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BMAL1 attenuates intervertebral disc degeneration by activating the SIRT1/PGC-1α pathway: evidence from vitro studies

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Pubblicato in:Scientific Reports (Nature Publisher Group) vol. 15, no. 1 (2025), p. 9651
Pubblicazione:
Nature Publishing Group
Soggetti:
SIRT1 protein
Reactive oxygen species
Mitophagy
Neurodegeneration
PTEN-induced putative kinase
Apoptosis
Nucleus pulposus
Senescence
Intervertebral discs
BMAL1 protein
siRNA
Inflammation
Biosynthesis
Metabolism
Protein expression
Oxidative stress
Proteins
Degenerative disc disease
Back pain
Aging
Hospitals
Cell growth
Enzymes
Environmental
Accesso online:Citation/Abstract
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