Effect of Moderate-to-High-Intensity Interval Aerobic Exercise on Clinical Symptoms During the Menstrual Cycle: A Pilot Randomized Controlled Trial

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Publicado en:Healthcare vol. 13, no. 23 (2025), p. 3113-3126
Autor principal: Pio-Soria Alejandra
Otros Autores: Zahran Doaa, Roldán-Ruiz, Alberto
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MDPI AG
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Acceso en línea:Citation/Abstract
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022 |a 2227-9032 
024 7 |a 10.3390/healthcare13233113  |2 doi 
035 |a 3280949049 
045 2 |b d20251201  |b d20251214 
084 |a 231469  |2 nlm 
100 1 |a Pio-Soria Alejandra  |u Departamento de Fisioterapia, Facultad de Ciencias de la Salud, Universidad Francisco de Vitoria, Ctra. Pozuelo-Majadahonda Km 1,800, Pozuelo de Alarcón, 28223 Madrid, Spain; alex.pio.soria@gmail.com 
245 1 |a Effect of Moderate-to-High-Intensity Interval Aerobic Exercise on Clinical Symptoms During the Menstrual Cycle: A Pilot Randomized Controlled Trial 
260 |b MDPI AG  |c 2025 
513 |a Journal Article 
520 3 |a Introduction: Primary dysmenorrhea is one of the most prevalent gynecological disorders. It has been shown to negatively impact quality of life and overall wellbeing, as recent studies have associated stress and physical inactivity with both the onset and severity of menstrual pain. Objective: To analyze the effectiveness of a moderate-to-high-intensity interval aerobic exercise on menstrual pain intensity, menstrual-related quality of life, general health-related quality of life, sleep quality, stress and anxiety, and drug intake in young women with primary dysmenorrhea. Methodology: A total of 20 women were randomly allocated to either the exercise (N = 10) or control group (N = 10). Primary outcomes were menstrual pain intensity and menstrual-related quality of life. Secondary outcomes included general health-related quality of life, sleep quality, stress and anxiety, and drug intake. A supervised moderate-to-high-intensity interval aerobic exercise program on a stationary bicycle was carried out twice a week, for eight weeks, in young women with regular cycles and no diagnosed medical conditions. Patients were assessed at baseline, and at 1- and 2-month follow-ups. Results: At 8 weeks, 17 women completed the follow-up. Analyses showed statistically significant differences in favor of moderate-to-high-intensity interval aerobic exercise at 2-month follow-up for menstrual pain intensity, with a large size effect. Significant changes were also found in menstrual-related quality of life at both follow-ups in the exercise group, but they were not superior to the control group. No significant changes were observed for the rest of the variables in either group. Conclusions: The results from this pilot study suggest that the moderate-to-high-intensity interval aerobic exercise program is effective in reducing menstrual pain intensity at 2-month follow-ups. Future randomized controlled trials with larger samples are required to confirm the results. 
610 4 |a Apple Inc 
651 4 |a Madrid Spain 
651 4 |a Spain 
653 |a Physiology 
653 |a Exercise 
653 |a Womens health 
653 |a Anxiety 
653 |a Physical fitness 
653 |a Menarche 
653 |a Self report 
653 |a Intervention 
653 |a Cytokines 
653 |a Questionnaires 
653 |a Fitness equipment 
653 |a Birth control 
653 |a Aerobics 
653 |a Analgesics 
653 |a Quality of life 
653 |a Nausea 
653 |a Perceptions 
653 |a Medical history 
653 |a Menstruation 
653 |a Medical research 
653 |a Nonsteroidal anti-inflammatory drugs 
653 |a Pain 
653 |a Heart rate 
700 1 |a Zahran Doaa  |u Departamento de Fisioterapia, Facultad de Ciencias de la Salud, Universidad Francisco de Vitoria, Ctra. Pozuelo-Majadahonda Km 1,800, Pozuelo de Alarcón, 28223 Madrid, Spain; alex.pio.soria@gmail.com 
700 1 |a Roldán-Ruiz, Alberto  |u Departamento de Fisioterapia, Facultad de Ciencias de la Salud, Universidad Francisco de Vitoria, Ctra. Pozuelo-Majadahonda Km 1,800, Pozuelo de Alarcón, 28223 Madrid, Spain; alex.pio.soria@gmail.com 
773 0 |t Healthcare  |g vol. 13, no. 23 (2025), p. 3113-3126 
786 0 |d ProQuest  |t Nursing & Allied Health Database 
856 4 1 |3 Citation/Abstract  |u https://www.proquest.com/docview/3280949049/abstract/embedded/KOLE7RPJVUKQAXRX?source=fedsrch 
856 4 0 |3 Full Text + Graphics  |u https://www.proquest.com/docview/3280949049/fulltextwithgraphics/embedded/KOLE7RPJVUKQAXRX?source=fedsrch 
856 4 0 |3 Full Text - PDF  |u https://www.proquest.com/docview/3280949049/fulltextPDF/embedded/KOLE7RPJVUKQAXRX?source=fedsrch