Data Mining–Based Model for Computer-Aided Diagnosis of Autism and Gelotophobia: Mixed Methods Deep Learning Approach

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Vydáno v:JMIR Formative Research vol. 9 (2025), p. e72115-e72131
Hlavní autor: Eldawansy, Mohamed
Další autoři: Hazem El Bakry, Shohieb, Samaa M
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JMIR Publications
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022 |a 2561-326X 
024 7 |a 10.2196/72115  |2 doi 
035 |a 3241585063 
045 2 |b d20250101  |b d20251231 
100 1 |a Eldawansy, Mohamed 
245 1 |a Data Mining–Based Model for Computer-Aided Diagnosis of Autism and Gelotophobia: Mixed Methods Deep Learning Approach 
260 |b JMIR Publications  |c 2025 
513 |a Journal Article 
520 3 |a Background:Gelotophobia, the fear of being laughed at, is a social anxiety condition that affects approximately 6% of neurotypical individuals and up to 45% of those with autism spectrum disorder (ASD). This comorbidity can significantly impair the quality of life, particularly in adolescents with high-functioning ASD, where the prevalence reaches 41.98%. Accurate and automated detection tools could enhance early diagnosis and intervention.Objective:This study aimed to develop a deep learning–based diagnostic system that integrates facial emotion recognition with validated questionnaires to detect gelotophobia in individuals with or without ASD.Methods:The system was trained to identify ASD status using a balanced dataset of 2932 facial images (n=1466; 50% from individuals with ASD and n=1466; 50% from neurotypical individuals). The images were processed using the DeepFace library to extract facial features, which were then used as input for the deep learning classifier. After identifying ASD status, the same images were further analyzed using the pretrained DeepFace model to evaluate facial expressions for signs of gelotophobia. In cases where facial cues were ambiguous, the GELOPH<15> questionnaire, consisting of 15 items, was administered to confirm the diagnosis The system was fully implemented using the Python programming language. Deep learning models were developed using libraries such as PyTorch for training the multilayer perceptron classifier, while CUDA was used to accelerate computations on compatible graphics processing units. Additional libraries from the Python programming language, such as scikit-learn, NumPy, and Pandas, were used for preprocessing, model evaluation, and data manipulation. DeepFace was integrated using its Python application programming interface for facial recognition and emotion classification.Results:The dataset comprised 2932 facial images collected from platforms such as Kaggle and ASD-related websites, including 1466 (50%) images of children with ASD and 1466 (50%) images of neurotypical children. The dataset was split into 2653 (90.48%) training samples and 279 (9.51%) testing samples, with each image contributing 100,352 extracted features. We applied various machine learning models for ASD identification. The system achieved an overall prediction accuracy of 92% across both training and testing datasets, with the multilayer perceptron model demonstrating the highest testing accuracy. The system successfully classified gelotophobia in cases where facial expressions were clear. However, in cases of ambiguous facial cues, the DeepFace model alone was insufficient. Incorporating the GELOPH<15> questionnaire improved diagnostic reliability and consistency.Conclusions:This study demonstrates the effectiveness of combining deep learning techniques with validated diagnostic tools for detecting gelotophobia, particularly in individuals with ASD. The high accuracy achieved highlights the system’s potential for clinical and research applications, contributing to the improved understanding and management of gelotophobia among groups considered socially vulnerable. Future research could expand the system’s applications to broader psychological assessments. 
653 |a Machine learning 
653 |a Behavior 
653 |a Accuracy 
653 |a Deep learning 
653 |a Artificial intelligence 
653 |a Social interaction 
653 |a Data mining 
653 |a Quantitative psychology 
653 |a Intervention 
653 |a Neural networks 
653 |a Questionnaires 
653 |a Autistic children 
653 |a Integrated approach 
653 |a Automation 
653 |a Facial recognition technology 
653 |a Emotions 
653 |a Social anxiety 
700 1 |a Hazem El Bakry 
700 1 |a Shohieb, Samaa M 
773 0 |t JMIR Formative Research  |g vol. 9 (2025), p. e72115-e72131 
786 0 |d ProQuest  |t Health & Medical Collection 
856 4 1 |3 Citation/Abstract  |u https://www.proquest.com/docview/3241585063/abstract/embedded/H09TXR3UUZB2ISDL?source=fedsrch 
856 4 0 |3 Full Text + Graphics  |u https://www.proquest.com/docview/3241585063/fulltextwithgraphics/embedded/H09TXR3UUZB2ISDL?source=fedsrch 
856 4 0 |3 Full Text - PDF  |u https://www.proquest.com/docview/3241585063/fulltextPDF/embedded/H09TXR3UUZB2ISDL?source=fedsrch