MR-link-2: pleiotropy robust cis Mendelian randomization validated in three independent reference datasets of causality

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Publicado no:	Nature Communications vol. 16, no. 1 (2025), p. 6112
Autor principal:	van der Graaf, Adriaan
Outros Autores:	Warmerdam, Robert, Auwerx, Chiara, Boltz, Toni, Boomsma, Dorret I., Brown, Andrew, Cheruiyot, Evans, Davenport, Emma E., Dupuis, Théo, Esko, Tõnu, Farzeen, Aiman, Ferrucci, Luigi, Frayling, Timothy M., Gibson, Greg, Gieger, Christian, van Greevenbroek, Marleen, Mishra, Binisha Hamal, Ikram, M. Arfan, Inouye, Michael, Jansen, Rick, Kähönen, Mika, Kukushkina, Viktorija, Lapinska, Sandra, Lehtimäki, Terho, Mägi, Reedik, Martinez-Perez, Angel, McRae, Allan F., van Meurs, Joyce, Milani, Lili, Montgomery, Grant W., Nagpal, Sini, Nauck, Matthias, Ophoff, Roel, Pasaniuc, Bogdan, Paul, Dirk S., Persyn, Elodie, Peters, Annette, Prokisch, Holger, Raitakari, Olli T., Raitoharju, Emma, Singleton, Andrew, Slagboom, Eline, Soria, José Manuel, Souto, Juan Carlos, Teumer, Alexander, Tokolyi, Alex, Veldink, Jan, Verlouw, Joost, Viñuela, Ana, Visscher, Peter M., Völker, Uwe, Weiss, Stefan, Westra, Harm-Jan, Wood, Andrew R., Xie, Manke, Võsa, Urmo, Borges, Maria Carolina, Franke, Lude, Kutalik, Zoltán
Publicado em:	Nature Publishing Group
Assuntos:	Statistics Pleiotropy Pyruvic acid Violations Datasets Quantitative trait loci Genetic variance Phenotypes Causality Metabolites Linkage disequilibrium Gene mapping Genes Blood Citric acid Heterogeneity Simulation Metabolic pathways Gene expression Risk factors Randomization Methods Robustness (mathematics) Tricarboxylic acid cycle Blood cells Meta-analysis Genetic diversity Social
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