XIMED: A Dual-Loop Evaluation Framework Integrating Predictive Model and Human-Centered Approaches for Explainable AI in Medical Imaging
Guardado en:
| Publicado en: | Machine Learning and Knowledge Extraction vol. 7, no. 4 (2025), p. 168-205 |
|---|---|
| Autor principal: | |
| Otros Autores: | , |
| Publicado: |
MDPI AG
|
| Materias: | |
| Acceso en línea: | Citation/Abstract Full Text + Graphics Full Text - PDF |
| Etiquetas: |
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
MARC
| LEADER | 00000nab a2200000uu 4500 | ||
|---|---|---|---|
| 001 | 3286316714 | ||
| 003 | UK-CbPIL | ||
| 022 | |a 2504-4990 | ||
| 024 | 7 | |a 10.3390/make7040168 |2 doi | |
| 035 | |a 3286316714 | ||
| 045 | 2 | |b d20251001 |b d20251231 | |
| 100 | 1 | |a Karagoz Gizem | |
| 245 | 1 | |a XIMED: A Dual-Loop Evaluation Framework Integrating Predictive Model and Human-Centered Approaches for Explainable AI in Medical Imaging | |
| 260 | |b MDPI AG |c 2025 | ||
| 513 | |a Journal Article | ||
| 520 | 3 | |a In this study, a structured and methodological evaluation approach for eXplainable Artificial Intelligence (XAI) methods in medical image classification is proposed and implemented using LIME and SHAP explanations for chest X-ray interpretations. The evaluation framework integrates two critical perspectives: predictive model-centered and human-centered evaluations. Predictive model-centered evaluations examine the explanations’ ability to reflect changes in input and output data and the internal model structure. Human-centered evaluations, conducted with 97 medical experts, assess trust, confidence, and agreements with AI’s indicative and contra-indicative reasoning as well as their changes before and after provision of explainability. Key findings of our study include explanation of sensitivity of LIME and SHAP to model changes, their effectiveness in identifying critical features, and SHAP’s significant impact on diagnosis changes. Our results show that both LIME and SHAP negatively affected contra-indicative agreement. Case-based analysis revealed AI explanations reinforce trust and agreement when participant’s initial diagnoses are correct. In these cases, SHAP effectively facilitated correct diagnostic changes. This study establishes a benchmark for future research in XAI for medical image analysis, providing a robust foundation for evaluating and comparing different XAI methods. | |
| 653 | |a Image classification | ||
| 653 | |a Clinical decision making | ||
| 653 | |a Image analysis | ||
| 653 | |a Artificial intelligence | ||
| 653 | |a Localization | ||
| 653 | |a Medical imaging | ||
| 653 | |a Prediction models | ||
| 653 | |a Explainable artificial intelligence | ||
| 653 | |a Evaluation | ||
| 653 | |a Medical personnel | ||
| 700 | 1 | |a Tanir, Ozcelebi | |
| 700 | 1 | |a Meratnia Nirvana | |
| 773 | 0 | |t Machine Learning and Knowledge Extraction |g vol. 7, no. 4 (2025), p. 168-205 | |
| 786 | 0 | |d ProQuest |t Advanced Technologies & Aerospace Database | |
| 856 | 4 | 1 | |3 Citation/Abstract |u https://www.proquest.com/docview/3286316714/abstract/embedded/7BTGNMKEMPT1V9Z2?source=fedsrch |
| 856 | 4 | 0 | |3 Full Text + Graphics |u https://www.proquest.com/docview/3286316714/fulltextwithgraphics/embedded/7BTGNMKEMPT1V9Z2?source=fedsrch |
| 856 | 4 | 0 | |3 Full Text - PDF |u https://www.proquest.com/docview/3286316714/fulltextPDF/embedded/7BTGNMKEMPT1V9Z2?source=fedsrch |