Respiratory syncytial virus (RSV) prevention: Perception and willingness of expectant parents in the Netherlands

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Publicado en:Vaccine vol. 44 (Jan 12, 2025)
Autor principal: Harteveld, Lisette M
Otros Autores: van Leeuwen, Lisanne M, Euser, Sjoerd M, Smit, Lucy J, Vollebregt, Karlijn C, Bogaert, Debby, van Houten, Marlies A
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Elsevier Limited
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Acceso en línea:Citation/Abstract
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001 3145638209
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022 |a 0264-410X 
022 |a 1873-2518 
024 7 |a 10.1016/j.vaccine.2024.126541  |2 doi 
035 |a 3145638209 
045 0 |b d20250112 
084 |a 109921  |2 nlm 
100 1 |a Harteveld, Lisette M 
245 1 |a Respiratory syncytial virus (RSV) prevention: Perception and willingness of expectant parents in the Netherlands 
260 |b Elsevier Limited  |c Jan 12, 2025 
513 |a Journal Article 
520 3 |a BackgroundRespiratory syncytial virus (RSV) is a leading cause of infant respiratory disease. Recent approval of preventive measures like a long-acting monoclonal antibody and a maternal vaccine signals a potential shift in early-life RSV infection control. However, success hinges on acceptance.MethodsWe conducted a cross-sectional survey among pregnant women and partners in the Netherlands, recruited via healthcare professionals, social media platforms, and the 9-Months Fair. The survey assessed willingness and motivation for maternal RSV vaccination and neonatal RSV immunization, including strategy preferences and informational needs.ResultsIn total 1001 pregnant women (mean age: 31.1 years) and their partners (mean age: 33.2 years) completed the survey. On average, they were 24 weeks pregnant at the time, and 54.6 % had no other children yet. The majority was Dutch-born (95.2 % of women); with 68.3 % of women having completed higher education and with overall strong pro-vaccination attitudes (93.9 % of partners intended to vaccinate their expected newborn). The overall acceptability to vaccination and immunization was high, with 87 % of respondents indicating they would (likely) accept both strategies. A positive attitude towards both methods was associated with previous experience with severity of RSV, intention to vaccinate the newborn and parental vaccination status during childhood and current pregnancy. When the choice was given, the majority of participants, in particular those with children and the intention to breastfeed, favoured maternal vaccination over passive immunization of infants (75.3 % of the pregnant and 71.6 % of the partners). A majority of the respondents cited optimal protection for the child and knowledge of RSV as important factors for accepting RSV prophylaxis.ConclusionsWhile most participants would accept both strategies for RSV protection of their infant, a majority, especially those with other children, favoured maternal vaccination, due to concerns about infant safety and awareness of RSV severity. 
651 4 |a Netherlands 
653 |a Infections 
653 |a Parents & parenting 
653 |a Respiratory syncytial virus 
653 |a Neonates 
653 |a Womens health 
653 |a COVID-19 vaccines 
653 |a Pregnancy 
653 |a Vaccines 
653 |a Regression analysis 
653 |a Immunization (passive) 
653 |a Infants 
653 |a Disease control 
653 |a Monoclonal antibodies 
653 |a Social networks 
653 |a Questionnaires 
653 |a Influenza 
653 |a Health care expenditures 
653 |a Age 
653 |a Disease prevention 
653 |a Global health 
653 |a Children 
653 |a Immunization 
653 |a Respiratory diseases 
653 |a Prevention programs 
653 |a Attitudes 
653 |a Education 
653 |a Medical research 
653 |a Surveys 
653 |a Whooping cough 
653 |a Newborn babies 
653 |a Social 
700 1 |a van Leeuwen, Lisanne M 
700 1 |a Euser, Sjoerd M 
700 1 |a Smit, Lucy J 
700 1 |a Vollebregt, Karlijn C 
700 1 |a Bogaert, Debby 
700 1 |a van Houten, Marlies A 
773 0 |t Vaccine  |g vol. 44 (Jan 12, 2025) 
786 0 |d ProQuest  |t Healthcare Administration Database 
856 4 1 |3 Citation/Abstract  |u https://www.proquest.com/docview/3145638209/abstract/embedded/7BTGNMKEMPT1V9Z2?source=fedsrch 
856 4 0 |3 Full Text  |u https://www.proquest.com/docview/3145638209/fulltext/embedded/7BTGNMKEMPT1V9Z2?source=fedsrch 
856 4 0 |3 Full Text - PDF  |u https://www.proquest.com/docview/3145638209/fulltextPDF/embedded/7BTGNMKEMPT1V9Z2?source=fedsrch