The Global Disease Burden of Hypertensive Heart Disease from 1990 to 2019: A Gender-Stratified Joinpoint Analysis †
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| Publicado en: | Journal of Clinical Medicine vol. 14, no. 12 (2025), p. 4216-4228 |
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| Otros Autores: | , , , , , , , |
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| Acceso en línea: | Citation/Abstract Full Text + Graphics Full Text - PDF |
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| 022 | |a 2077-0383 | ||
| 024 | 7 | |a 10.3390/jcm14124216 |2 doi | |
| 035 | |a 3223911621 | ||
| 045 | 2 | |b d20250101 |b d20251231 | |
| 100 | 1 | |a Noman, Khalid |u Department of Internal Medicine, St. Joseph’s University Medical Center, Paterson, NJ 07503, USA | |
| 245 | 1 | |a The Global Disease Burden of Hypertensive Heart Disease from 1990 to 2019: A Gender-Stratified Joinpoint Analysis † | |
| 260 | |b MDPI AG |c 2025 | ||
| 513 | |a Journal Article | ||
| 520 | 3 | |a This study aimed to examine global hypertensive heart disease (HHD) trends (1990–2019). Methods: We extracted data from the Global Burden of Disease (GBD) 2019 Study, encompassing 204 countries and territories. We analyzed the age-adjusted mortality rates (AAMRs), crude mortality, prevalence, years lived with disability (YLD), years of life lost (YLL), and disability-adjusted life years (DALY). Joinpoint Regression Analysis was used to calculate the Annual Percentage Change (APC), with p < 0.05 indicating statistical significance. Results were stratified by region, Socio-Demographic Index (SDI), and gender. Results: Globally, the crude mortality rate for HHD rose from 12.2 (95% UI 9.9–13.6) to 14.9 (95% UI 16.5–11.1) deaths/100,000 population (1990–2019), whereas the AAMR declined from 19.3 (95% UI 5.8–21.6) to 15.1 (95% UI 11.1–16.7). A Joinpoint Analysis revealed significant APC shifts: a decrease of −1.53% (p < 0.05) from 1990 to 2006, an increase of +0.60% (p < 0.05) from 2006 to 2015, and a subsequent decrease of −1.28% (p < 0.05) from 2006 to 2019. Eastern Europe showed the highest annual rate of change in AAMR at 0.9 (95% UI: −0.1 to 1.2), whereas the high-income Asia Pacific region experienced the largest decline at −0.66 (95% UI −0.27–−0.72). Central Asian males had an AAMR of 31.1 (95% UI 35.3–22.9) in 2019, and Sub-Saharan African females reached 38.5 (95% UI 48.4–26.3). YLL trended downward in both sexes (APC: −1.94, p < 0.05 in males; −1.81, p < 0.05 in females), yet YLD rose steadily in recent years, underscoring a growing chronic burden. The AAMR was highest in 2019 among Sub-Saharan African females, which is a particularly important area. Conclusions: Targeted strategies are essential to mitigate the escalating HHD burden. | |
| 651 | 4 | |a Eastern Europe | |
| 651 | 4 | |a Asia-Pacific region | |
| 653 | |a Health care access | ||
| 653 | |a Population | ||
| 653 | |a Software | ||
| 653 | |a Regression analysis | ||
| 653 | |a Age | ||
| 653 | |a Trends | ||
| 653 | |a Mortality | ||
| 653 | |a Gender | ||
| 653 | |a Hypertension | ||
| 653 | |a Sociodemographics | ||
| 653 | |a Regions | ||
| 653 | |a Cardiovascular disease | ||
| 653 | |a Public health | ||
| 653 | |a Morbidity | ||
| 653 | |a Females | ||
| 653 | |a Disease prevention | ||
| 653 | |a Heart | ||
| 653 | |a Ethics | ||
| 653 | |a Reproducibility | ||
| 700 | 1 | |a Munshi Hasan |u Department of Internal Medicine, St. Joseph’s University Medical Center, Paterson, NJ 07503, USA | |
| 700 | 1 | |a Abdullah, Ahmad |u Department of Cardiology, St. Joseph’s University Medical Center, Paterson, NJ 07503, USA | |
| 700 | 1 | |a Abdullah, Muhammad |u Department of Public Health and Community Medicine, Shaikh Khalifa Bin Zayed Al Nahyan Medical College, Lahore 54000, Pakistan | |
| 700 | 1 | |a Afzal, Muhammad Adil |u Department of Cardiology, St. Joseph’s University Medical Center, Paterson, NJ 07503, USA | |
| 700 | 1 | |a Qadir Sarshaar |u Department of Public Health and Community Medicine, Shaikh Khalifa Bin Zayed Al Nahyan Medical College, Lahore 54000, Pakistan | |
| 700 | 1 | |a Yezin, Shamoon |u Department of Cardiology, St. Joseph’s University Medical Center, Paterson, NJ 07503, USA | |
| 700 | 1 | |a Vasudev Rahul |u Department of Cardiology, St. Joseph’s University Medical Center, Paterson, NJ 07503, USA | |
| 700 | 1 | |a Shamoon, Fayez E |u Department of Cardiology, St. Joseph’s University Medical Center, Paterson, NJ 07503, USA | |
| 773 | 0 | |t Journal of Clinical Medicine |g vol. 14, no. 12 (2025), p. 4216-4228 | |
| 786 | 0 | |d ProQuest |t Health & Medical Collection | |
| 856 | 4 | 1 | |3 Citation/Abstract |u https://www.proquest.com/docview/3223911621/abstract/embedded/XH47U3ESDU1O47K5?source=fedsrch |
| 856 | 4 | 0 | |3 Full Text + Graphics |u https://www.proquest.com/docview/3223911621/fulltextwithgraphics/embedded/XH47U3ESDU1O47K5?source=fedsrch |
| 856 | 4 | 0 | |3 Full Text - PDF |u https://www.proquest.com/docview/3223911621/fulltextPDF/embedded/XH47U3ESDU1O47K5?source=fedsrch |