Buchumschlag

Neural and Behavioral Adaptation to Listening with a Unilateral Cochlear Implant (CI)

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Veröffentlicht in:bioRxiv (Feb 18, 2025)
1. Verfasser: Woestmann, Malte
Weitere Verfasser: Meineke, Hannah Marie, Schoenweiler, Rainer, Hollfelder, Daniela, Karl-Ludwig Bruchhage, Leichtle, Anke, Obleser, Jonas
Veröffentlicht:
Cold Spring Harbor Laboratory Press
Schlagworte:
Oscillations
Speech perception
EEG
Cochlear implants
Hearing loss
Auditory perception
Listening
Temporal variations
Information processing
Auditory plasticity
Frequency dependence
Ear
Attention
Auditory system
Cochlea
Neural coding
Deafness
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Abstract:The human auditory system must encode sounds and separate relevant input from noise. Hearing loss hurts both processes, but profound hearing loss and deafness can be treated with a Cochlear Implant (CI). Here, we probe the human brains adaptation to electrical hearing with a CI in unilaterally implanted CI users with normal or aided contralateral hearing, in the first and seventh month after CI activation. In addition to clinical measures of speech comprehension, electroencephalography (EEG) recordings during passive listening to amplitude-modulated (AM) sounds and an active spatial listening task with competing talkers were analyzed. We demonstrate that, first, adaptation to hearing with a CI is accompanied by decreasing cortical overrepresentation and increasing auditory temporal coding fidelity: After six month of CI use, auditory phase-locking during passive listening relatively decreased for 4-Hz AM sounds but increased for 40-Hz AM sounds. Second, strongest benefits of listening with the CI (i.e., CI on vs. off) in the spatial-listening task occurred when the CI ear was primarily exposed to target sound. Here, the power of lateralized alpha oscillations (~10 Hz) served as a robust signature of spatial attention, independent of time (1st vs 7th month) and listening modality (with vs. without CI). Stronger lateralized alpha modulation in the hemisphere contralateral to the non-implanted ear suggests asymmetrical allocation of auditory spatial attention, operating preferentially on the input to the non-implanted ear. These findings highlight CI-related plasticity in auditory perception and a persistent attentional bias toward the non-implanted ear, emphasizing the need to consider bilateral auditory input in CI rehabilitation.Competing Interest StatementThe authors have declared no competing interest.
ISSN:2692-8205
DOI:10.1101/2025.02.17.638598
Quelle:Biological Science Database