Innovative Regenerative Treatment with Nanofat Injection for Hypertensive Ischemic Leg Ulcer: A Case Report

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Publicat a:Case Reports in Dermatology vol. 17, no. 1 (Jan-Dec 2025), p. 342
Autor principal: Terrasa, Mélodie
Altres autors: Majzoub, Marwa, Jeudy, Geraldine, Moris, Vivien
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S. Karger AG
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100 1 |a Terrasa, Mélodie 
245 1 |a Innovative Regenerative Treatment with Nanofat Injection for Hypertensive Ischemic Leg Ulcer: A Case Report 
260 |b S. Karger AG  |c Jan-Dec 2025 
513 |a Case Study 
520 3 |a Introduction Chronic wounds affect millions worldwide, leading to significant morbidity and reduced quality of life [1]. The patient reported severe pain with a VAS = 8/10 (Visual Analog Scale) and mobility restrictions, significantly impairing her quality of life. The procedure began with an infiltration of 100 cm3 of 0.9% NaCl diluted with a solution containing 1% lidocaine hydrochloride (10 mg/mL) and adrenaline (0.005 mg/mL) at the donor site (periumbilical region). The treatment not only resulted in the complete healing of a chronic wound persisting for over 5 years, despite previous skin graft failures, but also significantly reduced pain and improved the patient’s quality of life. In this case, the pain was severe, with a VAS of 8/10, associated with mobility restrictions and a significant impairment of her quality of life. 
653 |a Leg ulcers 
653 |a Liposuction 
653 |a Quality of life 
653 |a Plastic surgery 
653 |a Wound healing 
653 |a Adipocytes 
653 |a Hypertension 
653 |a Body fat 
653 |a Pain 
653 |a Females 
653 |a Ischemia 
653 |a Skin & tissue grafts 
653 |a Local anesthesia 
653 |a Patient satisfaction 
653 |a Narcotics 
653 |a Analgesics 
700 1 |a Majzoub, Marwa 
700 1 |a Jeudy, Geraldine 
700 1 |a Moris, Vivien 
773 0 |t Case Reports in Dermatology  |g vol. 17, no. 1 (Jan-Dec 2025), p. 342 
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