Efficacy and safety of acupuncture for postoperative gastroparesis syndrome: a systematic review and meta-analysis

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I publikationen:Frontiers in Medicine vol. 11 (Jan 2025), p. 1494693-1494706
Huvudupphov: Xv, Yichuan
Övriga upphov: Feng, Yiyi, Jiang, Lin
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Frontiers Media SA
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022 |a 2296-858X 
024 7 |a 10.3389/fmed.2024.1494693  |2 doi 
035 |a 3270815795 
045 2 |b d20250101  |b d20250131 
100 1 |a Xv, Yichuan  |u Department of Gastroenterology, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China 
245 1 |a Efficacy and safety of acupuncture for postoperative gastroparesis syndrome: a systematic review and meta-analysis 
260 |b Frontiers Media SA  |c Jan 2025 
513 |a Journal Article 
520 3 |a BackgroundPostoperative gastroparesis syndrome (PGS) is a common postoperative complication characterized by epigastralgia, nausea, and vomiting. Acupuncture is widely used to aid recovery, but its efficacy and safety have not been systematically evaluated.MethodWe retrieved randomized controlled trials (RCTs) using acupuncture as the primary intervention from six databases. After study selection and data extraction, a meta-analysis was performed using Review Manager 5.4.1. Study quality was assessed with the Cochrane risk of bias tool, and publication bias was quantitatively evaluated using Egger’s test and was corrected using the trimming and filling method.ResultsA total of 12 RCTs involving 709 participants (363 in the acupuncture group and 346 in the control group) were included. The meta-analysis showed a significantly higher overall response rate in the acupuncture group than the control group [RD = 0.16, 95% CI (0.11, 0.21), p < 0.001]. Acupuncture also reduced gastric tube indwelling time [MD = −2.36, 95% CI (−3.14, −1.59), p < 0.001], decreased gastric juice drainage [MD = −166.88, 95% CI (−176.57, −156.18), p < 0.001], and improved serum motilin levels [MD = 41.65, 95% CI (30.14, 53.15), p < 0.001]. Four studies reported no adverse events in either group, but the majority of studies did not provide safety data.ConclusionAcupuncture may alleviate clinical symptoms and shorten hospitalization, potentially by enhancing gastrointestinal motility. However, the lack of safety data in the majority of studies raises concerns about the reliability of these findings and the transferability of the results. Future trials should focus on rigorous randomization, blinding, and comprehensive safety reporting to improve the quality of evidence in this field.Systematic review registrationID: INPLASY202320035 URL:https://inplasy.com/inplasy-2023-2-0035/ 
653 |a Clinical trials 
653 |a Vomiting 
653 |a Databases 
653 |a Acupuncture 
653 |a Nausea 
653 |a Abdomen 
653 |a Clinical medicine 
653 |a Systematic review 
653 |a Meta-analysis 
653 |a Asymmetry 
653 |a Bias 
653 |a Statistical analysis 
700 1 |a Feng, Yiyi  |u Department of Traditional Chinese Medicine, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, China 
700 1 |a Jiang, Lin  |u Department of Gastroenterology, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China 
773 0 |t Frontiers in Medicine  |g vol. 11 (Jan 2025), p. 1494693-1494706 
786 0 |d ProQuest  |t Health & Medical Collection 
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