Synchronous Occurrence of Gastric Signet Ring Cell Carcinoma and Pulmonary Fibrosarcoma in 23‐Year‐Old Male Youth

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Publicado en:Clinical Case Reports vol. 13, no. 11 (Nov 1, 2025)
Autor principal: Zhu, Meng
Otros Autores: Ma, Jingwei, Zhang, Ning, Li, Tao
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John Wiley & Sons, Inc.
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Acceso en línea:Citation/Abstract
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022 |a 2050-0904 
024 7 |a 10.1002/ccr3.71037  |2 doi 
035 |a 3267175968 
045 0 |b d20251101 
084 |a 239633  |2 nlm 
100 1 |a Zhu, Meng  |u College of Basic Medicine, Ningxia Medical University, Yinchuan, Ningxia, China 
245 1 |a Synchronous Occurrence of Gastric Signet Ring Cell Carcinoma and Pulmonary Fibrosarcoma in 23‐Year‐Old Male Youth 
260 |b John Wiley & Sons, Inc.  |c Nov 1, 2025 
513 |a Journal Article Case Study 
520 3 |a ABSTRACT The synchronous occurrence of epithelial‐derived gastric signet ring cell carcinoma and mesenchymal‐derived pulmonary fibrosarcoma in a single patient is extremely rare in clinical practice. Here, we report the case of a 23‐year‐old man who presented with hematemesis and melena for 6 days. Gastroscopy revealed two irregular small ulcers in the upper‐middle segment of the gastric body. CT imaging demonstrated uneven thickening of the gastric wall along the greater curvature, with local ulcer formation, as well as a small nodule in the left lower lobe of the lung. The patient underwent thoracotomy, and postoperative pathology confirmed signet ring cell carcinoma in the stomach and fibrosarcoma in the lung. The coexisting tumor was diagnosed in one patient although it is unknown whether it is an accidental event or is caused by some underlying mechanism that makes him develop different malignancy in different organs simultaneously. This report serves to alert clinicians to this rare condition. 
653 |a Medical diagnosis 
653 |a Spleen 
653 |a Metastasis 
653 |a Lung cancer 
653 |a Fibrosarcoma 
653 |a Liver 
653 |a Ulcers 
653 |a Lymphatic system 
653 |a Ostomy 
653 |a Abdomen 
653 |a Kidneys 
653 |a Tumors 
653 |a Gastric cancer 
653 |a Sarcoma 
653 |a Stomach 
653 |a Morphology 
700 1 |a Ma, Jingwei  |u The Second Department of Surgical Oncology, General Hospital of Ningxia Medical University, Yinchuan, Ningxia, China 
700 1 |a Zhang, Ning  |u Department of Pathology, General Hospital of Ningxia Medical University, Yinchuan, Ningxia, China 
700 1 |a Li, Tao  |u The Second Department of Surgical Oncology, General Hospital of Ningxia Medical University, Yinchuan, Ningxia, China 
773 0 |t Clinical Case Reports  |g vol. 13, no. 11 (Nov 1, 2025) 
786 0 |d ProQuest  |t Health & Medical Collection 
856 4 1 |3 Citation/Abstract  |u https://www.proquest.com/docview/3267175968/abstract/embedded/7BTGNMKEMPT1V9Z2?source=fedsrch 
856 4 0 |3 Full Text  |u https://www.proquest.com/docview/3267175968/fulltext/embedded/7BTGNMKEMPT1V9Z2?source=fedsrch 
856 4 0 |3 Full Text - PDF  |u https://www.proquest.com/docview/3267175968/fulltextPDF/embedded/7BTGNMKEMPT1V9Z2?source=fedsrch