Prognostic Significance of the Comprehensive Biomarker Analysis in Colorectal Cancer
Պահպանված է:
| Հրատարակված է: | Life vol. 15, no. 7 (2025), p. 1100-1132 |
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| Հիմնական հեղինակ: | |
| Այլ հեղինակներ: | , , , , , , , , , |
| Հրապարակվել է: |
MDPI AG
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| Խորագրեր: | |
| Առցանց հասանելիություն: | Citation/Abstract Full Text + Graphics Full Text - PDF |
| Ցուցիչներ: |
Չկան պիտակներ, Եղեք առաջինը, ով նշում է այս գրառումը!
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MARC
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| 001 | 3233228380 | ||
| 003 | UK-CbPIL | ||
| 022 | |a 2075-1729 | ||
| 024 | 7 | |a 10.3390/life15071100 |2 doi | |
| 035 | |a 3233228380 | ||
| 045 | 2 | |b d20250101 |b d20251231 | |
| 084 | |a 231529 |2 nlm | ||
| 100 | 1 | |a Potievskaya Vera |u Russian Medical Academy of Postgraduate Education of Federal Scientific and Clinical Center for Specialized Medical Assistance and Medical Technologies of the Federal Medical Biological Agency, Volokolamskoye Shosse, 91, 125371 Moscow, Russia; vera.pot@mail.ru | |
| 245 | 1 | |a Prognostic Significance of the Comprehensive Biomarker Analysis in Colorectal Cancer | |
| 260 | |b MDPI AG |c 2025 | ||
| 513 | |a Journal Article | ||
| 520 | 3 | |a Colorectal carcinoma remains one of the primary contributors to cancer deaths; however, it is also considered a preventable type of cancer, because the prognosis of the disease is directly dependent on its timely detection. Developing accurate risk prediction models for colorectal cancer is crucial for identifying individuals at both low and high risk, as risk stratification determines the need for additional interventions, which carry their own risks. The development of new non-invasive diagnostic methods based on biomaterial analysis, alongside standard diagnostic techniques such as colonoscopy with biopsy, computed tomography scanning, and magnetic resonance imaging, can address multiple objectives: improving screening accuracy, providing a comprehensive assessment of minimal residual disease, identifying patients at a high risk of colorectal cancer, and evaluating the effectiveness of ongoing treatments. The lack of sensitive diagnostic methods drives contemporary research toward the discovery of new tools for detecting tumor cells, particularly through the examination of biological materials, including blood, exhaled air, and tumor tissue itself. In this article, we analyze current studies regarding biomarkers in colorectal cancer and prognostic significance. | |
| 653 | |a DNA methylation | ||
| 653 | |a Volatile organic compounds--VOCs | ||
| 653 | |a Minimal residual disease | ||
| 653 | |a Accuracy | ||
| 653 | |a Magnetic resonance imaging | ||
| 653 | |a Biological materials | ||
| 653 | |a Biopsy | ||
| 653 | |a Cancer therapies | ||
| 653 | |a Mutation | ||
| 653 | |a Tumors | ||
| 653 | |a Metabolism | ||
| 653 | |a Biomaterials | ||
| 653 | |a Colorectal cancer | ||
| 653 | |a Risk | ||
| 653 | |a Prediction models | ||
| 653 | |a Tumor cells | ||
| 653 | |a Medical prognosis | ||
| 653 | |a Surgery | ||
| 653 | |a Computed tomography | ||
| 653 | |a Biomedical materials | ||
| 653 | |a Cancer | ||
| 653 | |a Biomarkers | ||
| 653 | |a Colorectal carcinoma | ||
| 653 | |a Methods | ||
| 653 | |a Precision medicine | ||
| 653 | |a Social | ||
