Proportional Hazards Modelling for Current Lifetime Data
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| Publicado en: | ProQuest Dissertations and Theses (2025) |
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ProQuest Dissertations & Theses
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| Acceso en línea: | Citation/Abstract Full Text - PDF Full text outside of ProQuest |
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| Resumen: | Current lifetime data represent a unique subset of length-biased data where only the times from the initiating event to the cross-section date are observed without follow-up. We propose an efficient estimation procedure to fit the semi-parametric proportional hazards model using current lifetime data. This estimation procedure is based on the EM algorithm which has two versions based on the support points of the non-parametric baseline hazard function. We apply the method to simulated data and Parkinson’s disease current lifetime data drawn from the Canadian-Open Parkinson Network (C-OPN). We estimate the effects of clinical and epidemiological covariates using the proportional hazards model on the survival of subjects with Parkinson’s disease. |
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| ISBN: | 9798270207915 |
| Fuente: | ProQuest Dissertations & Theses Global |