A paradigm to study the learning of muscle activity patterns outside of the natural repertoire

Guardat en:
Dades bibliogràfiques
Publicat a:bioRxiv (Feb 14, 2025)
Autor principal: Ghavampour, Ali
Altres autors: Emanuele, Marco, Shuja Riyaz Sayyid, Jean-Jacques Orban De Xivry, Michaels, Jonathan A, Pruszynski, J Andrew, Diedrichsen, Joern
Publicat:
Cold Spring Harbor Laboratory Press
Matèries:
Accés en línia:Citation/Abstract
Full Text - PDF
Full text outside of ProQuest
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

MARC

LEADER 00000nab a2200000uu 4500
001 3166844361
003 UK-CbPIL
022 |a 2692-8205 
024 7 |a 10.1101/2025.02.13.638098  |2 doi 
035 |a 3166844361 
045 0 |b d20250214 
100 1 |a Ghavampour, Ali 
245 1 |a A paradigm to study the learning of muscle activity patterns outside of the natural repertoire 
260 |b Cold Spring Harbor Laboratory Press  |c Feb 14, 2025 
513 |a Working Paper 
520 3 |a The acquisition of novel muscle activity patterns is a key aspect of motor skill learning which can be seen at play, for example, when beginner musicians learn new guitar or piano chords. To study this process, here we introduce a new paradigm that requires quick and synchronous flexion and extension of multiple fingers. First, participants practiced all the 242 possible combinations of isometric finger flexion and extension around the metacarpophalangeal joint (i.e., chords). We found that some chords were initially extremely challenging, but participants could eventually achieve them with practice, showing that the initial difficulty did not reflect hard biomechanical constraints imposed by the interaction of tendons and ligaments. In a second experiment we found that chord learning was largely chord-specific and did not generalize to untrained chords. Finally, we explored which factors make some chords more difficult than others. Difficulty was well predicted by the muscle activity pattern required by that chord. Interestingly, difficulty related to how similar chords' muscle activity patterns are to the muscle activity patterns required by everyday hand use, and to the overall size of the muscle activity. Together, our results suggest that the new paradigm introduced in this work may provide a valuable tool to study the neural processes underlying the acquisition of novel muscle activity patterns in the human motor system.Competing Interest StatementThe authors have declared no competing interest. 
653 |a Motor skill 
653 |a Muscle contraction 
653 |a Motor skill learning 
653 |a Muscle function 
653 |a Tendons 
653 |a Activity patterns 
700 1 |a Emanuele, Marco 
700 1 |a Shuja Riyaz Sayyid 
700 1 |a Jean-Jacques Orban De Xivry 
700 1 |a Michaels, Jonathan A 
700 1 |a Pruszynski, J Andrew 
700 1 |a Diedrichsen, Joern 
773 0 |t bioRxiv  |g (Feb 14, 2025) 
786 0 |d ProQuest  |t Biological Science Database 
856 4 1 |3 Citation/Abstract  |u https://www.proquest.com/docview/3166844361/abstract/embedded/L8HZQI7Z43R0LA5T?source=fedsrch 
856 4 0 |3 Full Text - PDF  |u https://www.proquest.com/docview/3166844361/fulltextPDF/embedded/L8HZQI7Z43R0LA5T?source=fedsrch 
856 4 0 |3 Full text outside of ProQuest  |u https://www.biorxiv.org/content/10.1101/2025.02.13.638098v1