| 700 | 1 | |a Tyukanova Elizaveta |u Oncology Department of Antitumor Drug Therapy, Sechenov University Clinical Hospital No.4, I.M. Sechenov First Moscow State Medical University, Str. Dovatora, 15, Bldg. 2, 119048 Moscow, Russia; fatyanova_e_s@staff.sechenov.ru (A.F.); kholstinina.anna@mail.ru (A.K.); sagekthadley@gmail.com (E.P.) | |
| 700 | 1 | |a Sekacheva Marina |u World-Class Reserch Centre «Digital Biodesign and Personalized Healthcare», I.M. Sechenov First Moscow State Medical University (Sechenov University), Str. Bolshaya Pirogovskaya, 6, Bldg. 1, 119991 Moscow, Russia; sekacheva_m_i@staff.sechenov.ru | |
| 700 | 1 | |a Zaki, Fashafsha |u P. Hertsen Moscow Oncology Research Institute—Branch or the Federal State Budgetary Institution “National Medical Research Radiological Centre” of the Ministry of Health of the Russian Federation, 2nd Botkinsky Proezd, 3, 125284 Moscow, Russia; elena24936@yandex.ru | |
| 700 | 1 | |a Fatyanova Anastasia |u Oncology Department of Antitumor Drug Therapy, Sechenov University Clinical Hospital No.4, I.M. Sechenov First Moscow State Medical University, Str. Dovatora, 15, Bldg. 2, 119048 Moscow, Russia; fatyanova_e_s@staff.sechenov.ru (A.F.); kholstinina.anna@mail.ru (A.K.); sagekthadley@gmail.com (E.P.) | |
| 700 | 1 | |a Potievskiy Mikhail |u Federal State Budgetary Institution “National Medical Research Radiological Centre” of the Ministry of Health of the Russian Federation, 4, Koroleva Street, 249036 Obninsk, Russia; potievskiymikhail@gmail.com (M.P.); dr.shegai@mail.ru (P.S.); kaprin@mail.ru (A.K.) | |
| 700 | 1 | |a Kononova Elena |u P. Hertsen Moscow Oncology Research Institute—Branch or the Federal State Budgetary Institution “National Medical Research Radiological Centre” of the Ministry of Health of the Russian Federation, 2nd Botkinsky Proezd, 3, 125284 Moscow, Russia; elena24936@yandex.ru | |
| 700 | 1 | |a Kholstinina Anna |u Oncology Department of Antitumor Drug Therapy, Sechenov University Clinical Hospital No.4, I.M. Sechenov First Moscow State Medical University, Str. Dovatora, 15, Bldg. 2, 119048 Moscow, Russia; fatyanova_e_s@staff.sechenov.ru (A.F.); kholstinina.anna@mail.ru (A.K.); sagekthadley@gmail.com (E.P.) | |
| 700 | 1 | |a Polishchuk Ekatherina |u Oncology Department of Antitumor Drug Therapy, Sechenov University Clinical Hospital No.4, I.M. Sechenov First Moscow State Medical University, Str. Dovatora, 15, Bldg. 2, 119048 Moscow, Russia; fatyanova_e_s@staff.sechenov.ru (A.F.); kholstinina.anna@mail.ru (A.K.); sagekthadley@gmail.com (E.P.) | |
| 700 | 1 | |a Shegai, Peter |u Federal State Budgetary Institution “National Medical Research Radiological Centre” of the Ministry of Health of the Russian Federation, 4, Koroleva Street, 249036 Obninsk, Russia; potievskiymikhail@gmail.com (M.P.); dr.shegai@mail.ru (P.S.); kaprin@mail.ru (A.K.) | |
| 700 | 1 | |a Kaprin Andrey |u Federal State Budgetary Institution “National Medical Research Radiological Centre” of the Ministry of Health of the Russian Federation, 4, Koroleva Street, 249036 Obninsk, Russia; potievskiymikhail@gmail.com (M.P.); dr.shegai@mail.ru (P.S.); kaprin@mail.ru (A.K.) | |
| 773 | 0 | |t Life |g vol. 15, no. 7 (2025), p. 1100-1132 | |
| 786 | 0 | |d ProQuest |t Biological Science Database | |
| 856 | 4 | 1 | |3 Citation/Abstract |u https://www.proquest.com/docview/3233228380/abstract/embedded/L8HZQI7Z43R0LA5T?source=fedsrch |
| 856 | 4 | 0 | |3 Full Text + Graphics |u https://www.proquest.com/docview/3233228380/fulltextwithgraphics/embedded/L8HZQI7Z43R0LA5T?source=fedsrch |
| 856 | 4 | 0 | |3 Full Text - PDF |u https://www.proquest.com/docview/3233228380/fulltextPDF/embedded/L8HZQI7Z43R0LA5T?source=fedsrch |