.d) (ISNI:0000 0004 0368 7397); South China Normal University, Center for Studies of Psychological Application, Guangzhou, China (GRID:grid.263785.d) (ISNI:0000 0004 0368 7397) 
700 1 |a Wu, Xiaoyan  |u Ministry of Education, Philosophy and Social Science Laboratory of Reading and Development in Children and Adolescents (South China Normal University), Guangzhou, China (GRID:grid.454828.7) (ISNI:0000 0004 0638 8050); South China Normal University, School of Psychology, Guangzhou, China (GRID:grid.263785.d) (ISNI:0000 0004 0368 7397); South China Normal University, Center for Studies of Psychological Application, Guangzhou, China (GRID:grid.263785.d) (ISNI:0000 0004 0368 7397) 
700 1 |a Mei, Leilei  |u Ministry of Education, Philosophy and Social Science Laboratory of Reading and Development in Children and Adolescents (South China Normal University), Guangzhou, China (GRID:grid.454828.7) (ISNI:0000 0004 0638 8050) 
773 0 |t Brain Imaging and Behavior  |g vol. 18, no. 3 (Jun 2024), p. 539 
786 0 |d ProQuest  |t Health & Medical Collection 
856 4 1 |3 Citation/Abstract  |u https://www.proquest.com/docview/3075469421/abstract/embedded/H09TXR3UUZB2ISDL?source=fedsrch 
856 4 0 |3 Full Text - PDF  |u https://www.proquest.com/docview/3075469421/fulltextPDF/embedded/H09TXR3UUZB2ISDL?source=fedsrch