Status on Genetic Resistance to Rice Blast Disease in the Post-Genomic Era

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Publicado en:Plants vol. 14, no. 5 (2025), p. 807
Autor principal: Pedrozo, Rodrigo
Otros Autores: Osakina, Aron, Huang, Yixiao, Nicolli, Camila Primieri, Wang, Li, Jia, Yulin
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MDPI AG
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100 1 |a Pedrozo, Rodrigo  |u USDA ARS Dale Bumpers National Rice Research Center, Stuttgart, AR 72160, USA; <email>rodrigo.pedrozo@usda.gov</email> (R.P.); <email>aron.osakina@usda.gov</email> (A.O.); <email>yixiao.huang@usda.gov</email> (Y.H.); <email>li.wang@usda.gov</email> (L.W.) 
245 1 |a Status on Genetic Resistance to Rice Blast Disease in the Post-Genomic Era 
260 |b MDPI AG  |c 2025 
513 |a Journal Article 
520 3 |a Rice blast, caused by Magnaporthe oryzae, is a major threat to global rice production, necessitating the development of resistant cultivars through genetic improvement. Breakthroughs in rice genomics, including the complete genome sequencing of japonica and indica subspecies and the availability of various sequence-based molecular markers, have greatly advanced the genetic analysis of blast resistance. To date, approximately 122 blast-resistance genes have been identified, with 39 of these genes cloned and molecularly characterized. The application of these findings in marker-assisted selection (MAS) has significantly improved rice breeding, allowing for the efficient integration of multiple resistance genes into elite cultivars, enhancing both the durability and spectrum of resistance. Pangenomic studies, along with AI-driven tools like AlphaFold2, RoseTTAFold, and AlphaFold3, have further accelerated the identification and functional characterization of resistance genes, expediting the breeding process. Future rice blast disease management will depend on leveraging these advanced genomic and computational technologies. Emphasis should be placed on enhancing computational tools for the large-scale screening of resistance genes and utilizing gene editing technologies such as CRISPR-Cas9 for functional validation and targeted resistance enhancement and deployment. These approaches will be crucial for advancing rice blast resistance, ensuring food security, and promoting agricultural sustainability. 
651 4 |a China 
653 |a Infections 
653 |a Fungi 
653 |a Marker-assisted selection 
653 |a Pathogens 
653 |a Disease resistance 
653 |a Humidity 
653 |a Genetic analysis 
653 |a Plant breeding 
653 |a Genetic modification 
653 |a Genomics 
653 |a CRISPR 
653 |a Genes 
653 |a Disease 
653 |a Biology 
653 |a Computer applications 
653 |a Cultivars 
653 |a Rice blast 
653 |a Food security 
653 |a Crop production 
653 |a Genetic improvement 
653 |a Gene sequencing 
653 |a Genome editing 
653 |a Cloning 
653 |a Epidemics 
653 |a Chromosomes 
653 |a Sustainable agriculture 
653 |a Software 
653 |a Climate change 
653 |a Enzymes 
700 1 |a Osakina, Aron  |u USDA ARS Dale Bumpers National Rice Research Center, Stuttgart, AR 72160, USA; <email>rodrigo.pedrozo@usda.gov</email> (R.P.); <email>aron.osakina@usda.gov</email> (A.O.); <email>yixiao.huang@usda.gov</email> (Y.H.); <email>li.wang@usda.gov</email> (L.W.); Department of Biology, Washington University in St. Louis, St. Louis, MO 63130, USA 
700 1 |a Huang, Yixiao  |u USDA ARS Dale Bumpers National Rice Research Center, Stuttgart, AR 72160, USA; <email>rodrigo.pedrozo@usda.gov</email> (R.P.); <email>aron.osakina@usda.gov</email> (A.O.); <email>yixiao.huang@usda.gov</email> (Y.H.); <email>li.wang@usda.gov</email> (L.W.) 
700 1 |a Nicolli, Camila Primieri  |u Entomology and Plant Pathology Department, University of Arkansas, Rice Research and Extension Center (RREC), Stuttgart, AR 72160, USA; <email>cnicolli@uada.edu</email> 
700 1 |a Wang, Li  |u USDA ARS Dale Bumpers National Rice Research Center, Stuttgart, AR 72160, USA; <email>rodrigo.pedrozo@usda.gov</email> (R.P.); <email>aron.osakina@usda.gov</email> (A.O.); <email>yixiao.huang@usda.gov</email> (Y.H.); <email>li.wang@usda.gov</email> (L.W.) 
700 1 |a Jia, Yulin  |u USDA ARS Dale Bumpers National Rice Research Center, Stuttgart, AR 72160, USA; <email>rodrigo.pedrozo@usda.gov</email> (R.P.); <email>aron.osakina@usda.gov</email> (A.O.); <email>yixiao.huang@usda.gov</email> (Y.H.); <email>li.wang@usda.gov</email> (L.W.) 
773 0 |t Plants  |g vol. 14, no. 5 (2025), p. 807 
786 0 |d ProQuest  |t Agriculture Science Database 
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