Risk of Atrial Fibrillation and Stroke in Patients with Hypertrophic Obstructive Cardiomyopathy Treated by Modified Morrow Septal Myectomy: Reports of a Propensity Score Matching Cohort
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| Publicat a: | Journal of Cardiovascular Development and Disease vol. 12, no. 9 (2025), p. 321-333 |
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| Autor principal: | |
| Altres autors: | , , , , , , |
| Publicat: |
MDPI AG
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| Accés en línia: | Citation/Abstract Full Text + Graphics Full Text - PDF |
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| LEADER | 00000nab a2200000uu 4500 | ||
|---|---|---|---|
| 001 | 3254540441 | ||
| 003 | UK-CbPIL | ||
| 022 | |a 2308-3425 | ||
| 024 | 7 | |a 10.3390/jcdd12090321 |2 doi | |
| 035 | |a 3254540441 | ||
| 045 | 2 | |b d20250101 |b d20251231 | |
| 100 | 1 | |a Yi-Xi, Zou |u Department of Cardiac Surgery, Beijing Anzhen Hospital, Capital Medical University, Beijing 100029, China | |
| 245 | 1 | |a Risk of Atrial Fibrillation and Stroke in Patients with Hypertrophic Obstructive Cardiomyopathy Treated by Modified Morrow Septal Myectomy: Reports of a Propensity Score Matching Cohort | |
| 260 | |b MDPI AG |c 2025 | ||
| 513 | |a Journal Article | ||
| 520 | 3 | |a Background: A modified Morrow septal myectomy (MMSM) is one of the main treatment methods for obstructive hypertrophic cardiomyopathy (OHCM). Our aim was to study the impact of MMSM on the risk of AF and stroke in OHCM patients. Methods and Results: From 1 January 2014 to 31 December 2020, 6426 patients with obstructive HCM (OHCM) were selected from the Beijing Municipal Health Commission Information Center (BMHCIC) datasets (mean age: 54.3 years; 43.8% female). After propensity score matching, 3780 patients were selected, including 1890 who received MMSM (Group 1) and 1890 who did not receive any surgery (Group 2). During a median of 0.8 (interquartile range [IQR]: 0.1, 2.7) years of follow-up after discharge from the hospital, stroke risk was lower in Group 1 compared to Group 2 (aHR: 0.4, 95%CI: 0.2–0.6, p < 0.001), and the results were further confirmed by Kaplan–Meier analyses (p < 0.001). There was no statistically significant difference in the risk of AF (aHR: 1.0, 95%CI: 0.7–1.5, p = 0.991). The risk of AF decreased in the first 6 years since receiving MMSM and then sharply increased beyond 6 years after MMSM according to Kaplan–Meier analyses. Conclusions: MMSM is associated with a decreased risk of stroke in OHCM patients. The risk of AF decreased in the first 6 years since receiving MMSM and then sharply increased beyond 6 years after MMSM. | |
| 610 | 4 | |a New York Heart Association | |
| 651 | 4 | |a China | |
| 651 | 4 | |a Beijing China | |
| 651 | 4 | |a New York | |
| 651 | 4 | |a United States--US | |
| 653 | |a Hospitals | ||
| 653 | |a Medical records | ||
| 653 | |a Cardiomyopathy | ||
| 653 | |a Stroke | ||
| 653 | |a Cardiac arrhythmia | ||
| 653 | |a Surgery | ||
| 653 | |a Electrocardiography | ||
| 700 | 1 | |a Xi-Lin, Zhang |u Cardiovascular Center, Beijing Tongren Hospital, Capital Medical University, Beijing 100176, China | |
| 700 | 1 | |a Jian-Peng, Zheng |u Beijing Municipal Health Commission Information Center, Beijing 100054, China | |
| 700 | 1 | |a Lu, Feng |u Beijing Municipal Health Commission Information Center, Beijing 100054, China | |
| 700 | 1 | |a Lip Gregory Y. H. |u Liverpool Centre for Cardiovascular Science at University of Liverpool, Liverpool John Moores Universtiy and Liverpool Heart &amp; Chest Hospital, Liverpool L69 3BX, UK; gregory.lip@liverpool.ac.uk | |
| 700 | 1 | |a Bai, Ying |u Cardiovascular Center, Beijing Tongren Hospital, Capital Medical University, Beijing 100176, China | |
| 700 | 1 | |a Yu-Feng, Sun |u Clinical Medical Laboratory, Beijing Tongren Hospital, Capital Medical University, Beijing 100176, China | |
| 700 | 1 | |a Wei-Hua, Guo |u Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing 101121, China | |
| 773 | 0 | |t Journal of Cardiovascular Development and Disease |g vol. 12, no. 9 (2025), p. 321-333 | |
| 786 | 0 | |d ProQuest |t Health & Medical Collection | |
| 856 | 4 | 1 | |3 Citation/Abstract |u https://www.proquest.com/docview/3254540441/abstract/embedded/J7RWLIQ9I3C9JK51?source=fedsrch |
| 856 | 4 | 0 | |3 Full Text + Graphics |u https://www.proquest.com/docview/3254540441/fulltextwithgraphics/embedded/J7RWLIQ9I3C9JK51?source=fedsrch |
| 856 | 4 | 0 | |3 Full Text - PDF |u https://www.proquest.com/docview/3254540441/fulltextPDF/embedded/J7RWLIQ9I3C9JK51?source=fedsrch |