Development of a Low-Cost Multi-Physiological Signal Simulation System for Multimodal Wearable Device Calibration

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出版年:Technologies vol. 13, no. 6 (2025), p. 239-253
第一著者: Tumenkhuslen, Delgerkhaan
その他の著者: Wei, Qun, Jung Jiwoo, Lee, Sangwon, Gangoh, Na, Kim Bongjo, Kim, In-Cheol, Park, Heejoon
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MDPI AG
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024 7 |a 10.3390/technologies13060239  |2 doi 
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045 2 |b d20250101  |b d20251231 
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100 1 |a Tumenkhuslen, Delgerkhaan  |u Department of Biomedical Engineering, Graduate School of Medicine, Keimyung University, Daegu 42601, Republic of Korea; nataehei@gmail.com (T.D.); wh3533@naver.com (J.J.); mintraccon@gmail.com (S.L.); 99ngo@naver.com (G.N.); yuchibbb@naver.com (B.K.) 
245 1 |a Development of a Low-Cost Multi-Physiological Signal Simulation System for Multimodal Wearable Device Calibration 
260 |b MDPI AG  |c 2025 
513 |a Journal Article 
520 3 |a Using multimodal wearable devices to diagnose cardiovascular diseases early is essential for providing timely medical assistance, particularly in remote areas. This approach helps prevent risks and reduce mortality rates. However, prolonged use of medical devices can lead to measurement inaccuracies, necessitating calibration to maintain precision. Unfortunately, wearable devices often lack affordable calibrators that are suitable for personal use. This study introduces a low-cost simulation system for phonocardiography (PCG) and photoplethysmography (PPG) signals designed for a multimodal smart stethoscope calibration. The proposed system was developed using a multicore microprocessor (MCU), two digital-to-analog converters (DACs), an LED light, and a speaker. It synchronizes dual signals by assigning tasks based on a multitasking function. A designed time adjustment algorithm controls the pulse transit time (PTT) to simulate various cardiovascular conditions. The simulation signals are generated from preprocessed PCG and PPG signals collected during in vivo experiments. A prototype device was manufactured to evaluate performance by measuring the generated signal using an oscilloscope and a multimodal smart stethoscope. The preprocessed signals, generated signals, and measurements by the smart stethoscope were compared and evaluated through correlation analysis. The experimental results confirm that the proposed system accurately generates the features of the physiological signals and remains in phase with the original signals. 
653 |a Receivers & amplifiers 
653 |a Physiology 
653 |a Simulation 
653 |a Integrated circuits 
653 |a Accuracy 
653 |a Low cost 
653 |a Performance evaluation 
653 |a Mortality 
653 |a Pulse oximetry 
653 |a Calibration 
653 |a Multitasking 
653 |a Light emitting diodes 
653 |a Cardiovascular disease 
653 |a Wearable technology 
653 |a Wearable computers 
653 |a Medical equipment 
653 |a Medical devices 
653 |a Transit time 
653 |a Professionals 
653 |a Heart 
653 |a Blood 
653 |a Digital to analog converters 
653 |a Sound 
653 |a Correlation analysis 
700 1 |a Wei, Qun  |u Department of Biomedical Engineering, College of Engineering, Keimyung University, Daegu 42601, Republic of Korea; hjpark@kmu.ac.kr 
700 1 |a Jung Jiwoo  |u Department of Biomedical Engineering, Graduate School of Medicine, Keimyung University, Daegu 42601, Republic of Korea; nataehei@gmail.com (T.D.); wh3533@naver.com (J.J.); mintraccon@gmail.com (S.L.); 99ngo@naver.com (G.N.); yuchibbb@naver.com (B.K.) 
700 1 |a Lee, Sangwon  |u Department of Biomedical Engineering, Graduate School of Medicine, Keimyung University, Daegu 42601, Republic of Korea; nataehei@gmail.com (T.D.); wh3533@naver.com (J.J.); mintraccon@gmail.com (S.L.); 99ngo@naver.com (G.N.); yuchibbb@naver.com (B.K.) 
700 1 |a Gangoh, Na  |u Department of Biomedical Engineering, Graduate School of Medicine, Keimyung University, Daegu 42601, Republic of Korea; nataehei@gmail.com (T.D.); wh3533@naver.com (J.J.); mintraccon@gmail.com (S.L.); 99ngo@naver.com (G.N.); yuchibbb@naver.com (B.K.) 
700 1 |a Kim Bongjo  |u Department of Biomedical Engineering, Graduate School of Medicine, Keimyung University, Daegu 42601, Republic of Korea; nataehei@gmail.com (T.D.); wh3533@naver.com (J.J.); mintraccon@gmail.com (S.L.); 99ngo@naver.com (G.N.); yuchibbb@naver.com (B.K.) 
700 1 |a Kim, In-Cheol  |u Division of Cardiology, Department of Internal Medicine, Keimyung University Dongsan Hospital, Keimyung University School of Medicine, Daegu 42601, Republic of Korea; kimic@dsmc.or.kr 
700 1 |a Park, Heejoon  |u Department of Biomedical Engineering, College of Engineering, Keimyung University, Daegu 42601, Republic of Korea; hjpark@kmu.ac.kr 
773 0 |t Technologies  |g vol. 13, no. 6 (2025), p. 239-253 
786 0 |d ProQuest  |t Materials Science Database 
856 4 1 |3 Citation/Abstract  |u https://www.proquest.com/docview/3223943038/abstract/embedded/7BTGNMKEMPT1V9Z2?source=fedsrch 
856 4 0 |3 Full Text + Graphics  |u https://www.proquest.com/docview/3223943038/fulltextwithgraphics/embedded/7BTGNMKEMPT1V9Z2?source=fedsrch 
856 4 0 |3 Full Text - PDF  |u https://www.proquest.com/docview/3223943038/fulltextPDF/embedded/7BTGNMKEMPT1V9Z2?source=fedsrch