Integrating hypertension control into post-stroke neurorehabilitation: a randomized trial on cognitive and motor recovery outcomes
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| Udgivet i: | Revista Latinoamericana de Hipertension vol. 20, no. 4 (2025), p. 286-294 |
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Sociedad Latinoamericana de Hipertension
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| 045 | 2 | |b d20251001 |b d20251231 | |
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| 100 | 1 | |a Sadoqat, Saidova |u Bukhara State Medical Institute, Bukhara, Uzbekistan | |
| 245 | 1 | |a Integrating hypertension control into post-stroke neurorehabilitation: a randomized trial on cognitive and motor recovery outcomes | |
| 260 | |b Sociedad Latinoamericana de Hipertension |c 2025 | ||
| 513 | |a Journal Article | ||
| 520 | 3 | |a With a yearly incidence of greater than 150 cases per 100,000 population in Uzbekistan, stroke is a public health problem, with 40% of survivors of stroke having hypertension. This randomized controlled trial in 120 patients (mean age 58 ± 8 years) examined the influence of adding targeted blood pressure control (with a goal systolic blood pressure <130 mmHg) to post-stroke neurorehabilitation protocols. Two groups of intervention patients (standard rehabilitation + blood pressure control) and one control patient group (standard rehabilitation only) were randomly allocated, and patients' outcomes were assessed by means of MMSE (cognitive) and FIM (motor) tests after 3 and 6 months. The intervention group was 25% better in cognitive scores (12% in the control group, p < 0.01) and 40% better in motor scores (FIM score: 85 ± 10 vs. 72 ± 8 in the control group, p < 0.03) at 6 months. In addition, 78% of the patients of the intervention group reached the goal blood pressure (<130/80 mmHg), whereas this achievement was 35% in the control group. The findings show that active control of blood pressure, not just as an adjunctive therapy, but also as a component of rehabilitation protocols for post-stroke patients, highly promotes cognitive-motor recovery and its introduction into the Uzbek healthcare system is advisable. Con una incidencia anual superior a 150 casos por cada 100.000 habitantes en Uzbekistan, el ictus es un problema de salud publica, y el 40% de los supervivientes presentan hipertension. Este ensayo controlado aleatorizado, realizado en 120 pacientes (edad media de 58 + 8 años), examinó la influencia de añadir un control objetivo de la presión arterial (con un objetivo de presión arterial sistólica <130 mmHg) a los protocolos de neurorrehabilitación postictus. Se asignaron aleatoriamente dos grupos de pacientes de intervención (rehabilitación estándar + control de la presión arterial) y un grupo de pacientes control (solo rehabilitación estándar). Los resultados de los pacientes se evaluaron mediante las pruebas MMSE (cognitiva) y FIM (motora) después de 3 y 6 meses. El grupo de intervención presentó una mejora del 25 % en las puntuaciones cognitivas (12 % en el grupo control, р < 0,01) y del 40 % en las puntuaciones motoras (puntuación FIM: 85 + 10 frente a 72 + 8 en el grupo control, p < 0,03) a los 6 meses. Además, el 78 % de los pacientes del grupo de intervención alcanzó la presión arterial objetivo (<130/80 mmHg), mientras que este logro fue del 35 % en el grupo control. Los hallazgos muestran que el control activo de la presión arterial, no solo como terapia complementaria, sino también como componente de los protocolos de rehabilitación para pacientes que han sufrido un ictus, promueve considerablemente la recuperación cognitivo-motora, y su introducción en el sistema sanitario uzbeko es recomendable. | |
| 651 | 4 | |a Uzbekistan | |
| 653 | |a Neurogenesis | ||
| 653 | |a Rehabilitation | ||
| 653 | |a Stroke | ||
| 653 | |a Health care policy | ||
| 653 | |a Hypotheses | ||
| 653 | |a Blood pressure | ||
| 653 | |a Intervention | ||
| 653 | |a Hypertension | ||
| 700 | 1 | |a Surayyo, Umirova |u PhD, Samarkand State Medical University, 140100 Samarkand, Uzbekistan | |
| 700 | 1 | |a Shoxsanam, Bebitova |u Department of Medical Rehabilitation, Sports Medicine and Traditional Medicine, Samarkand State Medical University, 140100 Samarkand, Uzbekistan | |
| 700 | 1 | |a Nigina, Rustamova |u Bukhara State Medical Institute, Bukhara, Uzbekistan | |
| 700 | 1 | |a Shahnoza, Alimova |u Bukhara State Medical Institute, Bukhara, Uzbekistan | |
| 700 | 1 | |a Dadaxon, Abdullayev | |
| 700 | 1 | |a Matmuratov, Azizbek | |
| 773 | 0 | |t Revista Latinoamericana de Hipertension |g vol. 20, no. 4 (2025), p. 286-294 | |
| 786 | 0 | |d ProQuest |t Health & Medical Collection | |
| 856 | 4 | 1 | |3 Citation/Abstract |u https://www.proquest.com/docview/3245446059/abstract/embedded/7BTGNMKEMPT1V9Z2?source=fedsrch |
| 856 | 4 | 0 | |3 Full Text |u https://www.proquest.com/docview/3245446059/fulltext/embedded/7BTGNMKEMPT1V9Z2?source=fedsrch |
| 856 | 4 | 0 | |3 Full Text - PDF |u https://www.proquest.com/docview/3245446059/fulltextPDF/embedded/7BTGNMKEMPT1V9Z2?source=fedsrch |