Functional divisions of the left anterior and posterior temporoparietal junction for phonological and semantic processing in Chinese character reading

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Pubblicato in:NeuroImage vol. 311 (May 1, 2025)
Autore principale: Li, Aqian
Altri autori: Chen, Chuansheng, Feng, Yuan, Hu, Rui, Feng, Xiaoxue, Yang, Jingyu, Lin, Xingying, Mei, Leilei
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Elsevier Limited
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022 |a 1053-8119 
022 |a 1095-9572 
024 7 |a 10.1016/j.neuroimage.2025.121201  |2 doi 
035 |a 3191577975 
045 0 |b d20250501 
084 |a 221628  |2 nlm 
100 1 |a Li, Aqian  |u Philosophy and Social Science Laboratory of Reading and Development in Children and Adolescents (South China Normal University), Ministry of Education, China 
245 1 |a Functional divisions of the left anterior and posterior temporoparietal junction for phonological and semantic processing in Chinese character reading 
260 |b Elsevier Limited  |c May 1, 2025 
513 |a Journal Article 
520 3 |a Previous studies have shown that the left temporoparietal junction (TPJ) plays a critical role in word reading. Nevertheless, there is still controversy surrounding the phonological and semantic functions of the left TPJ. The parietal unified connectivity-biased computation (PUCC) model posits that the function of the left TPJ depends on both the neurocomputation of this local area and its long-range connectivity. To clarify the specific roles of different TPJ subregions in phonological and semantic processing of Chinese characters, the present study used connectivity-based clustering to identify seven subdivisions within the left TPJ, and conducted comprehensive analyses including functional and structural connectivity, univariate and multivariate analyses (i.e., representational similarity analysis, RSA) on multimodal imaging data (task-state fMRI, resting-state fMRI, and diffusion-weighted imaging [DWI]). Functional and structural connectivity analyses revealed that the left anterior TPJ had stronger connections with the phonological network, while the left posterior TPJ had stronger connections with the semantic network. RSA revealed that the left anterior and posterior TPJ represented phonological and semantic information of Chinese characters, respectively. More importantly, the phonological and semantic representations of the left TPJ were respectively correlated with its functional connectivity to the phonological and semantic networks. Altogether, our results provide a more elaborate perspective on the functional dissociation of the left anterior and posterior TPJ in phonological and semantic processing of Chinese characters, and support the PUCC model. 
653 |a Neuroimaging 
653 |a Functional magnetic resonance imaging 
653 |a Phonological processing 
653 |a Brain research 
653 |a Semantic processing 
653 |a Information processing 
653 |a Automation 
653 |a Medical imaging 
653 |a Structure-function relationships 
653 |a Phonology 
653 |a Chinese languages 
653 |a Neural networks 
653 |a Semantics 
653 |a Characters 
653 |a Resting 
653 |a Information dissemination 
653 |a Networks 
653 |a Dissociation 
653 |a Functional connectivity 
653 |a Computation 
653 |a Semantic networks 
653 |a Clustering 
700 1 |a Chen, Chuansheng  |u Department of Psychological Science, University of California, Irvine, CA, USA 
700 1 |a Feng, Yuan  |u Philosophy and Social Science Laboratory of Reading and Development in Children and Adolescents (South China Normal University), Ministry of Education, China 
700 1 |a Hu, Rui  |u Philosophy and Social Science Laboratory of Reading and Development in Children and Adolescents (South China Normal University), Ministry of Education, China 
700 1 |a Feng, Xiaoxue  |u Philosophy and Social Science Laboratory of Reading and Development in Children and Adolescents (South China Normal University), Ministry of Education, China 
700 1 |a Yang, Jingyu  |u Philosophy and Social Science Laboratory of Reading and Development in Children and Adolescents (South China Normal University), Ministry of Education, China 
700 1 |a Lin, Xingying  |u Philosophy and Social Science Laboratory of Reading and Development in Children and Adolescents (South China Normal University), Ministry of Education, China 
700 1 |a Mei, Leilei  |u Philosophy and Social Science Laboratory of Reading and Development in Children and Adolescents (South China Normal University), Ministry of Education, China 
773 0 |t NeuroImage  |g vol. 311 (May 1, 2025) 
786 0 |d ProQuest  |t Health & Medical Collection 
856 4 1 |3 Citation/Abstract  |u https://www.proquest.com/docview/3191577975/abstract/embedded/L8HZQI7Z43R0LA5T?source=fedsrch 
856 4 0 |3 Full Text  |u https://www.proquest.com/docview/3191577975/fulltext/embedded/L8HZQI7Z43R0LA5T?source=fedsrch 
856 4 0 |3 Full Text - PDF  |u https://www.proquest.com/docview/3191577975/fulltextPDF/embedded/L8HZQI7Z43R0LA5T?source=fedsrch