The Risk of Developing Tinnitus and Air Pollution Exposure

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Pubblicato in:Atmosphere vol. 16, no. 5 (2025), p. 618
Autore principale: Po-Yu, Lai
Altri autori: Chang-Yin, Lee, Chang Kuang-Hsi, Yu-Kang, Chang, Yi-Chao, Hsu, Ing-Ming, Chiu, Tsai Stella Chin-Shaw, Der-Yang, Cho, Cheng-Li, Lin, Tsung-Hsing, Lin, Wu-Lung, Chuang
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MDPI AG
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001 3211859402
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022 |a 2073-4433 
024 7 |a 10.3390/atmos16050618  |2 doi 
035 |a 3211859402 
045 2 |b d20250101  |b d20251231 
084 |a 231428  |2 nlm 
100 1 |a Po-Yu, Lai  |u Department of Family Medicine, Tungs’ Taichung MetroHarbor Hospital, Taichung 435, Taiwan; b101092091@tmu.edu.tw 
245 1 |a The Risk of Developing Tinnitus and Air Pollution Exposure 
260 |b MDPI AG  |c 2025 
513 |a Journal Article 
520 3 |a (1) Background: The role of air pollutants as risk factors for tinnitus remains unclear. To address this gap in research, we conducted a nationwide retrospective cohort study in Taiwan by integrating patients’ clinical data with daily air quality data to evaluate the environmental risk factors associated with tinnitus. (2) Methods: The Taiwan National Health Research Database (NHIRD) includes medical records for nearly all residents of Taiwan. To assess pollution levels, we used daily air quality data from the Taiwan Environmental Protection Agency regarding SO2, CO, NO, NOX, and particulate matter (PM2.5 and PM10). We merged the NHIRD data with air quality information based on the residents’ locations and the positions of air quality monitoring stations. Pollutant levels were then categorized into quartiles (Q1, Q2, Q3, and Q4). (3) Results: This study included 284,318 subjects. After controlling for covariates, the adjusted HR (95 CI%) for tinnitus increased with increasing SO2, CO, NO, NOX, PM2.5, and PM10 exposure levels, specifically from 1.24 (95 CI% = 1.18, 1.30) to 1.35 (95 CI% = 1.28–1.41); from 1.15 (95 CI% = 1.09, 1.21) to 1.90 (95 CI% = 1.81, 2.00); from 0.86 (95 CI% = 0.82, 0.91) to 1.69 (95 CI% = 1.62, 1.77); from 1.62 (95 CI% = 1.54, 1.71) to 1.69 (95 CI% = 1.60, 1.77); from 0.16 (95 CI% = 0.15, 0.18) to 2.70 (95 CI% = 2.57, 2.84); and from 2.53 (95 CI% = 2.38, 2.69) to 3.58 (95 CI% = 3.39, 3.78), respectively, compared to the Q1 concentrations for all air pollutants. (4) Conclusions: During the 15-year follow-up period, we found a significant positive correlation between air pollutant exposure and the risk of tinnitus. 
651 4 |a Taiwan 
653 |a Air quality 
653 |a Alcohol abuse 
653 |a Air pollution 
653 |a Air monitoring 
653 |a Environmental protection 
653 |a Exposure 
653 |a Particulate matter 
653 |a Risk factors 
653 |a Public health 
653 |a Tinnitus 
653 |a Urbanization 
653 |a Pollution levels 
653 |a Pollutants 
653 |a Humidity 
653 |a Chronic illnesses 
653 |a Sulfur dioxide 
653 |a Environmental risk 
653 |a Outdoor air quality 
653 |a Chronic obstructive pulmonary disease 
653 |a Osteoporosis 
653 |a Particulate emissions 
653 |a Asthma 
653 |a Suspended particulate matter 
653 |a Medical records 
653 |a Nitrogen dioxide 
700 1 |a Chang-Yin, Lee  |u College of Medicine, The School of Chinese Medicine for Post Baccalaureate, I-Shou University (Yancho Campus), Kaohsiung 824, Taiwan; ed106638@isu.edu.tw 
700 1 |a Chang Kuang-Hsi  |u Department of Medical Research, Tungs’ Taichung MetroHarbor Hospital, Taichung 435, Taiwan; kuanghsichang@gmail.com (K.-H.C.); yogurt8306@gmail.com (Y.-K.C.) 
700 1 |a Yu-Kang, Chang  |u Department of Medical Research, Tungs’ Taichung MetroHarbor Hospital, Taichung 435, Taiwan; kuanghsichang@gmail.com (K.-H.C.); yogurt8306@gmail.com (Y.-K.C.) 
700 1 |a Yi-Chao, Hsu  |u Institute of Biomedical Sciences, Mackay Medical College, New Taipei City 252, Taiwan; hsuyc@mmc.edu.tw 
700 1 |a Ing-Ming, Chiu  |u <label>11</label>Institute of Biomedical Sciences, China Medical University, Taichung 402, Taiwan; ingming@gmail.com (I.-M.C.); 
700 1 |a Tsai Stella Chin-Shaw  |u <label>12</label>Department of Otolaryngology, Tungs’ Taichung MetroHarbor Hospital, Taichung 435, Taiwan; tsaistella111@gmail.com 
700 1 |a Der-Yang, Cho  |u <label>11</label>Institute of Biomedical Sciences, China Medical University, Taichung 402, Taiwan; ingming@gmail.com (I.-M.C.); 
700 1 |a Cheng-Li, Lin  |u <label>16</label>Management Office for Health Data, China Medical University Hospital, Taichung 404, Taiwan; orangechengli@gmail.com 
700 1 |a Tsung-Hsing, Lin  |u <label>18</label>Department of Emergency Medicine, Kuang Tien General Hospital, Taichung 433, Taiwan 
700 1 |a Wu-Lung, Chuang  |u <label>19</label>Division of Endocrinology and Metabolism, Department of Internal Medicine, Changhua Christian Hospital, Changhua 500, Taiwan 
773 0 |t Atmosphere  |g vol. 16, no. 5 (2025), p. 618 
786 0 |d ProQuest  |t Publicly Available Content Database 
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