Muscle Function, Muscle Disease, and Positron Emission Tomography-Computed Tomography: A Narrative Review
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| Publicat a: | Cureus vol. 17, no. 2 (2025) |
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Springer Nature B.V.
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| Accés en línia: | Citation/Abstract Full Text Full Text - PDF |
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| Resum: | 18F-fluorodeoxyglucose (18F-FDG) is a radiopharmaceutical that exhibits glucose-like kinetics and is used in positron emission tomography (PET). 18F-FDG is used for cancer diagnosis in clinical practice. However, 18F-FDG uptake is also observed in normal organs, such as the brain, liver, and heart, with high glucose consumption. Moreover, 18F-FDG uptake is also observed in muscles, where its accumulation and radioactivity reflect muscle activity. Dystonia is characterized by excessive muscle movement. Recently, 18F-FDG and technetium-99m-methoxyisobutyl isocyanide ([99mTc]MIBI) have been used for the diagnosis and botulinum toxin therapy evaluation of dystonia.This review aimed to summarize the utility of 18F-FDG-PET for the evaluation of muscle activity and diagnosis of muscle diseases such as dystonia, polymyositis, dermatomyositis, and polymyalgia rheumatica. |
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| ISSN: | 2168-8184 2154-4786 |
| DOI: | 10.7759/cureus.79857 |
| Font: | Health & Medical Collection |