Fast hierarchical processing of orthographic and semantic parafoveal information during natural reading

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Publicado en:Nature Communications vol. 16, no. 1 (2025), p. 8893-8905
Autor principal: Wang, Lijuan
Otros Autores: Frisson, Steven, Pan, Yali, Jensen, Ole
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Nature Publishing Group
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Acceso en línea:Citation/Abstract
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022 |a 2041-1723 
024 7 |a 10.1038/s41467-025-63916-y  |2 doi 
035 |a 3258272726 
045 2 |b d20250101  |b d20251231 
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100 1 |a Wang, Lijuan  |u Centre for Human Brain Health, School of Psychology, University of Birmingham, Birmingham, UK (ROR: https://ror.org/03angcq70) (GRID: grid.6572.6) (ISNI: 0000 0004 1936 7486) 
245 1 |a Fast hierarchical processing of orthographic and semantic parafoveal information during natural reading 
260 |b Nature Publishing Group  |c 2025 
513 |a Journal Article 
520 3 |a In reading, information from parafoveal words is extracted before direct fixation; however, it is debated whether this processing is restricted to orthographic features or also encompasses semantics. Moreover, the neuronal mechanisms supporting parafoveal processing remain poorly understood. We co-registered MEG and eye-tracking data in a natural reading paradigm to uncover the timing and brain regions involved in parafoveal processing. Representational similarity analysis revealed that parafoveal orthographic neighbours (e.g., “writer” vs. “waiter”) showed higher representational similarity than non-neighbours (e.g., “writer” vs. “police”), emerging ~68 ms after fixation onset on the preceding word (e.g., “clever”) in the visual word form area. Similarly, parafoveal semantic neighbours (e.g., “writer” vs. “author”) exhibited increased representational similarity at ~137 ms in the left inferior frontal gyrus. Importantly, the degree of orthographic and semantic parafoveal processing was correlated with individual reading speed. Our findings suggest fast hierarchical processing of parafoveal words across distinct brain regions, enhancing reading efficiency.Combining MEG, eye-tracking, and representational similarity analysis, this study shows that readers rapidly and sequentially extract orthographic and semantic information from upcoming words before fixation, supporting efficient reading. 
653 |a Writers 
653 |a Similarity 
653 |a Design of experiments 
653 |a Eye 
653 |a Words (language) 
653 |a Brain 
653 |a Brain research 
653 |a Frontal gyrus 
653 |a Tracking 
653 |a Eye movements 
653 |a Magnetoencephalography 
653 |a Orthography 
653 |a Semantics 
653 |a Semantic features 
653 |a Fixation 
653 |a Semantic processing 
653 |a Information processing 
653 |a Reading rate 
653 |a Reading 
653 |a Data processing 
653 |a Neighbors 
653 |a Regions 
653 |a Hierarchies 
653 |a Words 
653 |a Information 
653 |a Eye tracking 
653 |a Environmental 
700 1 |a Frisson, Steven  |u Centre for Human Brain Health, School of Psychology, University of Birmingham, Birmingham, UK (ROR: https://ror.org/03angcq70) (GRID: grid.6572.6) (ISNI: 0000 0004 1936 7486) 
700 1 |a Pan, Yali  |u Centre for Human Brain Health, School of Psychology, University of Birmingham, Birmingham, UK (ROR: https://ror.org/03angcq70) (GRID: grid.6572.6) (ISNI: 0000 0004 1936 7486) 
700 1 |a Jensen, Ole  |u Centre for Human Brain Health, School of Psychology, University of Birmingham, Birmingham, UK (ROR: https://ror.org/03angcq70) (GRID: grid.6572.6) (ISNI: 0000 0004 1936 7486); Department of Experimental Psychology, University of Oxford, Oxford, UK (ROR: https://ror.org/052gg0110) (GRID: grid.4991.5) (ISNI: 0000 0004 1936 8948); Oxford Centre for Human Brain Activity, Oxford Centre for Integrative Neuroimaging, Department of Psychiatry, University of Oxford, Oxford, UK (ROR: https://ror.org/052gg0110) (GRID: grid.4991.5) (ISNI: 0000 0004 1936 8948) 
773 0 |t Nature Communications  |g vol. 16, no. 1 (2025), p. 8893-8905 
786 0 |d ProQuest  |t Health & Medical Collection 
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