Long-Term Results of Segmentectomy vs. Lobectomy for c-Stage IA Lung Cancer: A Real-Life Study with a Propensity Score Analysis Based on a National Cohort
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| Publicat a: | Journal of Clinical Medicine vol. 14, no. 7 (2025), p. 2267 |
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| Autor principal: | |
| Altres autors: | , , , , , , , , |
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MDPI AG
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| Accés en línia: | Citation/Abstract Full Text + Graphics Full Text - PDF |
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| 001 | 3188798035 | ||
| 003 | UK-CbPIL | ||
| 022 | |a 2077-0383 | ||
| 024 | 7 | |a 10.3390/jcm14072267 |2 doi | |
| 035 | |a 3188798035 | ||
| 045 | 2 | |b d20250101 |b d20251231 | |
| 100 | 1 | |a Lopez, Iker |u Department of Thoracic Surgery, Donostia University Hospital, 20014 San Sebastián-Donostia, Spain; <email>borja.aguinagaldevaliente@osakidetza.eus</email> (B.A.); <email>arantza.fernandez-mongeumaran@osakidetza.eus</email> (A.F.-M.); <email>jonander.lizarbebon@osakidetza.eus</email> (J.A.L.); Lung and Pleural Diseases Research Group, Biogipuzkoa Health Research Institute, 20014 San Sebastián-Donostia, Spain | |
| 245 | 1 | |a Long-Term Results of Segmentectomy vs. Lobectomy for c-Stage IA Lung Cancer: A Real-Life Study with a Propensity Score Analysis Based on a National Cohort | |
| 260 | |b MDPI AG |c 2025 | ||
| 513 | |a Journal Article | ||
| 520 | 3 | |a Background/Objectives: The objective was to compare the results of segmentectomy and lobectomy in the treatment of c-stage IA lung cancer in terms of tumor recurrence and 5-year survival. Methods: An observational study was performed using 3533 patients included in the registry of the Spanish VATS Group (GEVATS) of the Spanish Society of Thoracic Surgery (SECT) between 2016 and 2018. A total of 1004 lobectomies and 83 segmentectomies in c-stage IA were selected. Two comparable groups were selected through 2:1 propensity score matching with patient-, tumor- and surgery-related variables, leaving 166 lobectomies and 83 segmentectomies. Tumor recurrence was analyzed by Fisher’s test and overall, cancer-specific, recurrence-free and disease-free survival by Kaplan-Meier and Log-rank tests. Results: Overall recurrence was 23.7% in both groups, with a predominance of locoregional recurrence in segmentectomy (16.2% vs. 11.2%) and distant recurrence in lobectomy (12.5% vs. 7.5%). There was no difference between the two groups in any of the survival types. Overall survival at 5 years was 73.5% (95% CI: 65.5–82.4%) in the lobectomy group vs. 73.1% (95% CI: 60.1–88.9%) in the segmentectomy group. Conclusions: Anatomic segmentectomy may be a valid option in the treatment of c-stage IA lung cancer since the recurrence and long-term survival outcomes compared to lobectomy are equivalent. | |
| 653 | |a Clinical trials | ||
| 653 | |a Observational studies | ||
| 653 | |a Lung cancer | ||
| 653 | |a Ethics | ||
| 653 | |a Tumors | ||
| 653 | |a Thoracic surgery | ||
| 653 | |a Epidemiology | ||
| 653 | |a Values | ||
| 653 | |a Survival analysis | ||
| 653 | |a Lymphatic system | ||
| 700 | 1 | |a Aguinagalde, Borja |u Department of Thoracic Surgery, Donostia University Hospital, 20014 San Sebastián-Donostia, Spain; <email>borja.aguinagaldevaliente@osakidetza.eus</email> (B.A.); <email>arantza.fernandez-mongeumaran@osakidetza.eus</email> (A.F.-M.); <email>jonander.lizarbebon@osakidetza.eus</email> (J.A.L.); Lung and Pleural Diseases Research Group, Biogipuzkoa Health Research Institute, 20014 San Sebastián-Donostia, Spain | |
| 700 | 1 | |a Ferrer-Bonsoms, Juan A |u Department of Biomedical Engineering and Science, School of Engineering (TECNUN), University of Navarra, 20018 San Sebastián-Donostia, Spain; <email>jafhernandez@unav.es</email> | |
| 700 | 1 | |a Sánchez, Laura |u Department of Thoracic Surgery, Marqués de Valdecilla University Hospital, 39008 Santander, Spain; <email>lasanchez@humv.es</email> | |
| 700 | 1 | |a Ascanio, Fernando |u Department of Thoracic Surgery, Vall d’Hebron University Hospital, 08035 Barcelona, Spain; <email>fernando.ascanio@vallhebron.cat</email> | |
| 700 | 1 | |a Sesma, Julio |u Department of Thoracic Surgery, General de Alicante University Hospital, 03550 Alicante, Spain; <email>jsesmaromero@gmail.com</email> | |
| 700 | 1 | |a Recuero, José Luis |u Thoracic Surgery Department, Miguel Servet University Hospital, IIS Aragón, 50009 Zaragoza, Spain; <email>jlrecuero@salud.aragon.es</email> (J.L.R.); <email>raulembun@gmail.com</email> (R.E.) | |
| 700 | 1 | |a Fernandez-Monge, Arantza |u Department of Thoracic Surgery, Donostia University Hospital, 20014 San Sebastián-Donostia, Spain; <email>borja.aguinagaldevaliente@osakidetza.eus</email> (B.A.); <email>arantza.fernandez-mongeumaran@osakidetza.eus</email> (A.F.-M.); <email>jonander.lizarbebon@osakidetza.eus</email> (J.A.L.); Lung and Pleural Diseases Research Group, Biogipuzkoa Health Research Institute, 20014 San Sebastián-Donostia, Spain | |
| 700 | 1 | |a Lizarbe, Jon A |u Department of Thoracic Surgery, Donostia University Hospital, 20014 San Sebastián-Donostia, Spain; <email>borja.aguinagaldevaliente@osakidetza.eus</email> (B.A.); <email>arantza.fernandez-mongeumaran@osakidetza.eus</email> (A.F.-M.); <email>jonander.lizarbebon@osakidetza.eus</email> (J.A.L.); Lung and Pleural Diseases Research Group, Biogipuzkoa Health Research Institute, 20014 San Sebastián-Donostia, Spain | |
| 700 | 1 | |a Embun, Raul |u Thoracic Surgery Department, Miguel Servet University Hospital, IIS Aragón, 50009 Zaragoza, Spain; <email>jlrecuero@salud.aragon.es</email> (J.L.R.); <email>raulembun@gmail.com</email> (R.E.) | |
| 773 | 0 | |t Journal of Clinical Medicine |g vol. 14, no. 7 (2025), p. 2267 | |
| 786 | 0 | |d ProQuest |t Health & Medical Collection | |
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