Influence of Uncertainties in Optode Positions on Self-Calibrating or Dual-Slope Diffuse Optical Measurements

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Publicado no:Photonics vol. 12, no. 7 (2025), p. 697-720
Autor principal: Blaney Giles
Outros Autores: Sassaroli Angelo, Das Tapan, Fantini, Sergio
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MDPI AG
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100 1 |a Blaney Giles  |u Department of Biomedical Engineering, Tufts University, 4 Colby Street, Medford, MA 02155, USA; angelo.sassaroli@tufts.edu (A.S.); sergio.fantini@tufts.edu (S.F.) 
245 1 |a Influence of Uncertainties in Optode Positions on Self-Calibrating or Dual-Slope Diffuse Optical Measurements 
260 |b MDPI AG  |c 2025 
513 |a Journal Article 
520 3 |a Self-calibrating and dual-slope measurements have been used in the field of diffuse optics for robust assessment of absolute values or temporal changes in the optical properties of highly scattering media and biological tissue. These measurements employ optical probes with a minimum of two source positions and a minimum of two detector positions. This work focuses on a quantitative analysis of the impact of errors in these source and detector positions on the assessment of optical properties. We considered linear, trapezoidal, and rectangular optode arrangements and theoretical computations based on diffusion theory for semi-infinite homogeneous media. We found that uncertainties in optodes’ positions may have a greater impact on measurements of absolute scattering versus absorption coefficients. For example, a 4.1% and 19% average error in absolute absorption and scattering, respectively, can be expected by displacing every optode in a linear arrangement by 1 mm in any direction. The impact of optode position errors is typically smaller for measurements of absorption changes. In each geometrical arrangement (linear, trapezoid, rectangular), we identify the direction of the position uncertainty for each optode that has minimal impact on the optical measurements. These results can guide the optimal design of optical probes for self-calibrating and dual-slope measurements. 
653 |a Position measurement 
653 |a Optical properties 
653 |a Probes 
653 |a Optics 
653 |a Spectrum analysis 
653 |a Scattering 
653 |a Absorption 
653 |a Calibration 
653 |a Sensors 
653 |a Diffusion theory 
653 |a Impact analysis 
653 |a Tissues 
653 |a Absorptivity 
653 |a Optical measurement 
653 |a Uncertainty 
653 |a Position errors 
700 1 |a Sassaroli Angelo  |u Department of Biomedical Engineering, Tufts University, 4 Colby Street, Medford, MA 02155, USA; angelo.sassaroli@tufts.edu (A.S.); sergio.fantini@tufts.edu (S.F.) 
700 1 |a Das Tapan  |u Department of Power Electronics & Intrumentation Engineering, Jorhat Institute of Science and Technology, Chenijaan, Jorhat 785010, Assam, India; td.pei@jist.ac.in 
700 1 |a Fantini, Sergio  |u Department of Biomedical Engineering, Tufts University, 4 Colby Street, Medford, MA 02155, USA; angelo.sassaroli@tufts.edu (A.S.); sergio.fantini@tufts.edu (S.F.) 
773 0 |t Photonics  |g vol. 12, no. 7 (2025), p. 697-720 
786 0 |d ProQuest  |t Advanced Technologies & Aerospace Database 
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