(Unlearned) lessons from John Graunt and Kenneth Rothman: A "CLASSic" example
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| Publicado en: | Clinical Therapeutics vol. 25, no. 11 (Nov 2003), p. 2891 |
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| Publicado: |
Elsevier Limited
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| Acceso en línea: | Citation/Abstract Full Text Full Text - PDF |
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| 084 | |a 170329 |2 nlm | ||
| 100 | 1 | |a Arellano, Felix M. | |
| 110 | 2 | |a Class | |
| 245 | 1 | |a (Unlearned) lessons from John Graunt and Kenneth Rothman: A "CLASSic" example | |
| 260 | |b Elsevier Limited |c Nov 2003 | ||
| 513 | |a FLA Commentary Journal Article | ||
| 520 | 3 | |a This commentary reviews the work of John Graunt and Kenneth J. Rothman on statistical significance and the need for prespecification of study end points. The authors argue that it is dangerous to substitute oversimplifications based exclusively on whether a result has reached statistical significance for a rational process of causal inference. An example is given based on the Celecoxib Lonngterm Arthritis Safety Study. This commentary reviews the work of John Graunt and Kenneth J. Rothman on statistical significance and the need for prespecification of study end points. The authors argue that it is dangerous to substitute oversimplifications based exclusively on whether a result has reached statistical significance for a rational process of causal inference. An example is given based on the Celecoxib Long-term Arthritis Safety Study. | |
| 650 | 2 | 2 | |a Anti-Inflammatory Agents, Non-Steroidal |x adverse effects |
| 650 | 2 | 2 | |a Data Interpretation, Statistical |
| 650 | 2 | 2 | |a Endpoint Determination |
| 650 | 1 | 2 | |a Epidemiologic Methods |
| 650 | 2 | 2 | |a Epidemiologic Research Design |
| 650 | 2 | 2 | |a Humans |
| 650 | 2 | 2 | |a Peptic Ulcer |x chemically induced |
| 650 | 2 | 2 | |a Randomized Controlled Trials as Topic |
| 700 | 1 | |a Castellsague, Jordi | |
| 773 | 0 | |t Clinical Therapeutics |g vol. 25, no. 11 (Nov 2003), p. 2891 | |
| 786 | 0 | |d ProQuest |t Healthcare Administration Database | |
| 856 | 4 | 1 | |3 Citation/Abstract |u https://www.proquest.com/docview/1032773064/abstract/embedded/6A8EOT78XXH2IG52?source=fedsrch |
| 856 | 4 | 0 | |3 Full Text |u https://www.proquest.com/docview/1032773064/fulltext/embedded/6A8EOT78XXH2IG52?source=fedsrch |
| 856 | 4 | 0 | |3 Full Text - PDF |u https://www.proquest.com/docview/1032773064/fulltextPDF/embedded/6A8EOT78XXH2IG52?source=fedsrch |