Korsmeyer–Peppas Model for Diacetylaminoazotoluene (Dimazon) Release from PVA Foils: A Spectral Study

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Publicat a:Symmetry vol. 17, no. 10 (2025), p. 1739-1753
Autor principal: Gasner, Paul
Altres autors: Babusca Daniela, Vleoanga Andrei, Dorohoi, Dana Ortansa
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MDPI AG
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024 7 |a 10.3390/sym17101739  |2 doi 
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100 1 |a Gasner, Paul  |u Faculty of Physics, Alexandru Iona Cuza University, 11 Carol I Blvd., 700506 Iași, Romania; gasner@uaic.ro 
245 1 |a Korsmeyer–Peppas Model for Diacetylaminoazotoluene (Dimazon) Release from PVA Foils: A Spectral Study 
260 |b MDPI AG  |c 2025 
513 |a Journal Article 
520 3 |a Dimazon is known to stimulate the proliferation of epithelial cells. The dimazon released from locally attached polymer foils could be efficient for the treatment of skin damage. So, knowledge on the characteristics of the dimazon released from polymer matrices is important in establishing the continuous and predictable delivery of drug to a target. The spectrum of dimazon released from PVA foils is analysed based on the empirical Korsmeyer–Peppas model. The influence of the drug’s concentration and the film’s anisotropy, induced by stretching, on the delivery mechanism is highlighted. The results of this study could help clinical researchers establish a protocol for using dimazon from PVA foils in skin therapy. 
653 |a Polymers 
653 |a Toxicity 
653 |a Diuretics 
653 |a Experiments 
653 |a Epithelium 
653 |a Ulcers 
653 |a Calibration 
653 |a Solvents 
653 |a Edema 
653 |a Anisotropy 
653 |a Medical equipment 
653 |a Molecular weight 
653 |a Foils 
653 |a Drug dosages 
653 |a Ethanol 
700 1 |a Babusca Daniela  |u Department of Physics, Al. Vlahuta School, 10 Buridava Street, 700432 Iași, Romania; daniela.babusca@vlahuta.ro 
700 1 |a Vleoanga Andrei  |u Faculty of General Medicine, Gr. T. Popa University of Medicine and Pharmacy, 16 Universității Street, 700115 Iași, Romania; mg-rom-32917@students.umfiasi.ro 
700 1 |a Dorohoi, Dana Ortansa  |u Faculty of Physics, Alexandru Iona Cuza University, 11 Carol I Blvd., 700506 Iași, Romania; gasner@uaic.ro 
773 0 |t Symmetry  |g vol. 17, no. 10 (2025), p. 1739-1753 
786 0 |d ProQuest  |t Engineering Database 
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