EEG responses to auditory cues predict fluency variability and stuttering intervention outcome

Збережено в:
Бібліографічні деталі
Опубліковано в::bioRxiv (Feb 24, 2025)
Автор: Rocha, Monica Filipa
Інші автори: Carmona, Jaqueline, Joao Mendonca Correia
Опубліковано:
Cold Spring Harbor Laboratory Press
Предмети:
Онлайн доступ:Citation/Abstract
Full text outside of ProQuest
Теги: Додати тег
Немає тегів, Будьте першим, хто поставить тег для цього запису!

MARC

LEADER 00000nab a2200000uu 4500
001 3170650130
003 UK-CbPIL
022 |a 2692-8205 
024 7 |a 10.1101/2025.02.21.635719  |2 doi 
035 |a 3170650130 
045 0 |b d20250224 
100 1 |a Rocha, Monica Filipa 
245 1 |a EEG responses to auditory cues predict fluency variability and stuttering intervention outcome 
260 |b Cold Spring Harbor Laboratory Press  |c Feb 24, 2025 
513 |a Working Paper 
520 3 |a Stuttering is a variable speech disorder whose brain mechanisms remain unknown. Sensorimotor brain circuits, critical for motor-speech control, including auditory processing necessary for speech prediction and monitoring, have been linked to the disorder. Despite considerable advances, it remains unclear whether auditory circuits relate to stuttering variability, and whether the panoply of interventions for persons who stutter can lead to brain changes within these circuits. We employed electroencephalography (EEG), in a group of persons who stutter, in combination with auditory probes to tap onto the importance of auditory cortical regions in stuttering variability. Participants produced flexible speech (i.e., describing visual scenes) and non-flexible speech (i.e., reading syllables), following an auditory cue. More pronounced P200 auditory evoked potentials were observed in participants with higher dysfluency rates, mainly in the spontaneous speech task. Interestingly, speech therapy intervention led to a reduction of the P200 potential, which was in turn significantly related to fluency improvements. Furthermore, EEG response patterns discriminative of cue frequency (400 or 800 Hz tones) were also predictive of dysfluency scores. Our study highlights the involvement of auditory cortical processing and that of auditory attention in stuttering variability. We support that a higher state of auditory alertness may be implicated in the sensorimotor mechanisms of stuttering, and that speech therapy interventions promoting more self-confident communication can restraint auditory alertness, and potentially reduce speech dysfluencies.Competing Interest StatementThe authors have declared no competing interest. 
653 |a Speech 
653 |a Hearing 
653 |a Visual pathways 
653 |a Information processing 
653 |a Speech therapy 
653 |a Sensorimotor system 
653 |a Electroencephalography 
653 |a Auditory pathways 
653 |a EEG 
653 |a Motor task performance 
653 |a Stuttering 
653 |a Auditory evoked potentials 
653 |a Circuits 
700 1 |a Carmona, Jaqueline 
700 1 |a Joao Mendonca Correia 
773 0 |t bioRxiv  |g (Feb 24, 2025) 
786 0 |d ProQuest  |t Biological Science Database 
856 4 1 |3 Citation/Abstract  |u https://www.proquest.com/docview/3170650130/abstract/embedded/L8HZQI7Z43R0LA5T?source=fedsrch 
856 4 0 |3 Full text outside of ProQuest  |u https://www.biorxiv.org/content/10.1101/2025.02.21.635719v1