Emerging Risk of Flea-Borne Bartonella in Tropical Cities: Evidence from Stray Cats in the Klang Valley, Malaysia
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| الحاوية / القاعدة: | Insects vol. 16, no. 12 (2025), p. 1282-1300 |
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| المؤلف الرئيسي: | |
| مؤلفون آخرون: | , , , , , |
| منشور في: |
MDPI AG
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| الموضوعات: | |
| الوصول للمادة أونلاين: | Citation/Abstract Full Text + Graphics Full Text - PDF |
| الوسوم: |
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MARC
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| 022 | |a 2075-4450 | ||
| 024 | 7 | |a 10.3390/insects16121282 |2 doi | |
| 035 | |a 3286307508 | ||
| 045 | 2 | |b d20251201 |b d20251231 | |
| 084 | |a 231475 |2 nlm | ||
| 100 | 1 | |a Titti, Alison Justin |u Higher Institution Centre of Excellence (HICoE), Tropical Infectious Diseases Research & Education Centre (TIDREC), Universiti Malaya, Kuala Lumpur 50603, Malaysia | |
| 245 | 1 | |a Emerging Risk of Flea-Borne <i>Bartonella</i> in Tropical Cities: Evidence from Stray Cats in the Klang Valley, Malaysia | |
| 260 | |b MDPI AG |c 2025 | ||
| 513 | |a Journal Article | ||
| 520 | 3 | |a Urban stray cats are often associated with ectoparasites and zoonotic pathogens due to their unsanitary living conditions and lack of veterinary care. Fleas, especially Ctenocephalides spp., are competent vectors of Bartonella spp., a genus of emerging bacterial pathogens with both public health and veterinary relevance. This study investigated the presence of Bartonella DNA in ectoparasitic fleas infesting stray cats in various urban habitats within the Klang Valley, Malaysia. A total of 204 fleas were collected from 89 stray cats. Fleas were identified morphologically using established taxonomic keys under a light microscope and further validated through PCR amplification of the mitochondrial cytochrome c oxidase subunit I (cox1) gene. Detection of Bartonella spp. was conducted by targeting the citrate synthase (gltA) gene. All fleas were confirmed as Ctenocephalides felis, with an infestation prevalence of 39.33% among the cats sampled. Of 118 C. felis specimens tested, 86.44% were positive for Bartonella DNA, one of the highest worldwide and significantly surpassing previous Malaysian reports. Sequencing of 12 positive samples showed identities with B. claridgeiae (58.3%), B. henselae (25.0%), an uncultured Bartonella species (8.3%) and a Bartonella isolate from a dog in Chile (8.3%). These results highlight the significant presence of Bartonella, causative agent of cat-scratch disease in stray cats, emphasizing their potential role as urban reservoirs and vectors. The findings underscore the need for ectoparasite surveillance and zoonotic pathogen control as integral components of stray animal management in Malaysia’s urban settings. | |
| 651 | 4 | |a Malaysia | |
| 653 | |a Infections | ||
| 653 | |a Public health | ||
| 653 | |a Urban environments | ||
| 653 | |a Animals | ||
| 653 | |a Ectoparasites | ||
| 653 | |a Disease control | ||
| 653 | |a Cities | ||
| 653 | |a Zoonoses | ||
| 653 | |a Urban areas | ||
| 653 | |a Cytochrome-c oxidase | ||
| 653 | |a Bacteria | ||
| 653 | |a Ethanol | ||
| 653 | |a Pathogens | ||
| 653 | |a Citrate synthase | ||
| 653 | |a Cats | ||
| 653 | |a Cat scratch disease | ||
| 653 | |a Deoxyribonucleic acid--DNA | ||
| 653 | |a Living conditions | ||
| 653 | |a Dengue fever | ||
| 653 | |a Vectors | ||
| 653 | |a Morphology | ||
| 653 | |a Health risks | ||
| 653 | |a Social | ||
| 653 | |a Ctenocephalides felis | ||
| 653 | |a Bartonella | ||
| 653 | |a Siphonaptera | ||
| 700 | 1 | |a AbdulHalim, Auni Atikah |u Higher Institution Centre of Excellence (HICoE), Tropical Infectious Diseases Research &amp; Education Centre (TIDREC), Universiti Malaya, Kuala Lumpur 50603, Malaysia | |
| 700 | 1 | |a Abdullah Halim Muhammad Rasul |u Department of Ecology and Biodiversity, Institute of Biological Sciences, Faculty of Science, Universiti Malaya, Kuala Lumpur 50603, Malaysia | |
| 700 | 1 | |a Yahaya Hasmawati |u Higher Institution Centre of Excellence (HICoE), Tropical Infectious Diseases Research &amp; Education Centre (TIDREC), Universiti Malaya, Kuala Lumpur 50603, Malaysia | |
| 700 | 1 | |a Aziz, Muhamad Afiq |u Department of Microbiology, Institute of Biological Sciences, Faculty of Science, Universiti Malaya, Kuala Lumpur 50603, Malaysia | |
| 700 | 1 | |a AbuBakar Sazaly |u Higher Institution Centre of Excellence (HICoE), Tropical Infectious Diseases Research &amp; Education Centre (TIDREC), Universiti Malaya, Kuala Lumpur 50603, Malaysia | |
| 700 | 1 | |a Ya’cob Zubaidah |u Higher Institution Centre of Excellence (HICoE), Tropical Infectious Diseases Research &amp; Education Centre (TIDREC), Universiti Malaya, Kuala Lumpur 50603, Malaysia | |
| 773 | 0 | |t Insects |g vol. 16, no. 12 (2025), p. 1282-1300 | |
| 786 | 0 | |d ProQuest |t Agriculture Science Database | |
| 856 | 4 | 1 | |3 Citation/Abstract |u https://www.proquest.com/docview/3286307508/abstract/embedded/7BTGNMKEMPT1V9Z2?source=fedsrch |
| 856 | 4 | 0 | |3 Full Text + Graphics |u https://www.proquest.com/docview/3286307508/fulltextwithgraphics/embedded/7BTGNMKEMPT1V9Z2?source=fedsrch |
| 856 | 4 | 0 | |3 Full Text - PDF |u https://www.proquest.com/docview/3286307508/fulltextPDF/embedded/7BTGNMKEMPT1V9Z2?source=fedsrch |