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NF–κB mediates transactivation of HNRNPD, resulting in PTEN destabilization and constitutive activation of the PI3K–AKT pathway in oral cancer cells

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Pubblicato in:bioRxiv (Jan 5, 2025)
Autore principale: Kumar, Vikas
Altri autori: Mittal, Anjani, Kumar, Anurag, Moien Rasheed Lone, Yadav, Vandana, Verma, Priya, Pradhan, Dibyabhaba, Mishra, Deepika, Thakar, Alok, Chauhan, Shaym S
Pubblicazione:
Cold Spring Harbor Laboratory Press
Soggetti:
Transcriptomes
PTEN protein
3' Untranslated regions
Autophagy
Oral cancer
TOR protein
Oral squamous cell carcinoma
RNA-binding protein
Therapeutic targets
Cell proliferation
Oral carcinoma
1-Phosphatidylinositol 3-kinase
Cell migration
AKT protein
Senescence
Cell survival
Cell activation
Accesso online:Citation/Abstract
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