Comparison of Myocardial Perfusion Scintigraphy Before and After Coronary Bypass Surgery

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Publicat a:Pakistan Armed Forces Medical Journal vol. 75, no. 3 (Jun 2025), p. 454-459
Autor principal: Malik, Asad
Altres autors: Hussain, Fida, Aleena Tariq, Muhammad Adil, Hussain, Mehmood, Zeeshan Sikandar
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Army Medical Corps
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100 1 |a Malik, Asad 
245 1 |a Comparison of Myocardial Perfusion Scintigraphy Before and After Coronary Bypass Surgery 
260 |b Army Medical Corps  |c Jun 2025 
513 |a Journal Article 
520 3 |a Objective: To study the change in left ventricular perfusion as well as functional parameters before and after Coronary Artery Bypass Grafting (CABG) using myocardial perfusion scintigraphy. Study Design: Prospective observational study. Place and Duration of Study: Nuclear Medical Centre, Armed Forces Institute of Pathology, Rawalpindi, from Feb 2019 to Jan 2022. Methodology: A total of 42 patients, scheduled for CABG, underwent myocardial perfusion scintigraphy (MPS) using 99mTc-sestamibi, before and 8-12 weeks after surgery. Pre and post operatively, left ventricular relative perfusion and functional parameters were analyzed using commercially available software by two independent nuclear physicians. Results: Among the enrolled patients (n=42), 38(90.5%) were male while 4(9.5%) were female with mean age of 61.04±8.82 years. Left ventricular ejection fraction improved and was found to be statistically significant (38.93±8.19 to 46.26±10.46, p-value <0.01). Similarly, wall motion increased significantly in anterior and lateral segments with concomitant decrease in septal wall motion. A correlation was observed post-operatively between change in ejection fraction and wall motion (r=0.76) while significantly improved post-CABG radiotracer uptake was seen in almost all myocardial segments which showed reversible ischemia with resting perfusion ≥50% in 97 segments with fixed perfusion defects on pre-CABG resting perfusion, but ≤50% did not show any significant improvement, while 5 segments with pre-CABG resting perfusion ≤50% showed improvement on post-CABG MPS. Conclusion: There is significant improvement in left ventricular perfusion and functional parameters after CABG as assessed by myocardial perfusion scintigraphy. 
653 |a Adenosine 
653 |a Tomography 
653 |a Diabetes 
653 |a Vein & artery diseases 
653 |a Surgery 
653 |a Thyroid diseases 
653 |a Autoimmune diseases 
653 |a Ejection fraction 
653 |a Coronary vessels 
653 |a Hypertension 
653 |a Surgical outcomes 
653 |a Females 
653 |a Ischemia 
653 |a Liver diseases 
653 |a Cardiology 
700 1 |a Hussain, Fida 
700 1 |a Aleena Tariq 
700 1 |a Muhammad Adil 
700 1 |a Hussain, Mehmood 
700 1 |a Zeeshan Sikandar 
773 0 |t Pakistan Armed Forces Medical Journal  |g vol. 75, no. 3 (Jun 2025), p. 454-459 
786 0 |d ProQuest  |t Health & Medical Collection 
856 4 1 |3 Citation/Abstract  |u https://www.proquest.com/docview/3229487971/abstract/embedded/Q8Z64E4HU3OH5N8U?source=fedsrch 
856 4 0 |3 Full Text  |u https://www.proquest.com/docview/3229487971/fulltext/embedded/Q8Z64E4HU3OH5N8U?source=fedsrch 
856 4 0 |3 Full Text - PDF  |u https://www.proquest.com/docview/3229487971/fulltextPDF/embedded/Q8Z64E4HU3OH5N8U?source=fedsrch