Metastatic hepatocellular carcinoma to the pelvis and vertebrae in a patient with chronic hepatitis ‘C’ with unknown primary
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| Publicado en: | BMJ Case Reports vol. 2015 (Sep 2025), p. bcr2014207249 |
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| Otros Autores: | , , |
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BMJ Publishing Group LTD
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| Acceso en línea: | Citation/Abstract Full Text + Graphics Full Text - PDF |
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MARC
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| 022 | |a 1757-790X | ||
| 024 | 7 | |a 10.1136/bcr-2014-207249 |2 doi | |
| 035 | |a 3254034733 | ||
| 045 | 2 | |b d20250901 |b d20250930 | |
| 084 | |a 269832 |2 nlm | ||
| 100 | 1 | |a Abbas Syed Hussain |u Department of Medicine , Khyber Teaching Hospital , Peshawar, Khyber Pakhtunkhwa , Pakistan | |
| 245 | 1 | |a Metastatic hepatocellular carcinoma to the pelvis and vertebrae in a patient with chronic hepatitis ‘C’ with unknown primary | |
| 260 | |b BMJ Publishing Group LTD |c Sep 2025 | ||
| 513 | |a Journal Article Case Study | ||
| 520 | 3 | |a A 54-year-old man infected with hepatitis C virus presented to us with pain in the right iliac fossa radiating to the back and right thigh for the past 2 months. Imaging of the abdomen and pelvis was performed, which revealed a soft tissue mass adherent to right iliac blade and right ala of sacrum. Trucut biopsy of the mass was performed and immunohistochemical stains Glypican-3 and Hep-par 1 were used for histopathological analysis, which diagnosed the mass as hepatocellular carcinoma. This is a unique case of metastasis of hepatocellular carcinoma to the bone in which imaging of the liver did not show any primary lesion. Liver function tests showed that aspartate transaminase and alanine transaminase were twice the normal range with a high viral load and significantly raised serum α-fetoprotein. The patient was treated with intravenous 5-flourouracil and radiotherapy as a palliative measure with only moderate clinical improvement. | |
| 653 | |a Vertebrae | ||
| 653 | |a Medical diagnosis | ||
| 653 | |a Pain | ||
| 653 | |a Abdomen | ||
| 653 | |a Liver cancer | ||
| 653 | |a Metastasis | ||
| 653 | |a Medical imaging | ||
| 653 | |a Hepatitis C | ||
| 653 | |a Heparan sulfate | ||
| 653 | |a Scintigraphy | ||
| 653 | |a Radiation | ||
| 653 | |a Stains & staining | ||
| 653 | |a Biopsy | ||
| 700 | 1 | |a Khan Muhammad Zia Ul Islam |u Department of Medicine , Khyber Teaching Hospital , Peshawar, Khyber Pakhtunkhwa , Pakistan | |
| 700 | 1 | |a Ijaz Muhammad |u Department of Medicine , Khyber Teaching Hospital , Peshawar, Khyber Pakhtunkhwa , Pakistan | |
| 700 | 1 | |a Hussain Syed Jawad Akhtar |u IRNUM , Peshawar, Khyber Pakhtunkhwa , Pakistan | |
| 773 | 0 | |t BMJ Case Reports |g vol. 2015 (Sep 2025), p. bcr2014207249 | |
| 786 | 0 | |d ProQuest |t Health & Medical Collection | |
| 856 | 4 | 1 | |3 Citation/Abstract |u https://www.proquest.com/docview/3254034733/abstract/embedded/J7RWLIQ9I3C9JK51?source=fedsrch |
| 856 | 4 | 0 | |3 Full Text + Graphics |u https://www.proquest.com/docview/3254034733/fulltextwithgraphics/embedded/J7RWLIQ9I3C9JK51?source=fedsrch |
| 856 | 4 | 0 | |3 Full Text - PDF |u https://www.proquest.com/docview/3254034733/fulltextPDF/embedded/J7RWLIQ9I3C9JK51?source=fedsrch |