Optimisation of the removal of antibiotics from aqueous environments through ultrasonic processing with α-hematite nanoparticles using response surface methodology (case study: cefixime)

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Publicado en:Applied Water Science vol. 15, no. 6 (Jun 2025), p. 132
Autor principal: Rajabizadeh, Ahmad
Otros Autores: Abdipour, Hossein, Jafari Mansoorian, Hossein
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Springer Nature B.V.
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100 1 |a Rajabizadeh, Ahmad  |u Kerman University of Medical Sciences, Department of Environmental Health Engineering, Environmental Health Engineering Research Center, Kerman, Iran (GRID:grid.412105.3) (ISNI:0000 0001 2092 9755) 
245 1 |a Optimisation of the removal of antibiotics from aqueous environments through ultrasonic processing with α-hematite nanoparticles using response surface methodology (case study: cefixime) 
260 |b Springer Nature B.V.  |c Jun 2025 
513 |a Case Study Journal Article 
520 3 |a The occurrence of contamination of emerging concerns (CECs) has turned into a significant challenge. In the present study, the elimination of Cefixime from the aquatic media was optimized. The ultrasonic method, combined through α-hematite nanoparticles, was studied using the response surface methodology (RSM). In this examination, various factors were evaluated to determine their impact, including pH levels (ranging from 5 to 11), nanoparticle dosage (0.05–0.3 g/L), contact time (10–90 min), primary Cefixime concentration (25–100 mg/L), and ultrasound wave frequencies (35–130 kHz). Nanoparticle characteristics were determined through Brunauer–Emmett–Teller (BET) and X-ray diffraction (XRD) analysis. The chemical oxygen demand (COD) was measured to monitor the removal of Cefixime. The outcomes of the data analysis revealed that the catalyst dosage and contact time were the most significant factors influencing the Cefixime removal rate. The optimal conditions determined during the experiments included a pH of 3, an ultrasound wave frequency of 37 kHz, an initial Cefixime concentration of 25 mg/L, a catalyst dosage of 0.25 g/L, and a reaction time of 90 min. Under these conditions, a COD elimination efficiency of 98.7% was attained for Cefixime. The process kinetics adhered to a pseudo-second-order (PSO) model, achieving an R2 value of 0.9905. The findings of this research demonstrate the high efficiency of the sonocatalytic removal technique in eliminating Cefixime antibiotics from aqueous solutions. 
651 4 |a Iran 
653 |a Chemical oxygen demand 
653 |a Ultrasonic methods 
653 |a Aqueous solutions 
653 |a Nanoparticles 
653 |a pH 
653 |a Cefixime 
653 |a Haematite 
653 |a Ultrasonic processing 
653 |a Catalysts 
653 |a Kinetics 
653 |a Demand analysis 
653 |a Response surface methodology 
653 |a Data analysis 
653 |a X-ray diffraction 
653 |a Antibiotics 
653 |a Dosage 
653 |a Oxygen requirement 
653 |a Aqueous environments 
653 |a Optimization 
653 |a Ultrasound 
653 |a Hematite 
653 |a Wave frequency 
653 |a Ultrasonic imaging 
653 |a Environmental 
700 1 |a Abdipour, Hossein  |u Hamadan University of Medical Sciences, Student Research Committee, Department of Environmental Health Engineering, Hamadan, Iran (GRID:grid.411950.8) (ISNI:0000 0004 0611 9280) 
700 1 |a Jafari Mansoorian, Hossein  |u Hamadan University of Medical Sciences, Department of Environmental Health Engineering, Faculty of Health and Research Center for Health Sciences, Hamadan, Iran (GRID:grid.411950.8) (ISNI:0000 0004 0611 9280) 
773 0 |t Applied Water Science  |g vol. 15, no. 6 (Jun 2025), p. 132 
786 0 |d ProQuest  |t Publicly Available Content Database 
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856 4 0 |3 Full Text  |u https://www.proquest.com/docview/3218699639/fulltext/embedded/75I98GEZK8WCJMPQ?source=fedsrch 
856 4 0 |3 Full Text - PDF  |u https://www.proquest.com/docview/3218699639/fulltextPDF/embedded/75I98GEZK8WCJMPQ?source=fedsrch