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Synchronous neuroendocrine tumor and signet ring cell carcinoma in the stomach: a case report and review of literature

Gorde:
Argitaratua izan da:Frontiers in Medicine vol. 12 (May 2025), p. 1561231-1561237
Egile nagusia: Han, Jian
Beste egile batzuk: Wang, Ying, Hanlin Mu, Liu, Jingmei
Argitaratua:
Frontiers Media SA
Gaiak:
Medical diagnosis
Gastrointestinal surgery
Tomography
Metastasis
Lymphatic system
Biopsy
Hospitals
Lesions
Neuroendocrine tumors
Abdomen
Antigens
Case reports
Gastric cancer
Stomach
Chemotherapy
Endoscopy
Sarrera elektronikoa:Citation/Abstract
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Laburpena:Synchronous neoplasms of the stomach are uncommon. Here we presented an unusual case with coexistence of neuroendocrine tumor and signet ring cell carcinoma in the stomach. Gastroscopic examination of a 66-year-old male patient showed a submucosal tumor-like mass with an ulcer on the surface located in the anterior wall of the lower segment of gastric body, confirmed by subsequent biopsy as a signet ring cell carcinoma. Moreover, we also found a slightly yellowish 6-mm protrusion simulating a polyp located in the lesser curvature of the upper segment of gastric body, and biopsy revealed it was a neuroendocrine tumor. The patient underwent a total gastrectomy with a standard D2 lymph node dissection. Pathohistological results led to the final diagnosis of synchronous neoplasms in the stomach, including a signet ring cell carcinoma and a neuroendocrine tumor.
ISSN:2296-858X
DOI:10.3389/fmed.2025.1561231
Baliabidea:Health & Medical Collection