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Field Notes on Moving Focused Research Organizations Forward

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Udgivet i:Issues in Science and Technology vol. 42, no. 1 (Fall 2025), p. 43-49
Hovedforfatter: Anonymous
Udgivet:
Issues in Science and Technology
Fag:
Cell culture
Function words
Genomes
Costs
Innovations
Cost reduction
Particle accelerators
Cost analysis
Gene sequencing
Startups
Deoxyribonucleic acid > DNA
Human Genome Project
Precision medicine
Proteomics
Nonprofit organizations
Clinical assessment
Atlases
Software
DNA sequencing
Scientists
Water sampling
Water analysis
Mathematics
Medicine
Genomics
Inventions
Infrastructure
Research centers
Economic
Intellectual Property
Innovation
Laboratory Experiments
Influence of Technology
Performance Contracts
Educational Technology
Trust (Psychology)
Research Tools
Scientific Enterprise
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Resumen:Over the last two decades, the cost of sequencing a million DNA base pairs fell from over $5,000 to less than a penny. That cost reduction enabled research across precision medicine, high-throughput small-molecule screening, species identification from air and water samples, atlases of gene activity and protein content for diverse cell types, virtual cell models, and many other applications, including many totally unanticipated by earlier DNA sequencing technologists. Consider what scientists wouldn't be doing as well or at all without that fundamental capacity. Low-cost sequencing came about via a fortuitous mixture of the government-funded Human Genome Project, academic discovery, and industry innovation. However, megaprojects like the Human Genome Project or the particle accelerators at CERN, as important and empowering as they have been, are rare one-offs. Many smaller-scale, critical gaps in capability remain, but the scientific enterprise is not set up to systematically identify, let alone bridge, these gaps.
ISSN:0748-5492
1938-1557
Fuente:Science Database