Contractile force measurements of cardiac myocytes using a micro-manipulation system

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Pubblicato in:Journal of Mechanical Science and Technology vol. 20, no. 5 (May 2006), p. 668
Autore principale: Park, Sukho
Altri autori: Ryu, Seokkyu, Ryu, Seokchang, Kim, Deokho, Kim, Byungkyu
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Springer Nature B.V.
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100 1 |a Park, Sukho 
245 1 |a Contractile force measurements of cardiac myocytes using a micro-manipulation system 
260 |b Springer Nature B.V.  |c May 2006 
513 |a Feature 
520 3 |a In order to develop a cell based robot, we present a micro-mechanical force measurement system for the biological muscle actuators, which utilize glucose as a power source. The proposed measurement system is composed of a micro-manipulator, a force transducer with a glass probe, a signal processor, an inverted microscope and video recording system. Using this measurement system, the contractile force and frequency of the cardiac myocytes were measured in real time and the magnitudes of the contractile force of each cardiac myocyte under different conditions were compared. From the quantitative experimental results, we could estimate that the force of cardiac myocytes is about 20-40 μN, and show that there are differences between the control cells and the micro-patterned cells.[PUBLICATION ABSTRACT] 
653 |a Heart 
653 |a Proteins 
700 1 |a Ryu, Seokkyu 
700 1 |a Ryu, Seokchang 
700 1 |a Kim, Deokho 
700 1 |a Kim, Byungkyu 
773 0 |t Journal of Mechanical Science and Technology  |g vol. 20, no. 5 (May 2006), p. 668 
786 0 |d ProQuest  |t Advanced Technologies & Aerospace Database 
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