Environmentally Friendly Extraction of Bioactive Compounds from Spruce and Pine Needles to Obtain Extracts with Antioxidant and Antimicrobial Activity

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Publicado en:Rigas Tehniskas Universitates Zinatniskie Raksti vol. 29, no. 1 (2025), p. 184-201
Autor Principal: Marcis, Mezulis
Outros autores: Arbidans Lauris, Nikolajeva Vizma, Maris, Lauberts, Grinfelds Uldis, Klavins Maris
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Riga Technical University
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022 |a 2255-8837 
024 7 |a 10.2478/rtuect-2025-0013  |2 doi 
035 |a 3216849232 
045 2 |b d20250101  |b d20251231 
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100 1 |a Marcis, Mezulis  |u 1,2,6 Department of Environmental Science , University of Latvia , Jelgavas st. 1 , Riga , LV 1004 , Latvia 
245 1 |a Environmentally Friendly Extraction of Bioactive Compounds from Spruce and Pine Needles to Obtain Extracts with Antioxidant and Antimicrobial Activity 
260 |b Riga Technical University  |c 2025 
513 |a Journal Article 
520 3 |a Timber harvesting of coniferous trees (the most abundant species in the Northern Hemisphere) leaves significant greenery side streams – coniferous needles and branches (pine, spruce and other species). Coniferous needles have been widely used in ethnomedicine, and recent research characterizes them as rich sources of biologically active compounds with immunostimulatory and anti-inflammation activities, as well as they are traditionally used to treat inflammation of the respiratory tract, colds and flu. However, new sustainable extraction methods should be proposed to obtain coniferous needle extracts with biomedical application potential. Classical extraction methods (stirring and heating) were used in this study and compared with ultrasonic treatment, and process duration and temperature optimisation were performed. During extraction, glycerol and propylene glycol, solvents widely used in the food and pharmaceutical industries, were used to improve the extracts’ stability. Obtained coniferous needle and branch extracts were characterized by their antiradical activities (17–82 % Trolox eq.) and total polyphenol concentration (6–22 % gallic acid eq.) was analysed. The extracts were tested for antibacterial and antifungal activity, which demonstrates activities comparable to synthetic drugs with potentially lower side effects caused by drugs. 
653 |a Side effects 
653 |a Fungicides 
653 |a Pine needles 
653 |a Forestry 
653 |a Ultrasonic processing 
653 |a Northern Hemisphere 
653 |a Leaves 
653 |a Biological activity 
653 |a Pharmaceutical industry 
653 |a Antioxidants 
653 |a Biomass 
653 |a Respiratory tract 
653 |a Vitamin E 
653 |a Antiinfectives and antibacterials 
653 |a Ethanol 
653 |a Inflammation 
653 |a Food industry 
653 |a Gallic acid 
653 |a Glycerol 
653 |a Viscosity 
653 |a Branches 
653 |a Pharmaceuticals 
653 |a Cellulose 
653 |a Biomedical materials 
653 |a Bioactive compounds 
653 |a Temperature 
653 |a Solvents 
653 |a Coniferous trees 
653 |a Immunostimulation 
653 |a Antimicrobial agents 
653 |a Polyphenols 
653 |a Antifungal activity 
653 |a Green chemistry 
653 |a Antimicrobial activity 
653 |a Propylene 
653 |a Ultrasonic imaging 
653 |a Propylene glycol 
653 |a Pine 
653 |a Environmental 
700 1 |a Arbidans Lauris  |u 1,2,6 Department of Environmental Science , University of Latvia , Jelgavas st. 1 , Riga , LV 1004 , Latvia 
700 1 |a Nikolajeva Vizma  |u Microbial Strain Collection of Latvia, Institute of Microbiology and Biotechnology , University of Latvia , Jelgavas st. 1 , Riga , LV 1004 , Latvia 
700 1 |a Maris, Lauberts  |u Latvian State Institute of Wood Chemistry , Dzerbenes st. 27 , Riga , LV 1006 , Latvia 
700 1 |a Grinfelds Uldis  |u Latvian State Forest Research Institute Silava , Riga st. 111 , Salaspils , LV 2169 , Latvia 
700 1 |a Klavins Maris  |u 1,2,6 Department of Environmental Science , University of Latvia , Jelgavas st. 1 , Riga , LV 1004 , Latvia 
773 0 |t Rigas Tehniskas Universitates Zinatniskie Raksti  |g vol. 29, no. 1 (2025), p. 184-201 
786 0 |d ProQuest  |t Engineering Database 
856 4 1 |3 Citation/Abstract  |u https://www.proquest.com/docview/3216849232/abstract/embedded/7BTGNMKEMPT1V9Z2?source=fedsrch 
856 4 0 |3 Full Text - PDF  |u https://www.proquest.com/docview/3216849232/fulltextPDF/embedded/7BTGNMKEMPT1V9Z2?source=fedsrch