Association of weekend catch-up sleep ratio with depressive risk: insights from NHANES 2021–2023

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Publicado en:BMC Psychiatry vol. 25 (2025), p. 1-16
Autor principal: Sun, Shilin
Otros Autores: Liu, Min, Liu, Han, Li, Runzhou, Liang, Qun, Quan, Weiwei
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Springer Nature B.V.
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Acceso en línea:Citation/Abstract
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022 |a 1471-244X 
024 7 |a 10.1186/s12888-025-07083-w  |2 doi 
035 |a 3227645506 
045 2 |b d20250101  |b d20251231 
084 |a 58489  |2 nlm 
100 1 |a Sun, Shilin 
245 1 |a Association of weekend catch-up sleep ratio with depressive risk: insights from NHANES 2021–2023 
260 |b Springer Nature B.V.  |c 2025 
513 |a Journal Article 
520 3 |a BackgroundDepression is a common global mental health issue, affecting around 3.8% of the population. It significantly impacts quality of life and social functioning, posing a major public health challenge. Sleep is a key factor influencing depression, with both sleep quality and quantity linked to mental health. However, sleep deprivation is widespread, and many people compensate by “weekend sleep recovery.” The effects of sleep deprivation and weekend recovery on depression risk are unclear, as irregular sleep patterns may worsen depressive symptoms. This study introduces the “Weekend Catch-up Sleep Ratio” (CUS ratio) to better understand the relationship between sleep patterns and depression.MethodsCross-sectional data were obtained from individuals who participated in the 2021–2023 National Health and Nutrition Examination Survey (NHANES) and had complete data on CUS and the Patient Health Questionnaire (PHQ-9). Multivariable logistic regression was performed to assess the potential independent association between depression and the CUS ratio. Additionally, smoothing curve fitting, threshold effect analysis, subgroup analysis, and interaction tests were conducted.ResultsA total of 4,656 individuals were analyzed, categorized by depression symptoms (PHQ-9 score of 10 or higher), with an overall depression risk of 12.4%. In the adjusted model, the CUS ratio was significantly positively associated with depression risk (AOR = 1.75, 95% CI: 1.25–2.45), exhibiting a nonlinear threshold effect (inflection point at 1.11). When the CUS ratio ≤ 1.11, an increase in the ratio was associated with a reduced depression risk (AOR = 0.34, 95% CI: 0.13–0.89), whereas when the CUS ratio > 1.11, each unit increase in the ratio significantly increased depression risk by 187% (AOR = 2.87, 95% CI: 1.84–4.50). Individuals with education levels of less than 9th grade, some college or an Associate of Arts (AA) degree, those who are overweight (25 ≤ BMI < 30), and those without diabetes appeared more sensitive to fluctuations in sleep patterns.In the adjusted model for the severity of depressive symptoms, the CUS ratio was significantly positively associated with depression severity (Aβ = 0.19, 95% CI: 0.09–0.28), also exhibiting a nonlinear threshold effect (inflection point at 1.11). When the CUS ratio ≤ 1.11, an increase in the ratio was associated with a reduction in depression severity (Aβ = -0.35, 95% CI: -0.62 to -0.09), whereas when the CUS ratio > 1.11, each unit increase in the ratio significantly increased depression severity (Aβ = 0.36, 95% CI: 0.24–0.49). In particular, individuals without diabetes appeared more sensitive to fluctuations in sleep patterns.ConclusionsThis study suggests that maintaining a balanced sleep pattern, with a CUS ratio between 1 and 1.11, may help reduce depression risk and promote better mental health. 
610 4 |a National Center for Health Statistics 
651 4 |a United States--US 
653 |a Diabetes 
653 |a Poverty 
653 |a Public health 
653 |a Body mass index 
653 |a Generalized linear models 
653 |a Mental health 
653 |a Mental disorders 
653 |a Questionnaires 
653 |a Suicidal ideation 
653 |a Variables 
653 |a Diabetes mellitus 
653 |a Quality of life 
653 |a Mental depression 
653 |a Sleep deprivation 
653 |a Disease prevention 
653 |a Variance analysis 
653 |a Suicides & suicide attempts 
653 |a Cross-sectional studies 
700 1 |a Liu, Min 
700 1 |a Liu, Han 
700 1 |a Li, Runzhou 
700 1 |a Liang, Qun 
700 1 |a Quan, Weiwei 
773 0 |t BMC Psychiatry  |g vol. 25 (2025), p. 1-16 
786 0 |d ProQuest  |t Health & Medical Collection 
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856 4 0 |3 Full Text  |u https://www.proquest.com/docview/3227645506/fulltext/embedded/7BTGNMKEMPT1V9Z2?source=fedsrch 
856 4 0 |3 Full Text - PDF  |u https://www.proquest.com/docview/3227645506/fulltextPDF/embedded/7BTGNMKEMPT1V9Z2?source=fedsrch