Physiologically-based pharmacokinetic (PBPK) modeling and simulations : principles, methods, and applications in the pharmaceutical industry /
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| Main Author: | |
|---|---|
| Format: | Electronic eBook |
| Language: | English |
| Published: |
Hoboken, N.J. :
Wiley,
[2011]
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| Subjects: | |
| Online Access: | https://biblioteca.ues.edu.sv/acceso/elibro/?url=https%3A%2F%2Felibro.net%2Fereader%2Fbiblioues/180089 View in OPAC |
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| 020 | |a 9781118140383 |q (ebook) | ||
| 020 | |z 9780470484067 |q (print) | ||
| 035 | |a (OCoLC)723035162 | ||
| 040 | |a FINmELB |b eng |e rda |c FINmELB | ||
| 050 | 4 | |a RM301.5 |b .P48 2011 | |
| 082 | 0 | 4 | |a 615/.7 |2 23 |
| 100 | 1 | |a Peters, Sheila Annie. | |
| 245 | 1 | 0 | |a Physiologically-based pharmacokinetic (PBPK) modeling and simulations : |b principles, methods, and applications in the pharmaceutical industry / |c Sheila Annie Peters. |
| 264 | 1 | |a Hoboken, N.J. : |b Wiley, |c [2011] | |
| 264 | 4 | |c Ã2011 | |
| 300 | |a xvii, 430 p. : |b ill. | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
| 338 | |a online resource |b cr |2 rdacarrier | ||
| 347 | |a data file |2 rda | ||
| 504 | |a Includes bibliographical references and index. | ||
| 505 | 0 | |a Modelling in the pharmaceutical industry -- Physiologically-based modelling -- A review of pharmacokinetic principles -- Physiological model for absorption -- Physiological model for distribution -- Physiological models for drug metabolism and excretion -- Generic whole-body physiologically-based pharmacokinetic modelling -- Variability, uncertainty and sensitivity analysis -- Evaluation of drug-drug interaction risk with pbpk models -- PBPK of biotherapeutics -- Data integration and sensitivity analysis -- Hypothesis generation and pharmacokinetic predictions -- Integration of PBPK and pharmacodynamics -- PBPK modelling of populations -- PBPK models along the drug discovery and development value chain. | |
| 588 | |a Description based on metadata supplied by the publisher and other sources. | ||
| 590 | |a Electronic resource. Santa Fe, Argentina: elibro, 2025. Available via the World Wide Web. Access may be limited to libraries affiliated with elibro. | ||
| 650 | 0 | |a Pharmacokinetics |x Mathematical models. | |
| 650 | 0 | |a Drugs |x Design |x Mathematical models. | |
| 655 | 4 | |a Electronic books. | |
| 797 | 2 | |a elibro, Corp. | |
| 856 | 4 | 0 | |u https://biblioteca.ues.edu.sv/acceso/elibro/?url=https%3A%2F%2Felibro.net%2Fereader%2Fbiblioues/180089 |